Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,026 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT02437396Recruiting
Blood tests in stable adults with Gaucher disease
This study measures inflammation and “oxidative stress” (cell stress caused by imbalance in the body) using blood biomarkers in adults with Gaucher disease. It may help researchers understand what’s happening in the body and how treatment status relates to these blood signals.
Minneapolis, MinnesotaAges 18–75 - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT01316783Enrolling by invitation
Genetics study of obesity, diabetes, and heart risk
This study looks at genetic differences in adults from African diaspora groups to better understand risks for obesity, type 2 diabetes, and heart disease. You may help scientists learn why these conditions are more common in certain communities.
Bethesda, MarylandAges 18–120 - NCT01399385Recruiting
New heart imaging to detect heart disease
This study tests new imaging techniques, like MRI and CT scans, to better see heart and blood vessel problems. It may help doctors find heart disease earlier and guide treatment.
Bethesda, MarylandAges 18–100 - NCT01432847Recruiting
Collecting eye-related samples to study eye diseases
This study collects samples like blood and a small skin biopsy (and sometimes urine, hair, or saliva) to better understand causes of eye diseases. The goal is to study eye conditions and may help researchers build better tests or treatments.
Bethesda, MarylandAges 1 day–120 years - NCT01682668Recruiting
Deep brain stimulation study for Parkinson movement problems
This study looks at how deep brain stimulation (an implanted brain device) affects Parkinson’s symptoms, especially movement problems like freezing, slowness, or involuntary movements. It may help people whose symptoms are not fully controlled by standard Parkinson medicines.
Paris, PARISAges 18–70 - NCT00272883Recruiting
Study genes in congenital muscle weakness
This research study looks at genes and molecules to better understand congenital myopathies (birth-related muscle weakness). It may help explain the cause of symptoms and improve future diagnoses for you and your family.
Boston, MassachusettsAges Any age - NCT00628199Enrolling by invitation
Skin sample study to create future cell therapies
This study collects skin cells from people with certain long-term conditions (or specific genetic disorders). Researchers use the cells to try to build new treatments for human disease and disability in the future.
Stanford, CaliforniaAges 1–75 - NCT00001230Recruiting
Understanding How Your Body Responds to Filarial Infection
This study looks at how the body's immune system reacts to filarial infections—parasitic worms that affect millions worldwide. Researchers will observe your infection and response to treatment to better understand the disease and improve future care.
Bethesda, MarylandAges 3–100 - NCT00091871Recruiting
Understanding familial high eosinophil disease in families
This study follows families with a genetic condition that causes high levels of white blood cells called eosinophils. Researchers want to understand how the disease develops and changes over time to help predict who may get worse and how to treat it better.
Bethesda, MarylandAges 1–100 - NCT00009243Recruiting
Understanding How Strokes Develop: A Research Study
This study follows people who have had or are at risk for stroke to understand what causes strokes and how they develop over time. By participating, you help researchers learn more about stroke prevention and treatment.
Washington D.C., District of ColumbiaAges 18–120 - NCT00006150Recruiting
Understanding Hyper-IgE Syndrome: Natural History and Genetics
This study follows people with or suspected Hyper-IgE syndrome (a rare immune disorder causing repeated infections and skin problems) to understand how the condition develops, how best to manage it, and which genes are involved. Researchers also welcome healthy relatives of patients to help identify genetic patterns.
Bethesda, MarylandAges 1 month–120 years - NCT00092235Recruiting
Understanding chronic graft-versus-host disease outcomes
This study follows patients who have had a stem cell transplant and developed chronic graft-versus-host disease (a condition where transplanted cells attack the body). Researchers will track your symptoms and collect blood samples to understand what affects how well patients do over time.
Bethesda, MarylandAges 1–120 - NCT00557726Recruiting
Evaluation and care for inflammatory or infectious illnesses
This trial helps doctors evaluate possible infection or inflammation and decide on the best management plan. You may be able to receive specialized care at the NIH if the study team thinks your situation fits.
Bethesda, MarylandAges 3–100 - NCT00004847RecruitingPhase 1
Understanding and Diagnosing Pheochromocytoma and Paraganglioma
This study helps doctors better understand and diagnose pheochromocytoma and paraganglioma—rare tumors that release stress hormones and cause high blood pressure and other symptoms. Researchers will study your medical history, blood and urine tests, imaging scans, and genetic information to improve how these conditions are found and understood.
Bethesda, MarylandAges 3–120 - NCT00001215Enrolling by invitation
Understanding Genetic Lysosomal Storage Disorders
This study aims to understand genetic factors in lysosomal storage disorders—rare conditions where the body cannot break down certain substances. Researchers will collect information from patients with these disorders, their family members, and healthy volunteers to learn how these diseases develop and affect people over time.
Bethesda, MarylandAges 1 week–110 years - NCT00032513Recruiting
Genetic study of chronic active Epstein-Barr virus disease
This research study looks for genetic factors that may explain why some people develop severe, long-lasting Epstein-Barr virus (EBV) infection. Researchers will study blood and tissue samples from patients with this rare condition, their healthy relatives, and unrelated volunteers to understand the disease better.
Bethesda, MarylandAges 1–120 - NCT07706686RecruitingPhase 1
Safety and effects of a weakened dengue virus in volunteers
This study tests how the body reacts when volunteers are deliberately infected with a weakened version of the dengue virus. You will be closely monitored and this may help develop better vaccines for dengue.
Bethesda, MarylandAges 18–50 - NCT06615843Recruiting
Digital follow-up after emergency gynecology visit
This study tests a smartphone app to manage follow-up care after a visit to the emergency gynecology department, instead of the usual in-person visits. It aims to make follow-up easier and more convenient for women with certain pregnancy-related or gynecologic conditions.
ParisAges 18–60 - NCT06067451Recruiting
Smart goals for teens with prediabetes
This program helps teens with prediabetes set and reach healthy lifestyle goals. It focuses on weight management and diet changes to help prevent type 2 diabetes.
New York, New YorkAges 10–18 - NCT07883070Recruiting
Screening for anxiety and depression in blood cancer patients
This study looks at how common anxiety and depression are in people with blood cancers. It uses questionnaires to screen your mood, which may help your care team support you better.
Xiamen, FujianAges Any age - NCT07883499Recruiting
Heart imaging after bypass surgery
This study uses a new type of CT scan to check how well your heart is recovering three months after coronary artery bypass surgery. It aims to see if the scan can detect early problems that might need attention.
BeijingAges 18–100 - NCT07509034RecruitingPhase 1
Targeted immune cells for recurrent small cell lung cancer
This trial tests a special immune cell therapy (CAR T cells) that targets a protein called B7-H3 on your cancer cells. It is for people with small cell lung cancer or similar neuroendocrine cancers that have returned or not responded to standard treatments.
Bethesda, MarylandAges 18–120
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,026 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.