Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,022 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07215858RecruitingPhase 2
Testing a new flu vaccine against H1N1 flu
This study tests an experimental flu vaccine (BPL-1357) in healthy volunteers who will later be exposed to H1N1 flu virus in a controlled setting, to see if the vaccine can prevent or reduce illness.
Bethesda, MarylandAges 18–55 - NCT06647069RecruitingPhase 1
Testing a new drug for lupus and rheumatoid arthritis
This study tests an investigational drug called SAR448501/DR-0201 in people with active lupus or rheumatoid arthritis who have not responded well to standard treatments. The goal is to see if the drug is safe and helps control disease activity.
Melbourne, VictoriaAges 18–75 - NCT07027826Recruiting
String test for eosinophilic esophagitis in African patients
This study tests a new, less invasive way (the Esophageal String Test) to look for signs of eosinophilic esophagitis—an allergic condition that can make swallowing painful or difficult. It is for people of African descent who have trouble swallowing and are already having an endoscopy.
Bethesda, MarylandAges 18–65 - NCT07123519RecruitingPhase 1
YTS109 cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with certain severe autoimmune diseases that have not responded to standard treatments, such as lupus, Sjögren's syndrome, systemic sclerosis, inflammatory myopathy, vasculitis, and antiphospholipid syndrome. The goal is to see if it can safely reduce disease activity.
TianjinAges 18–65 - NCT06479837Recruiting
Study using tonsil tissue to understand infections
This study uses tonsil tissue that is removed during a routine tonsillectomy to grow tiny 'organoids' in the lab. Researchers will study how germs interact with human cells, which could lead to better treatments for infections.
Bethesda, MarylandAges 2–120 - NCT07712939RecruitingPhase 1
Study of CND319 for rheumatic diseases
This study tests a new drug called CND319 in healthy volunteers and people with rheumatoid arthritis or Sjögren's disease. The goal is to see if it is safe and how the body responds to it.
Melbourne, VictoriaAges 18–65 - NCT07509034RecruitingPhase 1
Targeted immune cells for recurrent small cell lung cancer
This trial tests a special immune cell therapy (CAR T cells) that targets a protein called B7-H3 on your cancer cells. It is for people with small cell lung cancer or similar neuroendocrine cancers that have returned or not responded to standard treatments.
Bethesda, MarylandAges 18–120 - NCT07706686RecruitingPhase 1
Safety and effects of a weakened dengue virus in volunteers
This study tests how the body reacts when volunteers are deliberately infected with a weakened version of the dengue virus. You will be closely monitored and this may help develop better vaccines for dengue.
Bethesda, MarylandAges 18–50 - NCT06615843Recruiting
Digital follow-up after emergency gynecology visit
This study tests a smartphone app to manage follow-up care after a visit to the emergency gynecology department, instead of the usual in-person visits. It aims to make follow-up easier and more convenient for women with certain pregnancy-related or gynecologic conditions.
ParisAges 18–60 - NCT06067451Recruiting
Smart goals for teens with prediabetes
This program helps teens with prediabetes set and reach healthy lifestyle goals. It focuses on weight management and diet changes to help prevent type 2 diabetes.
New York, New YorkAges 10–18 - NCT07883070Recruiting
Screening for anxiety and depression in blood cancer patients
This study looks at how common anxiety and depression are in people with blood cancers. It uses questionnaires to screen your mood, which may help your care team support you better.
Xiamen, FujianAges Any age - NCT07883499Recruiting
Heart imaging after bypass surgery
This study uses a new type of CT scan to check how well your heart is recovering three months after coronary artery bypass surgery. It aims to see if the scan can detect early problems that might need attention.
BeijingAges 18–100 - NCT07703436RecruitingPhase 2
Safusidenib for people with IDH-mutant glioma whose tumor progressed on vorasidenib
This trial tests a new targeted therapy called safusidenib for people whose brain tumor (glioma) has an IDH1 mutation and who have already taken vorasidenib but the tumor kept growing. The study aims to see if safusidenib can help when vorasidenib stops working.
Los Angeles, CaliforniaAges 18 years+ - NCT06607458RecruitingPhase 2
Liver-focused chemo for metastatic colorectal cancer
This trial tests giving high-dose melphalan directly into the liver's blood supply, followed by standard cancer therapy, for people whose colorectal cancer has spread mainly to the liver. The goal is to see if this approach is safer and works better than standard treatment alone.
Duarte, CaliforniaAges 18 years+ - NCT06356220Recruiting
Gluten-free nutrition for kids with celiac disease
This study helps children with newly diagnosed celiac disease eat a healthier gluten-free diet by reducing processed foods. It aims to improve nutrition and overall health.
Boston, MassachusettsAges 2–18 - NCT07411664Enrolling by invitation
Balance and walking study for stroke, Parkinson's, or multiple sclerosis
This study uses special motion-tracking tools to measure balance and trunk control in people with first-time stroke, Parkinson’s, or multiple sclerosis. It aims to understand how these conditions affect stability, which could help tailor rehabilitation.
Kaposvár, Somogy CountyAges 18–80 - NCT07288216RecruitingPhase 2
Switching to KPL-387 alone for well-controlled pericarditis
This study tests whether a new drug, KPL-387, can keep your pericarditis under control as your only treatment, after you have been stable on other medicines. It is for people whose pericarditis is well controlled now but who have had flares in the past.
Phoenix, ArizonaAges 18–80 - NCT07440186Recruiting
Collagen implant for severe corneal melting
This study tests whether a collagen implant can help heal a severely damaged cornea (the clear front part of the eye) when standard treatments haven't worked. It may offer a new option to stop the cornea from breaking down further.
Madrid, MadridAges 18 years+ - NCT06498349Recruiting
DBS for Parkinson's impulse control problems
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
CologneAges 18–70 - NCT07297914RecruitingPhase 2/Phase 3
Improving stem cell transplant for childhood leukemia
This trial tests different ways to manage stem cell transplants in children and young adults with acute lymphoblastic leukemia (ALL). It aims to find the best approach to improve outcomes and reduce complications.
ViennaAges 3 months–25 years - NCT03970096RecruitingPhase 2
Reduce graft-versus-host disease after stem cell transplant
This Phase 2 study tests ways to lower the risk of graft-versus-host disease (GVHD), a serious complication after an allogeneic stem cell transplant from a matched donor. It is for people with acute leukemia or MDS who are going to receive intensive conditioning therapy, aiming to improve safety while keeping the transplant effective.
Tampa, FloridaAges 1–60 - NCT07549698RecruitingPhase 1/Phase 2
CRISPR Gene Therapy for Immune Blood Disorders
This trial tests CTX112, a new CRISPR gene therapy that modifies your immune cells to treat severe immune thrombocytopenic purpura (ITP) or warm autoimmune hemolytic anemia (WAIHA) that hasn't responded to standard treatments. The goal is to see if it's safe and can help your body stop attacking its own blood cells.
Boston, MassachusettsAges 18 years+ - NCT07350057RecruitingPhase 1
Preventing graft-versus-host disease in children after stem cell transplant
This study tests a combination of three drugs (cyclophosphamide, sirolimus, and VIC-1911) to prevent graft-versus-host disease (GVHD), a common complication after a stem cell transplant. It is for children aged 8-18 with certain blood diseases who are undergoing a haploidentical stem cell transplant.
Shanghai, Shanghai MunicipalityAges 8–18 - NCT07304154RecruitingPhase 1
Experimental cell therapy for autoimmune nerve and muscle diseases
This study tests a new treatment called KITE-363 for people with certain autoimmune diseases that have not improved with standard treatments. It aims to see if the therapy is safe and helpful for conditions like multiple sclerosis, myasthenia gravis, and chronic inflammatory demyelinating polyneuropathy.
Newport Beach, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,022 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.