Clinical trials
Musculoskeletal Pain Disorder clinical trials
Below are recruiting musculoskeletal pain disorder clinical trials, each written for real people, not researchers. We’re tracking 61 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT07008105Recruiting
One session therapy for chronic pain
This study tests whether a single 90-minute online session can help people with chronic pain feel better. If you live with ongoing pain and want to try a brief psychological approach without medication, you may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT07764354Recruiting
Patient education for sticking with home exercises
This study tests whether extra education helps people with chronic musculoskeletal conditions—like long-term back pain, knee arthritis, or partial rotator cuff tears—stick with their home exercise routines to feel better. If you have one of these conditions and are willing to follow a home exercise plan, this could help you manage pain.
Dammam, Eastern ProvinceAges Any age - NCT05555576Recruiting
Vitamin C to reduce opioid use after an ER visit
This trial tests whether taking vitamin C after an emergency room visit for a new, short-term muscle or joint pain can lower how many opioid pain pills you use. It may help by reducing opioid consumption while you recover.
Montreal, QuebecAges 18 years+ - NCT06004804Recruiting
Video group therapy for chronic pain in older Veterans
This study tests whether group therapy sessions held over video can help older Veterans manage chronic muscle or joint pain. It focuses on teaching practical skills to reduce pain and improve quality of life.
West Los Angeles, CaliforniaAges 60–95 - NCT07494734Enrolling by invitation
Manual therapy for neck pain, disability, and quality of life
This study tests whether manual therapy (hands-on techniques) can reduce neck pain, improve daily function, and enhance quality of life for people with long-term neck pain.
Kocaeli, GebzeAges 18–65 - NCT07637552Enrolling by invitation
Deep vs. Shallow Needle Treatment for Neck Pain
This study compares two ways of using dry needling (a technique where thin needles are inserted into tight muscles) to treat neck pain caused by muscle knots. Researchers will use ultrasound and electrical testing to see which approach works better and is safer.
Dammam, Eastern ProvinceAges 18–65 - NCT06530459RecruitingPhase 2/Phase 3
The MUSE Study for Menopausal Joint Pain
This study tests whether a treatment can help women with joint pain and stiffness that started or worsened during menopause. It focuses on women who are within 5 years of menopause and have pain in multiple joints.
SingaporeAges 30–59 - NCT06398847Recruiting
Virtual reality self-hypnosis for HIV-related pain
This study tests if using a virtual reality (VR) headset for self-hypnosis can help people with HIV manage chronic pain. You would practice at home with a smartphone app, and researchers will track your pain levels over time.
New York, New YorkAges 18 years+ - NCT04860141RecruitingPhase 4
Gabapentin before wisdom tooth removal to reduce pain
This trial tests whether taking gabapentin before extracting a wisdom tooth helps with pain and comfort after the procedure. It may help people who need a third-molar removal, if they meet the safety and health requirements.
Loma Linda, CaliforniaAges 18–59 - NCT07137754Recruiting
Physiotherapy for minor injuries in the emergency department
This study tests whether a physiotherapy-led care model in the emergency department can help people with minor muscle or bone injuries recover better and at a lower cost. If you join, you'll see a physiotherapist instead of a doctor for your arm or leg injury.
Aarhus NAges 18 years+ - NCT07179016Recruiting
Acupressure for chronic pain in rural areas
This trial tests if a self-managed acupressure program can help people living in rural areas manage long-term muscle or joint pain, like neck, back, or knee pain. You would learn to press small seeds on your ear to ease pain.
Columbia, South CarolinaAges 18–85 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT07732062Recruiting
Emotion-focused therapy for chronic pain patients using medical cannabis
This study tests a new type of talking therapy (vEAET-H) to see if it helps people with chronic pain who are already using medical cannabis. The goal is to find out if adding this therapy can improve pain and well-being.
Tel AvivAges 18 years+ - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT07554664Recruiting
Desk Work, Stress, and Muscle Pain With or Without Migraine
This study looks at how office work, job stress, and muscle tension relate to migraines and neck/shoulder pain in desk workers. Researchers want to understand if certain body changes (called central sensitization) connect these issues, which could lead to better ways to help office workers feel better.
Gaziantep, MerkezAges 18–65 - NCT07245303Recruiting
How Light Affects Pain in Chronic Pain
This study looks at how different kinds of light might change pain levels in people with chronic widespread pain, like fibromyalgia. By using brain scans (MRI), researchers hope to find new ways to manage pain without medication.
Chapel Hill, North CarolinaAges 18 years+ - NCT07442383Recruiting
Exercise and ergonomics program for teachers with pain
This study tests whether an exercise and ergonomics training program can help teachers with long-term muscle or joint pain feel better. You would learn simple exercises and better ways to move at work to reduce discomfort.
Bitlis, TatvanAges 30–60 - NCT07347054Recruiting
Trigger point injection for shoulder arthritis pain
This study tests whether injecting a medication into painful knots in the shoulder muscle can reduce pain from shoulder arthritis. It may be a good option if you have had shoulder pain for at least 3 months and other treatments haven't worked well enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99
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Common questions
- Are there clinical trials for musculoskeletal pain disorder?
- Yes. Clin2 currently lists 61 recruiting musculoskeletal pain disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal pain disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal pain disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.