Clinical trials
Musculoskeletal clinical trials
Below are recruiting musculoskeletal clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06549660Recruiting
Light therapy for chronic low back pain relief
This study tests if a special light treatment (photobiomodulation) can temporarily ease chronic low back pain that comes and goes. It's for people who have had this pain for at least 3 months and speak Portuguese.
São PauloAges 18–65 - NCT06565481Recruiting
Testing movement and function in people with hemophilia
This study looks at how well certain tests measure movement and function in people with hemophilia. It may help improve how doctors track your condition.
ZurichAges 18 years+ - NCT01422694Recruiting
Understanding spondyloarthritis over time
This study follows people with spondyloarthritis (an inflammatory arthritis that often affects the spine and joints) and their family members over time to better understand how the disease develops and progresses. It also includes a research stool sample test to learn about gut bacteria.
Bethesda, MarylandAges 2–99 - NCT06621914Recruiting
Blood flow restriction training for military with leg injuries
This trial tests a low-weight exercise program using a special cuff on the leg (blood flow restriction) to see if it helps military personnel recover from leg injuries faster. It could be an option if pain is stopping you from doing normal rehab.
Loughborough, LeicestershireAges 18–55 - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06635668Recruiting
ACL injury risk screening study for athletes
This study screens healthy athletes aged 10 to 65 to understand what normal ACL injury risk looks like. It helps set a baseline so doctors can better identify those at higher risk.
Fargo, North DakotaAges 10–65 - NCT06642948Recruiting
AI system for exercise rehab in breast cancer survivors
This study tests a new AI-based skeleton recognition system to guide rehabilitation exercises for breast cancer survivors. It may help reduce pain and improve mobility for those taking aromatase inhibitors.
ShanghaiAges Any age - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT07685418Recruiting
Pressure therapy and home exercises for neck pain
This trial tests whether a hands-on technique called ischemic compression (applying gentle pressure to trigger points) plus home exercises helps relieve long-term neck pain that has no specific medical cause.
Istanbul, BakırköyAges 17–65 - NCT07683273Enrolling by invitation
Breathing exercises for neck and upper back pain
This study tests whether diaphragmatic breathing exercises can help reduce chronic, non-specific neck and upper back pain. If you have this type of pain that is not caused by an injury or disease, you may be able to join.
Trabzon, OrtahisarAges 18–60 - NCT06716489Recruiting
Exercise study for women with migraine
This study tests whether aerobic exercise can help reduce migraine symptoms and improve how your body senses and responds to pain. It is specifically for women aged 18–48 who have migraine headaches 3–8 days per month.
Ribeirão Preto, São PauloAges 18–48 - NCT06773169Recruiting
Testing an app for self-managing chronic conditions
This study tests a smartphone or computer app designed to help people with long-term health conditions like arthritis, heart disease, or stroke manage their own recovery. The goal is to see if using the app improves daily living and reduces disability.
Hamilton, OntarioAges 44–75 - NCT06797492Recruiting
Virtual Reality for Shoulder Problems
This trial tests whether virtual reality (a computer-made, 3D environment) can help people with shoulder problems recover better. You would use a VR headset for exercises, and the study will see if it improves your shoulder movement or pain.
Roma, ItalyAges 18–75 - NCT06809283Recruiting
Study of Intelect devices for muscle and joint pain
This study is observing how well Intelect devices work for people with muscle or joint problems in everyday medical care. It aims to confirm the devices are safe and effective.
SerrisAges 18 years+ - NCT06813495Recruiting
ACT for injury prevention in nurses and aides
This study tests a program called Acceptance and Commitment Therapy (ACT) to help nurses and nursing aides prevent injuries at work. If you work in a long-term care facility in specific areas of the US or Thailand, you may be able to join.
Bowling Green, OhioAges 18 years+ - NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06831838Recruiting
Pain management program for breast cancer survivors with joint pain
This trial tests a cognitive behavioral therapy (CBT) based program to help relieve joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It aims to improve your quality of life and reduce symptoms.
Jacksonville, FloridaAges 18 years+ - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17 - NCT06832852Recruiting
Comparing cost-effective care for muscle and joint pain
This study compares different models of care to find the most cost-effective way to treat common muscle and joint problems (like back, neck, knee, or shoulder pain). It looks at which approach works best for patients with persistent pain to guide future treatment decisions.
Québec, QuebecAges 18–65 - NCT06838793Recruiting
Comparing two nerve block methods for lung surgery
This trial compares two techniques for numbing the chest during lung cancer surgery to see which provides better pain relief. It may help patients recover with less discomfort.
New TerritoriesAges 18–80 - NCT06867757Recruiting
Chronic pain in youth study
This study tests a new way to understand and track chronic pain in young people using real-time feedback. It may help your healthcare team better manage your pain.
Palo Alto, CaliforniaAges 14–24 - NCT06886906Recruiting
Movement and Pain in Older Adults
This study explores how movement and physical activity relate to pain in older adults with muscle or joint pain. It could help you understand your pain patterns and find better ways to manage them.
Indianapolis, IndianaAges 55–85 - NCT06906107Recruiting
Neck pain study: testing a personalized treatment approach
This study is testing a method to see which neck pain patients benefit most from manual therapy and exercise. You may be eligible if you have neck pain (with or without arm symptoms) and have not had recent whiplash, neck surgery, or certain other conditions.
Rochester, MinnesotaAges 18–70
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Common questions
- Are there clinical trials for musculoskeletal?
- Yes. Clin2 currently lists 216 recruiting musculoskeletal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.