Clinical trials
Nephrectomy clinical trials
Below are recruiting nephrectomy clinical trials, each written for real people, not researchers. We’re tracking 59 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07092566RecruitingPhase 3
Pain relief after robotic kidney surgery: R.E.C.K. vs Exparel
This trial tests two different pain-relief medicines (R.E.C.K. and Exparel) given during robotic kidney surgery. It aims to find which works better to control pain after the operation.
Charlotte, North CarolinaAges 18 years+ - NCT07294859Recruiting
Ultrasound to predict kidney function after kidney removal
This trial uses special ultrasound techniques to predict how well your remaining kidney will work after surgery to remove part or all of one kidney. It may help doctors understand your recovery and tailor follow-up care.
Nanjing, JiangsuAges 18 years+ - NCT07396753Recruiting
Nerve block to reduce opioid use after kidney donor surgery
This study tests a nerve block called Transversalis Fascia Plane Block to see if it lowers the amount of strong pain medicine (opioids) needed after a kidney donor surgery. It may help you have less pain and fewer side effects.
Istanbul, ZeytinburnuAges 18–80 - NCT07461090Recruiting
Laparoscopic vs. open kidney removal surgery study
This study compares laparoscopic (keyhole) and open surgery for removing all or part of a kidney. It looks at how well each method works and how much it costs, to help decide which is better for patients with certain kidney conditions or tumors.
Shibīn al Kawm, Shebin ElkomAges 1 year+ - NCT07556536Recruiting
Nerve block comparison for kidney removal surgery pain
This trial tests two different types of numbing injections (nerve blocks) to see which one works better at controlling pain after open kidney removal surgery. You would receive one of these blocks during surgery to help reduce pain and the amount of strong pain medication you need afterward.
Al FayyumAges 18–65 - NCT07560267Recruiting
Ultrasound nerve block for kidney surgery pain relief
This trial tests whether a special nerve-numbing injection in the back (guided by ultrasound imaging) can reduce pain after kidney removal surgery. If it works well, it could help patients recover more comfortably with less need for strong pain medications.
DhakaAges 18–64 - NCT07640282Recruiting
Nerve Blocks for Pain After Kidney Removal Surgery
This trial compares two types of nerve-blocking injections (ESP and EXORA blocks) to reduce pain after laparoscopic kidney removal surgery. The goal is to see which method works better for controlling pain after the procedure.
Istanbul, IstanbulAges 18–80 - NCT06945640Enrolling by invitation
Testing a 3D imaging system for robot kidney surgery
This study tests a new 3D imaging system (RUS NE) to help surgeons perform robot-assisted partial nephrectomy more safely and effectively. If you have a small to medium-sized kidney tumor and are already scheduled for this surgery, the researchers want to compare your outcomes to people who had the standard procedure.
SeoulAges 20–80 - NCT05520151Recruiting
Oral immune-support before kidney or bladder surgery
This trial studies whether an oral immune-modulating product given before major bladder or kidney surgery can lower the risk of postoperative complications. If you’re scheduled for surgery like cystectomy or nephrectomy, it may be an option to help your recovery.
Aulnay-sous-BoisAges 18 years+ - NCT06879912Recruiting
Study of force feedback tools in robot-assisted surgery
This trial tests new force feedback instruments in the da Vinci 5 robot during surgery. It aims to see if they help surgeons perform procedures more precisely for conditions like cancer or other diseases.
Miami, FloridaAges 22 years+ - NCT06401330RecruitingPhase 3
Wilms tumor treatment study for children and young adults
This study is testing different treatments for children and young adults with a type of kidney cancer called Wilms tumor. The treatment you get depends on certain risk factors, like tumor stage and lab results. The goal is to give the right amount of treatment for each person's situation.
Birmingham, AlabamaAges Up to 30 years - NCT07226544RecruitingPhase 2
Ivonescimab before surgery for high-risk kidney cancer
This trial tests giving the drug ivonescimab before surgery for patients with high-risk clear cell kidney cancer. The goal is to see if it can help shrink the tumor and improve outcomes.
Duarte, CaliforniaAges 18 years+ - NCT04182607Recruiting
Looking at outcomes after kidney donation surgery
This review looks at results for kidney donors and recipients who had kidney transplant surgery done either by hand-assisted or robotic methods. It aims to understand how these surgical approaches affect donor and recipient outcomes.
Dallas, TexasAges 18 years+ - NCT04510597RecruitingPhase 3
Immunotherapy plus surgery versus immunotherapy alone for kidney cancer
This study tests whether adding surgery to remove the kidney improves outcomes compared with continuing immunotherapy without surgery. It is for people with metastatic kidney cancer whose disease has not worsened after initial immunotherapy.
Birmingham, AlabamaAges 18 years+ - NCT04617756RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk upper urinary tract cancer
This trial studies whether durvalumab (an immunotherapy) given with chemotherapy before surgery can improve outcomes for people with high-risk cancer in the kidney pelvis or ureter. It is mainly looking at safety and effectiveness in shrinking or controlling the cancer before treatment continues.
Paris, Paris Cx 20Ages 18 years+ - NCT04968990RecruitingPhase 2
New Wilms tumor treated with proton beam abdominal radiation
This trial studies a specific type of radiation (proton beam) given to the abdomen after surgery and/or chemotherapy in children and young people with newly diagnosed Wilms tumor. The goal is to improve cancer control while carefully targeting radiation to the right stage of disease.
Memphis, TennesseeAges Any age - NCT05319015RecruitingPhase 2
Lenvatinib plus pembrolizumab before kidney surgery for IVC tumor
This trial studies lenvatinib and pembrolizumab given before surgery to treat kidney cancer that has grown into a large vein (the IVC) near the liver or heart. The goal is to shrink or control the tumor thrombus and make treatment and surgery more effective and safer.
Dallas, TexasAges 18 years+ - NCT05738694RecruitingPhase 3
Test axitinib plus immunotherapy before kidney cancer surgery
This study tests whether taking axitinib plus an immunotherapy drug (PD-1) before surgery can help people with kidney cancer live longer without the cancer coming back. It’s focused on people who have a higher-risk kidney tumor based on scans and pathology findings.
BeijingAges 18–80 - NCT05810571Recruiting
Pain-control injections compared after open kidney surgery
This study compares two types of pain-control injections placed near the back to see which works better after open kidney (nephrectomy) surgery. If you’re having elective open nephrectomy, it may help doctors choose the safest and most effective way to reduce postoperative pain.
İzmitAges 18–85 - NCT05842044RecruitingPhase 2
NSAID pain medicine after robotic kidney-sparing surgery
This Phase 2 study looks at whether taking an anti-inflammatory pain medicine (an NSAID) after robotic partial nephrectomy is safe and helpful. It may reduce pain while checking for stomach, bleeding, and heart-related side effects after kidney-sparing surgery.
Miami, FloridaAges 18–99 - NCT06147349Recruiting
Kidney cancer observation study
This study follows people with kidney cancer who are scheduled for surgery to remove their tumor. It aims to learn more about the disease and how it behaves over time.
Milan, MIAges 18 years+ - NCT06501079Recruiting
Pain relief study: adding dexamethasone or magnesium to a nerve block for kidney removal
This study compares two different medications (dexamethasone and magnesium) added to a standard painkiller used in a nerve block for patients having one kidney removed. The goal is to find out which combination provides better pain relief after surgery.
CairoAges 18–65 - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT06715878Recruiting
Robot-assisted surgery for small kidney tumors without cutting blood supply
This study tests a new, gentle way to remove small kidney tumors using a robot. The goal is to avoid cutting off blood supply to the kidney and to leave healthy tissue behind. It may help you keep more kidney function while still treating the cancer.
ShanghaiAges 15–80
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Common questions
- Are there clinical trials for nephrectomy?
- Yes. Clin2 currently lists 59 recruiting nephrectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nephrectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nephrectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.