Clinical trials
Neurodegenerative Disorders clinical trials
Below are recruiting neurodegenerative disorders clinical trials, each written for real people, not researchers. We’re tracking 48 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT00271622Recruiting
Screening test for child or adult brain and behavior patterns
This study uses a structured check-up to learn about how someone’s thinking, behavior, and development may differ from typical patterns. It involves an interview and possibly medical, nervous-system, and blood or urine tests to understand what kinds of issues might be present.
Bethesda, MarylandAges 1 month+ - NCT05354622Recruiting
Genetic testing study for inherited leg stiffness
This study looks at genes (DNA) to understand an inherited condition that causes gradually worsening leg stiffness. It may help researchers learn what causes the condition and potentially guide future care.
Boston, MassachusettsAges 1 month–30 years - NCT06672237RecruitingPhase 3
Study of NTLA-2001 for hereditary ATTR amyloidosis with nerve damage
This study is testing a new gene-silencing treatment called NTLA-2001 for people with hereditary ATTR amyloidosis that causes nerve damage. It works by stopping the body from making a faulty protein that builds up and harms nerves.
Buenos AiresAges 18–85 - NCT05474235Recruiting
ALS and motor neuron disease studies for patients, family, and controls
This study looks at people with amyotrophic lateral sclerosis (ALS), people who might have ALS, and also people related to someone with ALS. It may help researchers better understand ALS and related “motor neuron” conditions, and it involves participation that may include blood tests.
Jacksonville, FloridaAges 18 years+ - NCT05929144Recruiting
MRI testing to improve brain scans in neurodegenerative diseases
This study aims to improve MRI scan settings used when studying brain diseases that affect memory and movement. You would be asked to undergo MRI scanning as a healthy volunteer to help optimize the imaging process.
CaenAges 18 years+ - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT07361887Recruiting
Moderate wine and healthy aging study
This study tests whether moderate wine consumption can help healthy aging by looking at tiny particles in your blood after a meal. It may help you understand how wine affects your body's cells.
Seville, SevillaAges 35–36 - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT07314190Enrolling by invitation
Blood tests for brain diseases and mental health conditions
This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.
BarcelonaAges 18 years+ - NCT05875103Recruiting
Brain and language study using a word fluency task
This study looks at how thinking and language work in people with certain brain conditions, using a simple word-finding task and brain scans. It may help researchers better understand what brain changes are linked to different symptoms.
AmiensAges 18 years+ - NCT05597410Recruiting
Study of people at risk for Alzheimer’s in Shanghai
This study follows people who are closely related to someone diagnosed with Alzheimer’s to see who develops memory or brain changes over time. It may help researchers understand risk and early signs, which could guide prevention in families like yours.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07268079Recruiting
Testing a VR app for brain and thinking skills
This study is testing a virtual reality app called VIRADIA to see if it can help check brain and thinking skills. Doctors are looking for people with and without a neurological condition like Parkinson's or multiple sclerosis to take part.
Nitra, Nitra RegionAges 18–80 - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT06755840Recruiting
Sleep breathing problems and multiple health conditions study
This study is for people who may have sleep-related breathing problems (like sleep apnea). It looks at how these issues connect with other health conditions. Participants will do a one-night sleep test and some simple health checks at Xiangya Hospital.
ChangshaAges Any age - NCT07360977Recruiting
Broccoli supplement for Parkinson's and multiple sclerosis
This trial tests a natural compound (from broccoli sprouts) called glucoraphanin, which may help protect brain cells in people with Parkinson's disease or multiple sclerosis. It aims to see if taking this supplement can slow down or improve symptoms.
MessinaAges 1–75 - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07324330Recruiting
Slowing cognitive decline with exercise in iRBD
This study tests if increasing physical activity can help slow down cognitive (thinking) decline in people with iRBD, a sleep disorder that often leads to Parkinson's or dementia. You'll use a smartphone and a FitBit to track your activity and receive coaching.
Bonn, North Rhine West-FaliaAges 50–80 - NCT05443906Recruiting
Home exercise program for people with neurodegenerative conditions
This trial studies whether a home exercise program is safe and helpful for people with certain neurodegenerative conditions, including X-linked adrenoleukodystrophy and DARS2-related disease, as well as some other similar diagnoses. You would be asked to do exercises at home and be assessed on your walking and strength/safety.
Baltimore, MarylandAges 5–75 - NCT06846658Recruiting
Finding early signs of Parkinson's and related diseases
This study looks at cells from the nose, blood, and urine to find early markers for Parkinson's disease, similar conditions, and memory problems linked to Lewy bodies. If you have one of these conditions, joining could help improve early diagnosis.
Sesto Fiorentino, FIAges Any age - NCT07467460Recruiting
Precision medicine trial for Parkinson's and Alzheimer's
This trial uses advanced tools to better diagnose and treat Parkinson's disease and Alzheimer's disease. It aims to personalize care based on your specific symptoms and biomarkers.
PozzilliAges 18 years+ - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT03233646Recruiting
Retina scans in memory and nerve disorders
This study uses pictures of the back of your eye (retinal imaging) to look for differences in people with neurodegenerative diseases and compares them with people without these conditions. It may help researchers understand eye changes that could connect to brain or nerve health.
Durham, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for neurodegenerative disorders?
- Yes. Clin2 currently lists 48 recruiting neurodegenerative disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurodegenerative disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurodegenerative disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.