Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Birmingham, AlabamaAges 18 years+ - NCT05943626Recruiting
Sleep timing changes to improve heart and blood sugar health
This study tests whether changing your sleep habits can improve heart-related health and blood sugar control. You may be asked to follow a sleep schedule and other routines, and outcomes will be measured over time.
Salt Lake City, UtahAges 18–45 - NCT07728669Recruiting
Digital diet app for people on GLP-1 therapy
This study tests a smartphone app that gives dietary advice to people who are overweight or obese and also take a GLP-1 medication (like semaglutide) for weight or diabetes. The app will help you follow a healthy eating plan while using the medication.
AlmatyAges 21–65 - NCT07724340RecruitingPhase 2
Study of AT673 plus semaglutide for type 2 diabetes and weight loss
This study tests a new medication called AT673 combined with semaglutide (Wegovy) to help people with type 2 diabetes and overweight or obesity lose weight and improve blood sugar. It is for people who have tried diet and exercise to lose weight but haven't had success.
Chandler, ArizonaAges 18 years+ - NCT06282952Recruiting
Stool transplant for C-section babies' health
This trial tests whether giving a special stool transplant (fecal microbiota) to healthy babies born by C-section can improve their health. It aims to see if this treatment helps replace good bacteria that are normally passed during a vaginal birth.
OuluAges birth–6 hours - NCT06147973Recruiting
Healthy lifestyle program for teen girls
This study tests a healthy lifestyle program that helps teen girls accept their bodies and make positive changes. It aims to see if this approach can improve weight-related health and well-being.
Philadelphia, PennsylvaniaAges 14–19 - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT03087032RecruitingPhase 4
Liraglutide injections vs insulin for uncontrolled type 2 diabetes
This trial compares two treatment approaches—liraglutide injections versus a specific insulin (glargine) injection—plus meal-time insulin dosing (“bolus”) in adults with overweight/obesity and type 2 diabetes that isn’t well controlled. The goal is to see which option works better and is safer for improving blood sugar.
Xiamen, FujianAges 18–75 - NCT03561766Recruiting
Pregnancy birth-cohort study for early pregnancy participants
This study follows pregnant people from early pregnancy to help researchers better understand health and outcomes over time. It’s mainly for those who plan to receive care and deliver at Shengjing Hospital in the Shenyang area.
Shenyang, LiaoningAges 18 years+ - NCT03574103Recruiting
Testing how fasting affects health in women with excess weight
This study looks at the long-term effects of fasting on the body in women who have a higher-than-average weight. It may help researchers understand potential benefits and risks of fasting, but it also requires you to meet several health and medication rules.
Belo Horizonte, Minas GeraisAges 18–59 - NCT04583514Recruiting
Overfeeding study to see how body fat can expand
This trial studies how your body’s fat tissue changes when you eat extra food for 8 weeks. It may help researchers understand why some people gain more weight than others.
Baton Rouge, LouisianaAges 18–42 - NCT04791371Recruiting
Study how fitness and insulin resistance relate to diabetes
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
Aurora, ColoradoAges 30–55 - NCT04943926Recruiting
Diet changes to help put type 2 diabetes into remission
This study tests whether specific dietary strategies can help people with type 2 diabetes reach remission (better blood sugar without ongoing high medication needs). You may be a good candidate if your diabetes is relatively recent, your weight is above a certain threshold, and your heart and other health conditions are stable.
Bergen, VestlandAges 24–70 - NCT05301413RecruitingPhase 2
Diabetes prevention program tailored for Black adults at risk
This Phase 2 study tests a diabetes-prevention program designed for Black/African American adults, focusing on social factors that can affect health and weight. It aims to help participants lower their chances of developing type 2 diabetes through structured education and tracking.
Kansas City, MissouriAges 18 years+ - NCT05309395RecruitingPhase 3
Food prescriptions to help Latino families eat affordably
This trial tests whether giving free/covered “food prescriptions” helps multigenerational Latino households lose weight by improving diet within a budget. It may help families who want to eat healthier without worrying as much about grocery costs.
Pasadena, CaliforniaAges 2 years+ - NCT05316493RecruitingPhase 2/Phase 3
Weight-loss and progesterone treatments for early uterine lining disease
This trial studies a weight-management approach plus a progesterone-releasing IUD (LNG-IUS) and megestrol to treat endometrial atypical hyperplasia, a high-risk precancer of the uterine lining. It may help shrink or control the abnormal cells while supporting fertility or keeping the uterus.
ShanghaiAges 18–45 - NCT05353504Recruiting
Testing how gut changes affect food choices
This study looks at whether interventions that change your gut bacteria can change how you decide what to eat. It may help researchers understand the gut–brain link behind eating behavior.
LeipzigAges 18–60 - NCT05530538Recruiting
Phone app program to help teens manage weight
This study tests a weight-management app (the BrainWeighve app) for teens. It looks at whether the app is workable and helpful for teens who are motivated to change weight habits.
Los Angeles, CaliforniaAges 14–21 - NCT05619705Recruiting
Health coaching for pregnant women through home visits
This trial tests a structured health-coaching program delivered during home visits to help pregnant people improve health habits during pregnancy. It may help you with support like tracking weight and following a planned coaching routine.
Baltimore, MarylandAges 18 years+ - NCT05632406Recruiting
Breathing training to improve breathing and blood pressure
This study tests whether a breathing device training program can improve breathing and blood pressure. It may help people who have higher blood pressure and may feel out of breath, especially those who have weight-related breathing strain.
Tallahassee, FloridaAges 18–45 - NCT05807594Recruiting
Online program to help manage weight gain during pregnancy
This trial tests an at-home (online) coaching program to help pregnant people gain weight at a healthier rate. It may help you stay on track during pregnancy and understand what changes work best for you.
University Park, PennsylvaniaAges 18–45 - NCT05840497Recruiting
Exercise program to help lower gestational diabetes risk
This trial tests whether a strength and resistance exercise program during pregnancy can help reduce gestational diabetes in people who are overweight or obese. It may help by improving how your body handles sugar during pregnancy.
Pamplona, NavarreAges 18 years+ - NCT05843318Recruiting
Water intake and weight control for adults 50+
This study tests whether adjusting how much plain drinking water you drink can help with weight control in older adults. You may be asked to follow a structured plan and participate in activities as part of the research.
Blacksburg, VirginiaAges 50 years+
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 486 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.