Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05956574Recruiting
Lifestyle coaching program for weight and health changes
This study tests whether a lifestyle and activity program can help people with higher body weight make healthier changes. You may be asked to track your habits on a smartphone and participate in walking and exercise activities.
Augusta, GeorgiaAges 18–40 - NCT05958368Recruiting
Avocado study to improve blood sugar in type 2 diabetes
This study tests whether eating avocados can improve blood sugar control in adults with type 2 diabetes. You may have blood tests and will follow a specific eating plan while your diabetes care continues under your doctor.
Baton Rouge, LouisianaAges 18–65 - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT06069622Recruiting
How a gene affects weight-loss treatment response
This study looks at how a weight-loss medication affects people with obesity who may have a specific gene difference (caveolin-1). It aims to understand why some people respond differently to GLP-1 treatments like semaglutide.
Boston, MassachusettsAges 18 years+ - NCT06076187Recruiting
How older adults digest protein after weight loss surgery
This study looks at how well older adults break down protein after bariatric surgery. It compares people who had surgery one to ten years ago with those who didn't, to understand protein needs.
Leuven, Flemish BrabantAges 18 years+ - NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT06116435Recruiting
Lifestyle program for weight loss and physical activity
This study tests a lifestyle program to help people become more active and lose weight. It compares different types of support to see what works best.
Aurora, ColoradoAges 18–65 - NCT06144593Recruiting
Carb cutting for people with type 2 diabetes
This study looks at whether cutting carbs on certain days can improve metabolism for people with type 2 diabetes. It may help if you have mild to moderate diabetes and are overweight or obese.
HvidovreAges 35–75 - NCT06151015Recruiting
Dietary nitrate and calorie restriction for brain health
This study tests whether eating foods rich in dietary nitrates (like beets) combined with reducing calorie intake improves memory and blood vessel function in older adults.
Nottingham, NottinghamshireAges 60–75 - NCT06244888RecruitingPhase 2
Using new strategies to help maintain weight loss
This study tests a method to help people who have already lost weight keep it off. It uses a control systems engineering approach to provide personalized support.
Providence, Rhode IslandAges 18–70 - NCT06277232Recruiting
Nutrition care for chronic pain patients
This trial tests a nutrition care program for people with chronic pain who are also overweight. You will receive support to improve your diet while attending a pain rehabilitation program.
Linköping, Östergötland CountyAges 18 years+ - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06382298Recruiting
Cottonseed oil vs. similar oil for heart health
This study compares the effects of cottonseed oil versus a similar oil on heart health. It is for people with high cholesterol or who are overweight and want to see if changing cooking oils can improve their cholesterol levels.
Athens, GeorgiaAges 25–75 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+ - NCT06426693Recruiting
Brain training for food cravings
This study tests a brain-training technique called neurofeedback to help reduce food cravings. You'll get MRI scans while learning to control brain activity related to cravings.
New Haven, ConnecticutAges 18–60 - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06477705Recruiting
Energy cost of 1-hour football training for men with metabolic syndrome
This trial measures how much energy you burn during one hour of football training. It aims to understand exercise energy use in people with metabolic syndrome, which could help guide future exercise programs.
TrikalaAges 40–60 - NCT06481020Recruiting
Plant sterols for heart health in overweight adults
This study tests whether plant sterols (natural compounds found in plants) can help improve cholesterol and other heart health markers. If you are overweight and have high LDL cholesterol, you may be able to join this study to see if adding plant sterols to your diet helps.
ValenciaAges 18–80 - NCT05234125Recruiting
Lifestyle counseling during pregnancy for African American women
This trial tests a better lifestyle counseling program during pregnancy to help improve health—especially for women who started pregnancy at a higher weight. It may help you learn practical changes for a healthier pregnancy and outcomes.
Chicago, IllinoisAges 18–40 - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT06491537Recruiting
Time-restricted eating for losing weight after having a baby
This study tests whether eating only during a specific daily window (time-restricted eating) helps new moms lose weight. It may be an option if you are 6 to 16 weeks postpartum and have a body mass index (BMI) of 25 or higher.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 486 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.