Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 494 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07504068Recruiting
Exercise and supplement for metabolic health in overweight adults
This trial tests whether a combination of physical exercise and a nutritional supplement can improve body composition, metabolism, and overall health in adults who are overweight and have early signs of metabolic problems. It may help you if you are looking for a non-drug approach to boost your health.
Valencia, ValenciaAges 50–65 - NCT03087032RecruitingPhase 4
Liraglutide injections vs insulin for uncontrolled type 2 diabetes
This trial compares two treatment approaches—liraglutide injections versus a specific insulin (glargine) injection—plus meal-time insulin dosing (“bolus”) in adults with overweight/obesity and type 2 diabetes that isn’t well controlled. The goal is to see which option works better and is safer for improving blood sugar.
Xiamen, FujianAges 18–75 - NCT06653530Recruiting
Thread embedding acupuncture for weight loss
This trial tests a type of acupuncture called thread embedding to help with weight loss. It's for people who haven't had success with diet and exercise alone and have a higher body weight or weight-related health issues.
Beijing, Beijing MunicipalityAges 18–75 - NCT06594796Recruiting
Lifestyle program for back pain and weight
This trial tests a combined exercise and lifestyle program for people with long-lasting low back pain who are overweight or have obesity. The program is delivered by physical therapists and aims to improve physical function and reduce pain.
AmsterdamAges 18 years+ - NCT06668077Recruiting
Impulse control training and brain stimulation for weight loss
This study tests whether a computer-based training to improve impulse control, combined with a gentle brain stimulation technique (called iTBS), can help people with excess weight. It also looks at how these treatments affect the brain using MRI scans.
GranadaAges 18–60 - NCT07395973Recruiting
Ketogenic drink and muscle health in older adults
This study tests whether a special ketogenic drink taken for 4 weeks can improve how your body uses energy and help maintain muscle health. It may be a good option if you are between 60 and 80, overweight but not diabetic, and not very active.
MaastrichtAges 60–80 - NCT05956574Recruiting
Lifestyle coaching program for weight and health changes
This study tests whether a lifestyle and activity program can help people with higher body weight make healthier changes. You may be asked to track your habits on a smartphone and participate in walking and exercise activities.
Augusta, GeorgiaAges 18–40 - NCT07376655Recruiting
Test of a health app for lifestyle and wellbeing
This study tests whether using the Thrive AI Health app can help improve daily habits and quality of life for people at high risk for chronic diseases like diabetes. If you're 40 or older and have a higher BMI or diabetes risk, you might be eligible.
New Haven, ConnecticutAges 40 years+ - NCT06853652Recruiting
Protein needs after weight-loss surgery
This study looks at how much protein you need after Roux-en-Y gastric bypass (RYGB) surgery. It will help find the right amount of protein to keep your body healthy after weight-loss surgery.
LeuvenAges 18–65 - NCT07324447Recruiting
Supervised exercise after bariatric surgery to protect muscles and bones
This trial is testing whether a supervised exercise program after bariatric surgery helps protect your muscle mass and bone density. It is for people who are eligible for gastric bypass or sleeve surgery and can commit to an exercise routine near Seville.
Seville, SevillaAges 18 years+ - NCT07299942Recruiting
Beta-glucan supplement for weight loss in women
This trial tests whether taking a beta-glucan supplement (a type of fiber) during a calorie- and carb-restricted diet helps with losing body weight and fat, controlling appetite, and managing hunger hormones. It is for healthy women who are overweight or obese and not following a special diet.
GlasgowAges 18–60 - NCT07292441RecruitingPhase 3
Long-term weight loss study for trial participants
This study is for people who finished a previous weight loss trial and want to continue treatment with an injectable medication GZR18. It tests how well the medicine works over a longer period.
Beijing, Beijing MunicipalityAges 18–75 - NCT03574103Recruiting
Testing how fasting affects health in women with excess weight
This study looks at the long-term effects of fasting on the body in women who have a higher-than-average weight. It may help researchers understand potential benefits and risks of fasting, but it also requires you to meet several health and medication rules.
Belo Horizonte, Minas GeraisAges 18–59 - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT06600100Recruiting
Inhibitory control training for weight management
This trial tests an online training program designed to improve your ability to resist cravings and make healthier choices. It may help you lose weight by strengthening the part of your brain that controls impulses.
GranadaAges 18–60 - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT07246408Recruiting
Cottonseed oil study for heart health
This study tests how taking cottonseed oil at certain times affects heart disease risk. It may help people with high cholesterol or who are overweight.
Athens, GeorgiaAges 25–75 - NCT07230496RecruitingPhase 1
Safety study of an investigational weight-management drug
This study is testing a new investigational drug, either alone or combined with another drug, to see how safe it is and how the body processes it. It is for healthy people who are overweight or obese, and results may help in developing future treatments for weight management.
Sydney, New South WalesAges 18–75 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT07237750Recruiting
Weight loss trial: endoscopy procedure vs lifestyle changes
This study compares a new endoscopic procedure (a stomach tightening treatment done through a tube in your mouth) with a structured diet and exercise program to help with weight loss. It is for Asian adults who have tried and failed to lose weight before.
Beijing, Beijing MunicipalityAges 18–65 - NCT06859853RecruitingPhase 1
MWN109 injection safety study in healthy volunteers
This trial tests an investigational injection called MWN109 to see if it is safe and how the body processes it. It is for healthy adults only, and the results will help decide if the drug should be tested in people with medical conditions.
Melbourne, VictoriaAges 18–50 - NCT07202884RecruitingPhase 3
Orforglipron for Women with Stress Incontinence and Overweight
This study tests an oral medication called orforglipron to see if it helps women with stress urinary incontinence who are also overweight or have obesity. The medicine may reduce leaking episodes and also help with weight loss.
Birmingham, AlabamaAges 18 years+ - NCT05309395RecruitingPhase 3
Food prescriptions to help Latino families eat affordably
This trial tests whether giving free/covered “food prescriptions” helps multigenerational Latino households lose weight by improving diet within a budget. It may help families who want to eat healthier without worrying as much about grocery costs.
Pasadena, CaliforniaAges 2 years+ - NCT07180316Recruiting
Comparing robotic vs. laparoscopic surgery for weight loss revision
This trial compares two types of surgery (robotic and laparoscopic) to see which leads to fewer problems after a second weight-loss operation. It is for people who need to revise their first bariatric surgery to a Roux-en-Y gastric bypass.
LyonAges 18–70
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 494 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.