Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07317115Recruiting
Comparing a new surgery to a diabetes drug for weight loss
This trial compares a new surgical procedure (duodeno-ileostomy) to a medication (semaglutide) for people with obesity and type 2 diabetes. It aims to see which approach works better for weight loss and blood sugar control.
Westmount, QuebecAges 18 years+ - NCT05844644RecruitingPhase 2
Golo plan for weight and blood sugar in prediabetes
This trial tests whether the Golo for Life plan (with a release supplement) can improve blood sugar and help with weight in adults who have prediabetes or type 2 diabetes. If you join, you’ll follow the program and attend clinic visits while your health, diet, and weight are tracked.
LaSalle, OntarioAges 18–75 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Phoenix, ArizonaAges 18 years+ - NCT05124808Recruiting
Tight blood sugar targets in pregnant women with gestational diabetes
This study compares a tighter blood sugar goal versus a standard goal in pregnant people with gestational diabetes who are also overweight or obese. It may help find whether stricter blood sugar control improves pregnancy outcomes.
Birmingham, AlabamaAges 18–45 - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Avondale, ArizonaAges 18 years+ - NCT07407348RecruitingPhase 1
Comparing Two Forms of Survodutide in People with Overweight or Obesity
This trial compares how two different forms of the study drug survodutide are absorbed by the body in people with overweight or obesity. It helps doctors understand which version works better.
NottinghamAges 18–65 - NCT07776678Recruiting
Body fat and muscle measurement study
This study uses advanced body scans (like MRI and DXA) to better measure body fat and muscle. It may help improve how obesity is diagnosed and treated.
Phoenix, ArizonaAges 18 years+ - NCT07231484Recruiting
Grape study for immune and gut health in obesity
This trial tests if eating grapes every day for 4 weeks can improve your immune system and gut health. It is designed for adults with obesity who are willing to keep their diet and activity stable during the study.
Columbia, MissouriAges 18–60 - NCT07559136RecruitingPhase 1
Safety study of HRS9531 injection for teen obesity
This study tests whether a new injectable medication called HRS9531 is safe and well-tolerated in teenagers aged 12–17 with obesity. Researchers will monitor how your body handles the medication and whether it affects your weight.
Wuhan, HubeiAges 12–18 - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT05107908Recruiting
Test brain and behavior effects of a hidden message on eating
This study tests whether a subtle “priming” approach can improve eating behaviors in people with obesity. It also looks at brain activity during the process to understand how the approach may work.
Aurora, ColoradoAges 18–65 - NCT07165548Recruiting
Testing a special diet for weight and health in obesity
This trial tests whether a special diet with foods that make you feel full can help people with overweight or obesity lose weight and improve their heart, metabolic, and joint health.
Pamplona, NavarreAges 18–65 - NCT07368842Recruiting
Scalp hair study in severe obesity
This study looks at chemicals in scalp hair from people with severe obesity to learn more about the condition. Participants must be planning to have weight-loss surgery.
SingaporeAges 21–70 - NCT07414043Recruiting
Understanding obesity drug treatments
This study aims to better understand patients who are prescribed medications like Orlistat, Mysimba, Saxenda, Wegovy, or Mounjaro for obesity. It will help doctors improve treatments for you.
Bologna, BolognaAges 12 years+ - NCT07515547Recruiting
How Obesity Affects the Body Over Time
This research study examines how excess weight impacts your body's health and function, both in the short term and long term. Researchers want to understand the physical changes that happen with obesity and how your body responds.
Montreal, QuebecAges 25–40 - NCT07570758RecruitingPhase 2
Testing ERX1000 to Help Adults Manage Obesity
This study tests whether a new medication called ERX1000 is safe and well-tolerated in adults with obesity. The trial will help doctors understand if this treatment could be helpful for weight management.
Louisville, KentuckyAges 18–60 - NCT07444736Enrolling by invitation
Exercise with blood flow restriction for adults with obesity
This study tests if adding blood flow restriction to resistance training can improve muscle strength and health in adults with obesity. It may help you build muscle more efficiently with lighter weights.
Tlajomulco de Zúñiga, JaliscoAges 18–30 - NCT07283978Enrolling by invitation
Testing digital tools for weight management
This study looks at using digital tools like apps to help manage weight. It's for people in a specialized weight management program in South East London.
London, Greater LondonAges 18 years+ - NCT07283406Enrolling by invitation
High-intensity interval training for young adults with obesity
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart health and fitness in young adults with obesity. You would participate in a supervised exercise program to see if it helps lower your risk of future health problems.
Guadalajara, JaliscoAges 18–35 - NCT06903455Enrolling by invitation
Dance program for heart health in Indigenous women
This study tests a culturally designed dance program for Indigenous women who are overweight or obese. It aims to improve heart health by making exercise fun and meaningful.
Padre Las Casas, AraucaniaAges 18–80 - NCT05097365Enrolling by invitation
Testing a methyl-donor supplement to study lupus metabolism
This study looks at whether a “methyl-donor” nutrient supplement changes metabolism (methylation) in people with lupus who are also in the childbearing age range and have low-to-moderate disease activity. It may help researchers understand why lupus acts differently in some people and how diet-related pathways could affect symptoms.
São PauloAges 18–45 - NCT07018544Enrolling by invitation
Wegovy safety and effectiveness study in Korea
This study watches how Wegovy (semaglutide) works and its side effects when given by doctors to patients with obesity or overweight in South Korea. It is not testing a new drug, but collecting information from routine care.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT07165431Recruiting
Postbiotic supplement study for overweight and obesity
This study tests whether taking a daily postbiotic gummy for 12 weeks can improve body composition and metabolic health in people with overweight or obesity. It may help if you have stable weight and no major health conditions like diabetes.
Pamplona, NavarreAges 18–70
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 486 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.