Clinical trials · Missouri
Obesity clinical trials in Missouri
We’re tracking 54 recruiting obesity studies with a site in Missouri — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Missouri
- NCT07639021RecruitingPhase 2
Testing Different Dose Schedules of a New Weight Loss Medicine
This study tests a new injectable medication (NNC0662-0419) designed to help people with obesity lose weight. Researchers are comparing different ways of increasing the dose to find the safest and most effective approach.
City of Saint Peters, MissouriAges 18 years+ - NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity
This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.
St Louis, MissouriAges 50–75 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06571474Recruiting
Fat Cell Function in Obesity and Metabolism Study
This study looks at how a type of immune cell (macrophage) in fat tissue processes lipids, and how that affects metabolism in people with different body weights. It may help us understand why some people with obesity develop diabetes and fatty liver while others do not.
Columbia, MissouriAges 18–70 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
City of Saint Peters, MissouriAges 18–75 - NCT06745063RecruitingPhase 2
Study of a diabetes drug to reduce artery stiffness in veterans with obesity
This trial tests whether an SGLT2 inhibitor (a type of diabetes medication) can help reduce stiffness in the arteries of veterans who have obesity. If you are a veteran aged 30-60 with a BMI of 30-45 and have stiffer arteries than expected for your age, this study might be an option.
Columbia, MissouriAges 30–60 - NCT07083557Recruiting
Validation study for lab tests on hormones and metabolism
This study checks if lab tests used for hormone, heart, metabolism, and muscle disorders are accurate and reliable. You might be eligible if you are an adult with a body mass index between 16 and 60.
Columbia, MissouriAges 18–100 - NCT07142707RecruitingPhase 1
Testing a new obesity drug for safety and effects
This study tests an investigational medication called MBX 4291 for adults with obesity. It aims to see if the drug is safe and how it works in the body, which could lead to a new weight-loss treatment option.
Kansas City, MissouriAges 18–65 - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Kansas City, MissouriAges 18–99 - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Chesterfield, MissouriAges 18 years+ - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Kansas City, MissouriAges 18–99 - NCT07564414RecruitingPhase 3
Weight Loss Study Comparing Two Doses of CagriSema
This study tests whether a new combination medication called CagriSema (in two different doses) helps people with obesity lose weight. You may qualify if you're 18 or older, have a BMI of 35 or higher, and either don't have type 2 diabetes or have it well-controlled.
Chesterfield, MissouriAges 18 years+ - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
City of Saint Peters, MissouriAges 18–75 - NCT07656727RecruitingPhase 2
A study of BGE-102 for obesity and heart risk
This trial tests an experimental drug called BGE-102 in people with obesity and signs of inflammation. It aims to see if the drug can help reduce body weight and improve heart health. Participants must be willing to keep a stable diet and exercise routine.
Kansas City, MissouriAges 18 years+ - NCT07770841RecruitingPhase 3
Oral medication for weight loss study
This study tests an oral medicine (semaglutide) to see if it helps adults with excess weight lose weight. It might offer an easier, pill-based treatment option for weight management.
City of Saint Peters, MissouriAges 18 years+ - NCT06830096Recruiting
Understanding a key cell channel in type 2 diabetes
This study looks at how a specific channel in your cells (called the KATP channel) affects blood sugar control in people with and without type 2 diabetes. It aims to understand why some people develop diabetes and how to better treat it.
St Louis, MissouriAges 18–65 - NCT07282340RecruitingPhase 2
Phentermine for weight loss in teens
This study tests a medicine called phentermine to help teens ages 12 to 17 with obesity lose weight. It will check if the medicine is safe and works well for teenagers.
Kansas City, MissouriAges 12–17 - NCT07153471RecruitingPhase 3
A study of an experimental pill for weight loss and knee arthritis
This trial tests an investigational medication (orforglipron) to see if it helps people with knee arthritis lose weight. You may qualify if you have overweight or obesity and have tried dieting before without lasting success.
City of Saint Peters, MissouriAges 18 years+ - NCT07667803RecruitingPhase 3
Study of elecoglipron for weight loss in obesity or overweight
This trial tests an investigational drug called elecoglipron to see if it helps people with obesity or overweight lose weight. It may be an option if you have a high body mass index or weight-related health issues like high blood pressure or prediabetes.
Kansas City, MissouriAges 18 years+ - NCT06397729Recruiting
Testing a new tool to support healthy habits in rural clinics
This study is testing a new way to help people improve their heart health by making healthy changes in their daily habits. It focuses on patients in rural primary care clinics who are at higher risk because of their weight.
St Louis, MissouriAges 18–64 - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT05301413RecruitingPhase 2
Diabetes prevention program tailored for Black adults at risk
This Phase 2 study tests a diabetes-prevention program designed for Black/African American adults, focusing on social factors that can affect health and weight. It aims to help participants lower their chances of developing type 2 diabetes through structured education and tracking.
Kansas City, MissouriAges 18 years+ - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+
Obesity trials by city in Missouri
Where these studies are running in Missouri
Institutions with a site for the recruiting obesity studies listed above.
- StudyMetrix Research · 5 studies
- Washington University in St. Louis · 5 studies
- Ellis Fischel Cancer Center / MU Health - University Hospital · 4 studies
- Clinvest Headlands LLC · 3 studies
- Alliance for Multispecialty Research (AMR) - Kansas City · 2 studies
- Clinical Research Professionals · 2 studies
- Amicis Centers of Clinical Research
- Children's Mercy Kansas City
What taking part in a obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Obesity trials in other states
Common questions
- Are there obesity clinical trials in Missouri?
- Yes. We're currently tracking 54 recruiting obesity studies with a site in Missouri, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a obesity study in Missouri?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Missouri to take part?
- Not necessarily. These studies have a site in Missouri, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New obesity studies open in Missouri regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.