Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06716125Recruiting
Lifestyle changes for obese men with sexual and hearing issues
This trial tests whether lifestyle changes can help obese men who have both sexual difficulties and ringing in the ears. It might improve your overall health and these symptoms.
Dokki, Giza GovernorateAges 35–45 - NCT06719011RecruitingPhase 1
Study of an experimental drug for men with overweight or obesity
This trial tests an investigational drug called NNC0174-1213 to see how it works in men with overweight or mild obesity. It may help you manage your weight if you meet the health requirements.
San Antonio, TexasAges 18–55 - NCT06720246Recruiting
Weight loss surgery and liraglutide study on thinking and long-term weight
This trial tests whether bariatric surgery or the drug liraglutide helps people with obesity lose weight and keep it off by looking at how it affects your thinking and behavior. It might help you understand which treatment works best for long-term success.
Milan, MilanAges 20–60 - NCT06721507RecruitingPhase 4
Tirzepatide after weight loss surgery
This study tests whether giving tirzepatide (a medicine that helps with weight and blood sugar) right after weight loss surgery can improve results. It is for people who are already scheduled for sleeve gastrectomy or gastric bypass at UK HealthCare.
Lexington, KentuckyAges 18 years+ - NCT06727500Recruiting
Exercise training for kids with obesity
This trial tests whether two types of exercise training (high-intensity interval training or a mix of HIIT and jumping exercises) improve muscle and tendon health in children and teenagers with obesity. It looks at how results differ based on whether kids are before or after their growth spurt.
SantiagoAges 7–17 - NCT06729203Recruiting
Ultrasound for belly fat and insulin resistance in women
This trial tests if ultrasound cavitation—a non-invasive treatment that uses sound waves to break down fat—can help lower insulin resistance in women with central obesity (fat around the belly). It's a possible option if you have insulin resistance and are not taking diabetes medication.
Giza, Giza GovernorateAges 25–40 - NCT06734273RecruitingEarly Phase 1
Sleeve gastrectomy with tirzepatide for weight loss
This trial compares getting a sleeve gastrectomy alone versus getting it along with tirzepatide (a medicine that helps with weight loss and diabetes) to see if combining them leads to more weight loss. It may help people who are having their first sleeve gastrectomy.
Chicago, IllinoisAges 18–65 - NCT06736028Recruiting
Ketogenic diet for weight loss maintenance in obesity
This study tests whether a ketogenic diet helps people with obesity keep weight off by changing how your body burns energy and controls appetite. You will follow a low-carb, high-fat diet and be monitored for several months.
Birmingham, AlabamaAges 18–65 - NCT06739473RecruitingPhase 4
How obesity affects glucose use in the body
This trial looks at how the body uses sugar (glucose) for energy in people with and without obesity. Results could help find better treatments for metabolic conditions.
TurkuAges 20–60 - NCT06742112Recruiting
Arm and Breathing Test for People Who Are Overweight
This study looks at how well people who are overweight or obese can use their arms and breathe while performing a 6-minute pegboard and ring test. Researchers want to see if this test can help measure physical function in this group.
KırşehirAges 18–65 - NCT06742710RecruitingPhase 4
Liraglutide for obese infertility in PCOS
This trial tests if liraglutide, a weight-loss medication, can help obese women with PCOS who have a frozen embryo achieve pregnancy. It aims to improve fertility outcomes by aiding weight loss before embryo transfer.
Beijing, Beijing MunicipalityAges 20–40 - NCT06745063RecruitingPhase 2
Study of a diabetes drug to reduce artery stiffness in veterans with obesity
This trial tests whether an SGLT2 inhibitor (a type of diabetes medication) can help reduce stiffness in the arteries of veterans who have obesity. If you are a veteran aged 30-60 with a BMI of 30-45 and have stiffer arteries than expected for your age, this study might be an option.
Columbia, MissouriAges 30–60 - NCT06752018Recruiting
Inflammation, heart disease, and diabetes study
This study looks at how inflammation affects heart disease and diabetes. It may help find new ways to prevent or treat these conditions.
AarhusAges 18 years+ - NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT06759623Recruiting
Lung function and anesthesia in bariatric surgery
This study checks how well your lungs work after you receive anesthesia (sleep medicine) for weight-loss surgery. It will help doctors choose the best anesthetic for people with obesity.
GdanskAges 18 years+ - NCT06760546RecruitingPhase 3
Testing setmelanotide for weight gain after brain injury
This trial tests a daily injection called setmelanotide to see if it can help people who have gained weight due to a brain injury or condition affecting the hypothalamus. It may help reduce hunger and support weight loss.
Birmingham, AlabamaAges 4 years+ - NCT06770049Recruiting
Personalized lifestyle program for weight loss in obesity
This study tests a lifestyle program tailored to your biology or behavior to help with weight loss. It is for adults with obesity who haven't had weight loss surgery or used certain weight loss medications recently.
Rochester, MinnesotaAges 18–65 - NCT06778850RecruitingPhase 1/Phase 2
Study of MDR-001 tablet for overweight or obese adults
This study tests a new tablet called MDR-001 for people who are overweight or obese. Researchers want to see if it is safe and helps with weight loss. You would take the tablet in different doses over several weeks.
Changchun, JilinAges 18–55 - NCT06782139RecruitingPhase 4
Enavogliflozin for heart health in obesity and diabetes
This trial tests if Enavogliflozin, a medication for diabetes, can improve blood flow in the small vessels of the heart and overall heart function in people with obesity or diabetes. You may join if you have obesity or diabetes and have had a recent heart test.
SeoulAges 20–79 - NCT06786052RecruitingPhase 2
Study on after-meal energy in adults 50–70
This trial studies how a probiotic supplement affects energy use after meals in adults aged 50–70 who are overweight. You'll take either the probiotic or a placebo for several weeks.
Pierre-Bénite, Auvergne-Rhône-AlpesAges 50–70 - NCT06789965Recruiting
Comparing two weight loss surgeries for severe obesity
This trial compares two different surgical techniques for people with severe obesity (BMI 40-50) to see which works better. It is for those who are good candidates for bariatric (weight loss) surgery.
Barcelona, BarcelonaAges 18–60 - NCT06790160Recruiting
Study of weight-loss medication effects on body composition
This trial looks at how two weight-loss medications, semaglutide and tirzepatide, affect your body's fat and muscle. It may help you understand if these medications improve your overall health beyond just weight loss.
Lubbock, TexasAges 18 years+ - NCT06790225Recruiting
A study on a gut hormone and bone health
This trial looks at how a natural gut hormone (GIP) affects bone remodeling in healthy people. If you are healthy, you may help us understand how this hormone works on bone cells.
EsbjergAges 18–40 - NCT06790329Recruiting
Weight loss trial using stomach stapling and surface ablation
This trial tests a combined procedure that uses stomach stapling (endoscopic sleeve gastroplasty) plus ablation of the stomach lining to help with weight loss. It is for people with obesity who have not been able to lose weight with diet, exercise, or medication alone.
ShatinAges 18–70
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.