Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07103382Recruiting
Testing if a clay mineral helps with weight loss in obesity
This study tests if a natural clay mineral called attapulgite can help people with obesity or overweight and type 2 diabetes lose weight. It aims to see if it is safe and effective.
Changsha, HunanAges 18–60 - NCT07101939RecruitingPhase 2
Studying a medicine to preserve muscle during weight loss
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
BelgradeAges 18–75 - NCT07098663RecruitingPhase 2
Study of MKP10241 for weight loss and diabetes control
This study tests an investigational drug called MKP10241 in healthy people, people with obesity, and people with type 2 diabetes. It aims to see how the drug affects blood sugar, weight, and overall safety. It may be an option if you have obesity or type 2 diabetes managed by diet and/or metformin.
Bayswater, VictoriaAges 18–60 - NCT06971159Recruiting
Vibration therapy and osteopathic care for obesity
This study tests whether gentle whole-body vibration therapy and osteopathic manual treatment (hands-on adjustments) can help people with obesity. It aims to see if these treatments improve weight-related health and well-being.
Rio de Janeiro, Rio de JaneiroAges 18–65 - NCT06363253Recruiting
Gut bacteria study in obesity and muscle loss
This study looks at the bacteria in your gut (the microbiome) to understand how they relate to obesity and muscle loss. Researchers will collect stool samples to analyze the gut bacteria, which may help find new ways to treat metabolic diseases.
SingaporeAges 21–99 - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT07087808Recruiting
Family health program for teens with obesity in rural areas
This trial tests a virtual family intervention to help teens ages 12-17 with obesity and their primary caregiver (who is also overweight) improve health habits together. It's designed for families living in rural communities who both have a smartphone.
Charleston, South CarolinaAges 12–17 - NCT07091500Recruiting
Exercise and a weight-loss drug for people with obesity
This trial tests whether combining a GLP-1 medication (a type of diabetes drug that also helps with weight loss) with an exercise program can improve physical function in people with obesity. If you are obese and have trouble with daily activities, this study may help you become more mobile and healthier.
St Louis, MissouriAges 50–75 - NCT07093502Recruiting
Predicting outcomes after weight-loss surgery for severe obesity
This study is creating a system to predict how well people do after weight-loss surgery for severe obesity. It focuses on patients getting either a sleeve gastrectomy or a gastric bypass and aims to improve recovery and long-term results.
Changsha, HunanAges 18–50 - NCT07081152Recruiting
Iron absorption and losses in young South African women
This study looks at how well young South African women absorb iron and how much iron they lose, comparing women with healthy weight to women with overweight or obesity. It aims to learn if body weight affects iron balance.
Potchefstroom, North WestAges 18–35 - NCT07083557Recruiting
Validation study for lab tests on hormones and metabolism
This study checks if lab tests used for hormone, heart, metabolism, and muscle disorders are accurate and reliable. You might be eligible if you are an adult with a body mass index between 16 and 60.
Columbia, MissouriAges 18–100 - NCT06983431Recruiting
Digital health program for weight management
This study uses a smartphone app and a wearable device to help you manage your weight and health risks. It is for people with a body mass index (BMI) between 27 and 42 who are ready to make healthy changes.
Bratislava, Bratislava RegionAges 25–65 - NCT07065552RecruitingEarly Phase 1
Tirzepatide for weight-linked endometrial cancer
This trial tests if the weight-loss drug tirzepatide can help people with obesity-related endometrial cancer before their hysterectomy. It may improve surgical outcomes and overall health.
Chapel Hill, North CarolinaAges 18 years+ - NCT07057453Recruiting
National childhood obesity prevention program for kids
This program helps children ages 6–11 who are overweight (but not obese) learn healthy habits to prevent obesity. It focuses on lifestyle changes and does not involve any medication or surgery.
Prague, CzechiaAges 6–11 - NCT07057674RecruitingPhase 1
Study of HS-20094 in overweight or obese adults
This study tests a new medication called HS-20094 for people who are overweight or have obesity. It is designed to help with weight loss and will last for several months to see how safe and effective the medicine is.
Qingdao, ShandongAges 18–65 - NCT07057310Enrolling by invitationPhase 4
Weight Loss Drug for Postmenopausal Women With Obesity
This study tests a GLP-1 agonist medication (like Ozempic) to help postmenopausal women lose weight and improve physical and blood vessel health. It focuses on women aged 46–60 with obesity.
Jacksonville, FloridaAges 46–60 - NCT07062315Enrolling by invitation
Eating at the right time for belly fat reduction
This study tests a type of intermittent fasting where you eat only during a certain window that matches your body clock. The goal is to see if this helps reduce belly fat and improve metabolic health in people who are not very active and carry extra weight around the middle.
Hong KongAges 18–65 - NCT07058207Recruiting
Weight management program for obese cancer patients in treatment
This study offers a weight management program for people with obesity who are undergoing active cancer treatment (chemo or radiation) for a solid tumor. It aims to help you manage your weight while you fight cancer, and requires living in the Barcelona area.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT06987279Recruiting
Probiotics for hormone balance in overweight women
This trial tests whether a specific probiotic, Lactobacillus plantarum, can help regulate hormones in overweight women. It involves taking daily probiotic capsules and providing samples over a period of time.
Zhengzhou, HenanAges 18–40 - NCT07052539Recruiting
Kidney disease in heart failure with obesity
This study looks at how kidney disease relates to a type of heart failure (called HFpEF) that often happens in people with obesity. It will help doctors understand this connection better.
Jackson, MississippiAges 18–75 - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Daphne, AlabamaAges 45–99 - NCT07036601RecruitingPhase 2
Study of THDBH120 for weight loss in overweight or obese adults
This trial tests an injection called THDBH120 to help people who are overweight or obese lose weight. You may qualify if you have a BMI of 28 or higher, or a BMI of 24 to 28 with a weight-related health issue like prediabetes or high blood pressure, and you have been exercising and eating healthy for the past 3 months.
ChangshaAges 18–75 - NCT07037459RecruitingPhase 3
A study of a new drug for heart failure with obesity
This trial tests a medication called maridebart cafraglutide for people with heart failure (where the heart doesn't pump as well as it should) and obesity. The goal is to see if it can help improve symptoms and outcomes.
Birmingham, AlabamaAges 18–99
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.