Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06800872Recruiting
Vibration therapy for weight loss in teens
This trial tests if whole body vibration can help teenagers with obesity burn more energy while staying in a hospital program. It may offer an extra tool to support weight management.
Oggebbio, VerbaniaAges 13–18 - NCT06800911Recruiting
Metacognitive beliefs in obesity
This study explores how thinking patterns and beliefs about one's own thoughts may be linked to obesity. It aims to understand the role of metacognition in people with severe obesity.
Oggebbio, VerbaniaAges 18–65 - NCT06801496Recruiting
Stomach stent for weight regain after sleeve gastrectomy
This trial is testing a special stomach stent (called a gastric bypass stent) to help people who regained weight after a sleeve gastrectomy. If you've had a sleeve gastrectomy and your BMI is 27.5 or higher, this study might help you lose weight again without another surgery.
BeijingAges 16–65 - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06815978Recruiting
Diagnosing obesity-related muscle loss
This study tests a new tool to diagnose muscle loss in people with obesity. It may help doctors better identify and treat this condition.
Rome, RMAges 18 years+ - NCT06817863RecruitingPhase 1/Phase 2
Mobile app for binge eating and weight loss
This study tests a self-guided mobile app (iPhone or Android) to help adults with binge eating and obesity. It aims to see if the app can reduce binge eating episodes and support weight management.
Philadelphia, PennsylvaniaAges 18–70 - NCT06820099RecruitingPhase 2
A drug for heart failure with obesity
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06822504Recruiting
Sarcopenic obesity in COPD: a prevalence study
This study looks at how common it is to have both COPD (a chronic lung disease) and sarcopenic obesity (loss of muscle with excess body fat). By joining, you'll help doctors understand this condition better and may get a full health check-up.
Roma, RomaAges 40–100 - NCT06830343RecruitingPhase 1
Safety study of SYH9017 for overweight and obesity
This study tests a new medication called SYH9017 for people who are overweight or have obesity. It aims to see how safe the drug is, how well it is tolerated, and how the body processes it. Participants will receive either the drug or a placebo and be monitored closely.
Beijing, Beijing MunicipalityAges 18–60 - NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT06842186RecruitingPhase 1/Phase 2
Study of WVE-007 for overweight or obesity
This trial tests an experimental drug called WVE-007 for people who are overweight or have obesity. It aims to help with weight loss and is looking at both a group without diabetes and a group with prediabetes or type 2 diabetes.
Baltimore, MarylandAges 18–60 - NCT06847373Recruiting
Vitamin D for teens with obesity
This study is testing whether vitamin D supplements can help teens with obesity. It is open to participants aged 10 to 18 who live in Mexico City and have obesity based on their BMI.
MéxicoAges 10–18 - NCT06852391RecruitingPhase 4
Weight loss program with or without semaglutide for teens with obesity
This trial studies how the body adapts to weight loss in teens with obesity. You will either get a behavioral lifestyle program alone or with a weight loss medication called semaglutide.
Hamilton, OntarioAges 12–17 - NCT06855251Recruiting
Sensing inner body states in obesity
This trial explores how people with obesity sense signals from their own body (like heartbeat or fullness). Understanding this connection could help develop better treatments.
Piancavallo, VCOAges 18–55 - NCT06857942RecruitingPhase 4
Tirzepatide added to ixekizumab for psoriasis and weight issues
This trial tests whether adding tirzepatide (a weight-loss and diabetes drug) to ixekizumab (a psoriasis treatment) helps people with moderate-to-severe psoriasis who are overweight or have obesity. It is for those already taking ixekizumab for about 3 months.
Phoenix, ArizonaAges 18 years+ - NCT06857929Recruiting
Nutrition study for metabolic syndrome
This study tests whether a personalized nutrition plan can improve health and lower the risk of chronic diseases like diabetes and heart disease in middle-aged adults with metabolic syndrome.
Madrid, MadridAges 30–50 - NCT06861868Recruiting
Brain and behavior's role in childhood obesity
This study looks at how the brain and behavior contribute to obesity from infancy through childhood. It may help researchers understand why some children develop obesity and how to prevent it.
Baltimore, MarylandAges 7–12 - NCT06862908RecruitingPhase 2
Study of IBI362 for heart failure with obesity
This study tests a new medicine called IBI362 for people with heart failure and obesity. The medicine may help improve symptoms and quality of life. You must have a specific type of heart failure (HFpEF or HFmrEF) and a BMI of 28 or higher.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06864026RecruitingPhase 4
Adding tirzepatide to ixekizumab for psoriatic arthritis with weight concerns
This study tests adding tirzepatide (a once-weekly injection for weight and diabetes) to your current treatment with ixekizumab for psoriatic arthritis. It may help with both joint symptoms and weight.
Avondale, ArizonaAges 18 years+ - NCT06868862Recruiting
Exercise and fat loss in young women with overweight or obesity
This study compares two types of exercise (short bursts of intense activity vs. moderate continuous activity) to see which is better for fat loss in young women who have overweight or obesity. The exercises have the same total energy used, so the results can show which type might be more helpful for weight management.
São Paulo, São PauloAges 20–45 - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.