Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06916208Recruiting
Capsinoid supplement study for obese teens
This study tests whether a supplement called capsinoid can help activate brown fat in teenagers with obesity. Brown fat is a type of body fat that burns calories, so this could be a new way to help with weight management.
Palavas-les-FlotsAges 11–18 - NCT07020741Recruiting
Stable isotope study in adults with obesity
This study uses a special test (stable isotopes) to learn about how adults with obesity process food and energy. It may help researchers understand weight and metabolism better.
Urbana, IllinoisAges 19–59 - NCT07254065Recruiting
Preventing obesity early with telehealth support
This study tests a telehealth program to help prevent obesity in pregnant women. It offers support and education through video calls to promote healthy habits.
New Hyde Park, New YorkAges 18 years+ - NCT07529704Recruiting
Early help for healthy weight in young children
This trial tests a program to help families with young children build healthy habits and prevent obesity. It focuses on families facing challenges like low income or housing issues.
Burgos, Castille and LeónAges Any age - NCT07031297Recruiting
Exosome release after a meal in obesity
This study looks at how the body releases tiny particles called exosomes from the upper arm after a meal, specifically in women with obesity. It helps researchers understand how fat tissue responds to eating.
Rochester, MinnesotaAges 18–55 - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT07744022Recruiting
Exercise comparison for children with obesity
This study compares two types of exercise programs — progressive neuromuscular stabilization exercises versus aerobic exercises — to see which one better improves body composition and balance in children with obesity. It aims to find a fun, effective way to help kids move better and feel healthier.
IstanbulAges 12–18 - NCT07566390RecruitingPhase 1
Testing a new weight-loss medicine in healthy adults
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Glendale, CaliforniaAges 18–55 - NCT07231484Recruiting
Grape study for immune and gut health in obesity
This trial tests if eating grapes every day for 4 weeks can improve your immune system and gut health. It is designed for adults with obesity who are willing to keep their diet and activity stable during the study.
Columbia, MissouriAges 18–60 - NCT07559136RecruitingPhase 1
Safety study of HRS9531 injection for teen obesity
This study tests whether a new injectable medication called HRS9531 is safe and well-tolerated in teenagers aged 12–17 with obesity. Researchers will monitor how your body handles the medication and whether it affects your weight.
Wuhan, HubeiAges 12–18 - NCT07693426RecruitingPhase 1
Study of efsubaglutide alfa for obese teenagers
This trial tests an injection called efsubaglutide alfa to help obese teenagers lose weight. It requires following diet and exercise advice for at least 3 months before starting.
Beijing, Beijing MunicipalityAges 12–17 - NCT03514602Recruiting
Help quitting smoking to prevent childhood obesity
This study supports pregnant people who smoke to quit or cut down, using behavior-based coaching. It also measures how changes in smoking may help lower a child’s risk of developing obesity.
Buffalo, New YorkAges 18–39 - NCT07437079RecruitingPhase 1
Testing a new weight-loss medicine in healthy people
This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.
Lenexa, KansasAges 18–55 - NCT06199154RecruitingEarly Phase 1
Inducing labor in women with severe obesity
This study tests starting labor in women with a BMI of 40 or higher. The goal is to learn if certain methods are safe and effective for this group.
Baltimore, MarylandAges 18 years+ - NCT07702890RecruitingPhase 1/Phase 2
Testing a new drug for obesity and type 2 diabetes
This trial tests an investigational drug called GUB-UCN2 in people who are healthy, overweight, or have type 2 diabetes. The goal is to see if the drug is safe and how the body processes it.
NeussAges 18–75 - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07731438Recruiting
Calorie restriction and bone marrow fat in obesity and diabetes
This study tests whether a calorie-restricted diet can change the fat in your bone marrow and how it relates to bone health and energy use. It is for premenopausal women and men who are either obese or lean and do not have diabetes.
PragueAges 21–55 - NCT05219799RecruitingEarly Phase 1
Study breathing and blood vessel responses in adults with obesity
This early study tests how your body’s blood vessels respond when oxygen levels are lower, and whether body weight changes that response. You may be able to join if you’re not pregnant and meet health, blood pressure, and breathing/smoking criteria.
Columbia, MissouriAges 18–45 - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Chandler, ArizonaAges 18–75 - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07693231RecruitingPhase 1
Study of BI 3034701 for healthy or overweight Japanese people
This trial tests different doses of a new medicine in healthy Japanese people and those with obesity or overweight. It aims to see how well the body handles the drug and if it is safe.
Fukuoka, FukuokaAges 18–64 - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Daphne, AlabamaAges 45–99 - NCT07399678RecruitingPhase 1
A study of ALV-100 for overweight people with or without type 2 diabetes
This trial tests a new medication called ALV-100 for safety and how well it works in people who are overweight or have type 2 diabetes. It might help if you have a higher body weight and want to try a new treatment option.
Miami, FloridaAges 18–65 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.