Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT07774065Recruiting
Ventilation strategies in obese patients during laparoscopic surgery
This study tests different ways of using a breathing machine (ventilator) during laparoscopic surgery in people with obesity. The goal is to find a safer and more effective ventilation method for this group.
Galveston, TexasAges 18 years+ - NCT06067906Recruiting
Weight loss diet after pre-eclampsia in overweight women
This trial tests whether a special diet (either a low-calorie or a 'dissociated' diet) helps women who have had pre-eclampsia lose weight. It may help you reduce future health risks.
Le MansAges 18–45 - NCT07757087RecruitingPhase 1
Study on energy use after weight loss
This study tests a new medicine to see how it affects the body's energy use after losing weight. It compares the medicine to a low-calorie diet or a placebo (a pill with no active ingredient) in adults with obesity.
Aarhus NAges 18 years+ - NCT07752979RecruitingPhase 2
New drug for weight loss in adults with obesity or overweight
This study tests an investigational drug called ABBV-295 to see if it helps adults with obesity or overweight who have weight-related health conditions lose weight. It may offer a new treatment option for managing weight and improving overall health.
Pelham, AlabamaAges 18–75 - NCT07754474RecruitingPhase 1
Testing a new medicine for overweight or obesity
This study tests a new drug called BI 3034701 to see how well people tolerate different doses. It may help with weight loss and related health issues.
MannheimAges 18–74 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Birmingham, AlabamaAges 18 years+ - NCT07744022Recruiting
Exercise comparison for children with obesity
This study compares two types of exercise programs — progressive neuromuscular stabilization exercises versus aerobic exercises — to see which one better improves body composition and balance in children with obesity. It aims to find a fun, effective way to help kids move better and feel healthier.
IstanbulAges 12–18 - NCT06616714Recruiting
Weight loss procedure for people with obesity and IBD
This study tests a weight-loss procedure called endoscopic sleeve gastroplasty (a stomach-reducing procedure done through a scope) in people with both obesity and inflammatory bowel disease (IBD). It aims to see if the procedure is safe and helpful for this group.
RomaAges 18–70 - NCT05477212Recruiting
Study gut leakiness in obesity and fatty liver with a ketogenic diet
This study looks at “gut permeability,” sometimes called intestinal leakiness, in people with obesity and fatty liver disease. It tests whether a ketogenic (very low-carb) diet changes gut leakiness and fatty liver measurements.
Castellana Grotte, BARIAges 18–65 - NCT07732426Recruiting
Semaglutide and brain response to food in obesity with food addiction
This trial tests if semaglutide can change how your brain responds to food cues, like seeing or smelling food, in people with obesity and a tendency toward food addiction. It may help understand why some people struggle with overeating and how this medication could help.
SeoulAges 19–50 - NCT07734311RecruitingPhase 3
Testing a weight-loss injection for knee arthritis pain
This study tests whether an experimental weight-loss injection can reduce knee pain in people who are obese and have knee osteoarthritis. It may help if you have been unable to lose weight through diet and exercise and have moderate knee pain.
Wuhan, HubeiAges 18–75 - NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT05974995Recruiting
Robotic or standard surgery for early uterine cancer in obesity
This trial compares robotic-assisted surgery versus standard laparoscopic surgery for people with early-stage uterine (endometrial) cancer and a BMI of 30 or higher. The goal is to see which approach is safer and works better for this group.
RomeAges 18–75 - NCT06626113Recruiting
Nerve activity and obesity study
This trial looks at how the nerves that control blood pressure work in people with obesity and insulin resistance. It may help explain why some people develop high blood pressure and others don't.
Kansas City, KansasAges 18–79 - NCT06395246Recruiting
Weight loss and tiny cell particles study
This study looks at how weight loss from a special diet affects tiny particles in your blood, called microvesicles, that help control your body's energy use. It may help us understand why weight loss improves health for people with obesity.
Tarragona, TarragonaAges 18–70 - NCT07731139RecruitingPhase 1
Testing a new medicine for people with obesity
This study tests how different amounts of the study medicine PF-08642534 are tolerated and how they work in the body of people with obesity. It aims to find a safe dose for future studies.
Lake Forest, CaliforniaAges 18–70 - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07725809RecruitingPhase 1
Study of a new medicine for adults with overweight or obesity
This study tests a new medicine called PF-08653945 to see how it enters the blood in adults who are overweight or have obesity. The results will help doctors understand how the medicine works in the body.
Brussels, Bruxelles-capitale, Région deAges 18 years+ - NCT07731438Recruiting
Calorie restriction and bone marrow fat in obesity and diabetes
This study tests whether a calorie-restricted diet can change the fat in your bone marrow and how it relates to bone health and energy use. It is for premenopausal women and men who are either obese or lean and do not have diabetes.
PragueAges 21–55 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT06642363RecruitingPhase 1
Astaxanthin for PCOS symptoms and heart health
This trial tests if astaxanthin, a natural antioxidant, can improve PCOS symptoms and heart-related health in women with PCOS who are overweight but not pregnant or breastfeeding.
Isfahan, IsfahanAges 18–45 - NCT07702890RecruitingPhase 1/Phase 2
Testing a new drug for obesity and type 2 diabetes
This trial tests an investigational drug called GUB-UCN2 in people who are healthy, overweight, or have type 2 diabetes. The goal is to see if the drug is safe and how the body processes it.
NeussAges 18–75
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.