Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT07496463Enrolling by invitationPhase 2
Setmelanotide for weight loss in pseudohypoparathyroidism type 1a
This study tests an experimental medication called setmelanotide to see if it can help with weight loss in people who have pseudohypoparathyroidism type 1a (PHP1a), a rare genetic condition that often leads to obesity. The goal is to find a new treatment option for weight problems related to PHP1a.
Boston, MassachusettsAges Any age - NCT07284979RecruitingPhase 3
Weekly injection for obesity without diabetes
This trial tests a new once-weekly injection called Ribupatide for weight loss in people with obesity who do not have diabetes. It compares the study drug to an existing medication (semaglutide) and a placebo to see how well it works and if it's safe.
Glendale, ArizonaAges 18 years+ - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Anniston, AlabamaAges 18 years+ - NCT06497595Recruiting
Lifestyle program to prevent muscle loss in older adults with diabetes on semaglutide
This trial tests whether a lifestyle program (diet and exercise) can help prevent muscle loss in people 65 and older with type 2 diabetes and obesity who are taking semaglutide. It may help you keep your strength and independence while losing weight.
Jerusalem, IsraelAges 65 years+ - NCT06745570Recruiting
Sleep, decision-making, and eating habits study for teens with obesity
This study tests whether improving sleep and decision-making skills helps teenagers with obesity make healthier eating choices. It involves both teens and their parents or guardians.
Wilmington, DelawareAges 14–18 - NCT04714892Recruiting
Taste and smell differences in obesity
This study looks at how taste and smell may differ in people with obesity compared to healthy-weight individuals. It aims to understand why some people perceive flavors differently, which could help develop better treatments for weight management.
Bethesda, MarylandAges 18–65 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Tucson, ArizonaAges 6–17 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Ventura, CaliforniaAges 12–17 - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Tuscaloosa, AlabamaAges 18 years+ - NCT07654972RecruitingPhase 1
Study of a new weight loss drug in healthy people with obesity or overweight
This study tests a new medication (LY4174794) for weight loss in people who are overweight or have obesity. It will help see if the drug is safe and how the body processes it.
San Antonio, TexasAges 18–65 - NCT07665879RecruitingPhase 1
Study of an experimental drug for people with overweight or obesity
This trial tests an experimental drug (Eloralintide) to see if it can help with weight management. It is for people who have a body mass index (BMI) between 25 and 45 and stable weight.
NeussAges 18–70 - NCT07284901RecruitingPhase 3
Weekly injection for diabetes and weight loss
This study tests an experimental once-weekly injection called ribupatide for people with type 2 diabetes and overweight. It aims to help them lose weight and better control their blood sugar.
Cullman, AlabamaAges 18 years+ - NCT07667504Recruiting
Dietary approaches for weight management in type 1 diabetes
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Málaga, MálagaAges 18–65 - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65 - NCT03022682Recruiting
Study of inflammation and metabolism across diabetes and weight
This is an observational study that follows generally healthy adults to understand how inflammation, diabetes (type 2), and weight/metabolic health relate to each other. It may help researchers figure out why different groups (including different ethnic backgrounds) have different health risks.
San Francisco, CaliforniaAges 18–75 - NCT03135730Recruiting
ROHHAD patient registry for rapid-onset obesity
This study is a registry that collects information from people diagnosed with, or suspected to have, ROHHAD. It can help researchers better understand the condition over time and improve future care.
Chicago, IllinoisAges Any age - NCT03152617Recruiting
Study on nutrition and mouth health risks after obesity treatment
This trial looks at risks like malnutrition, weak bones, and oral (mouth) health problems after obesity treatment. It may help improve follow-up care for people who receive specialist treatment or weight-loss surgery.
GothenburgAges 18 years+ - NCT03302195Recruiting
Heparin and bypass blood management for obese heart surgery
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Québec, QuebecAges 18 years+ - NCT03402139Recruiting
Study early-life obesity risk after growth restriction
This study looks at how obesity risk may be influenced in children whose growth was lower than expected before birth. It enrolls mothers and babies together to learn whether early childhood obesity programming can help families.
The Bronx, New YorkAges 1 hour–2 years - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03516968RecruitingPhase 3
Monthly vs daily vitamin D for obese children
This study compares taking vitamin D as a monthly dose versus a daily dose in children with low vitamin D levels. It aims to correct the vitamin D deficiency and see which schedule works best and is safe.
BronAges 5–18 - NCT03756961Recruiting
Opioid-free care plan for people having weight-loss surgery
This trial studies whether an opioid-free or opioid-sparing care pathway can improve comfort and outcomes for adults undergoing laparoscopic weight-loss surgery. It may help people avoid side effects from opioid pain medicines while still managing pain safely.
Lindesberg, Region ÖrebroAges 18 years+ - NCT03821636Recruiting
Compare gastric bypass limb lengths for type 2 diabetes remission
This study looks at whether a gastric bypass surgery with a longer intestine segment or a longer bile drainage segment leads to better type 2 diabetes remission in people with severe obesity. It may help doctors choose the most effective surgical approach and follow-up plan for diabetes improvement.
AmiensAges 18–60
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.