Clinical trials
Obsessive-Compulsive Disorder clinical trials
Below are recruiting obsessive-compulsive disorder clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06575075RecruitingPhase 1/Phase 2
Ketamine study for OCD
This study tests a form of ketamine called RR-HNK as a possible new treatment for OCD. It is for people who have not gotten enough relief from standard treatments or chose not to take them.
Palo Alto, CaliforniaAges 18–65 - NCT06582225Recruiting
Online CBT for OCD in children with autism
This study tests if internet-based cognitive behavioral therapy (CBT) can help children and teens with autism who also have OCD. Treatment is delivered online with parent support, making it easier to access care at home.
Lund, Skåne CountyAges 7–17 - NCT06376734RecruitingPhase 2
TMS for depression, anxiety, OCD, or schizophrenia
This study tests whether a brain stimulation technique called TMS can help people with depression, anxiety, OCD, or schizophrenia. It aims to find better ways to target the treatment for each person's specific needs.
Sunnyvale, CaliforniaAges 18–65 - NCT06173752Recruiting
How exposure therapy works for OCD
This study looks at how exposure therapy helps people with OCD. It aims to understand the mechanisms behind why this treatment is effective.
San Diego, CaliforniaAges 18–65 - NCT06102941Recruiting
Cognitive training for OCD in kids aged 8 to 12
This study tests a cognitive training program to help young children with OCD. It's designed for kids whose OCD is their main problem and who are not currently on medication or in other therapy.
New York, New YorkAges 8–12 - NCT02773082Recruiting
Deep brain stimulation for severe OCD
This trial studies whether placing a deep brain stimulation device can reduce symptoms in people with severe obsessive-compulsive disorder (OCD) who did not improve with several standard treatments. It may help when medications and therapy have not worked well enough.
Queens, New YorkAges 18 years+ - NCT04882839RecruitingPhase 2
Therapy with psilocybin for severe OCD symptoms
This Phase 2 study tests whether psilocybin-assisted psychotherapy can reduce symptoms in adults with severe, treatment-resistant OCD. It also focuses on safety and whether this approach is practical to run.
BeershebaAges 18–65 - NCT05940324RecruitingPhase 2
Ketamine study for OCD after prior treatment failed
This Phase 2 study tests how ketamine may work quickly in people with obsessive-compulsive disorder (OCD), especially after at least one standard treatment didn’t help. If you join, you’ll need to follow study procedures like fasting before the experimental visit and not enrolling in other medication trials during the study.
Stanford, CaliforniaAges 18–65 - NCT05931913Recruiting
TMS plus exposure therapy for teenage OCD
This study tests whether combining transcranial magnetic stimulation (TMS) with exposure therapy can help reduce OCD symptoms in young people aged 12-21. TMS is a non-invasive brain stimulation technique. The study aims to see if this combination is more effective than exposure therapy alone.
Minneapolis, MinnesotaAges 12–21 - NCT05783817RecruitingPhase 2
MDMA-assisted therapy for OCD in adults
This trial tests whether MDMA plus cognitive behavioral therapy (CBT) can reduce OCD symptoms in adults who have tried standard OCD treatments before. You may be asked to pause certain medicines and follow specific diet/medication rules around the study session.
Palo Alto, CaliforniaAges 18 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT05659082Enrolling by invitationPhase 3
Brain capsulotomy surgery for severe OCD
This trial is testing whether a specific brain surgery step called a capsulotomy can help people with severe, hard-to-treat obsessive-compulsive disorder (OCD). You would be considered only if your case is approved by the hospital’s psychiatric neurosurgery committee.
Providence, Rhode IslandAges 18–90 - NCT05609916Recruiting
CBT therapy to help kids stop OCD medicine
This trial studies whether adding structured talk therapy (CBT) can help some children with obsessive-compulsive disorder (OCD) reduce and potentially stop their OCD medicine. It’s designed for kids who are still having meaningful symptoms despite being on an OCD medication long enough.
Houston, TexasAges 7–17 - NCT05623306Recruiting
Brain stimulation surgery for OCD using a guided DBS system
This trial studies whether deep brain stimulation surgery—guided using special scans—can reduce severe obsessive-compulsive disorder (OCD) symptoms. It may help people whose OCD has not improved enough with standard medicines and therapy.
Stanford, CaliforniaAges 22–75 - NCT05565352Enrolling by invitation
Ketamine safety study for people in inpatient psychiatric care
This trial looks at whether ketamine is safe and well-tolerated for certain mental health conditions when given in a hospital setting. It may help teams better understand side effects and comfort for people who may be offered ketamine.
GdanskAges 18–90 - NCT05467683Recruiting
Breathing CO2 test to predict which anxiety therapies won’t work
This study uses a controlled breathing test (inhaling CO2 or breathing faster) to see if it can predict whether exposure-based therapy will help your anxiety disorder. If you are in the right group, the results may help doctors choose more effective treatment earlier.
Boston, MassachusettsAges 18–70 - NCT05377125Recruiting
Training brain skills to reduce urges in OCD spectrum
This study tests a training program meant to improve “response inhibition,” the brain’s ability to pause before acting on unwanted urges. It may help people with OCD-spectrum conditions like obsessive-compulsive disorder, trichotillomania (hair pulling), or skin picking by targeting brain control of impulses.
Milwaukee, WisconsinAges 18–60 - NCT05224414Recruiting
Study of how thinking styles may affect OCD treatment response
This study looks at how your interpretation of unclear situations may influence how well OCD treatment works. You’ll likely complete a computer task to understand thinking patterns and response to the main OCD study protocol.
Belmont, MassachusettsAges 18 years+ - NCT05254015Enrolling by invitation
Therapy for hoarding symptoms in adults 50+
This trial tests a combined therapy approach (cognitive rehabilitation plus exposure therapy) to reduce hoarding behaviors in older adults. You may benefit if your hoarding is your main diagnosis and your symptoms and medications are stable.
San Diego, CaliforniaAges 50 years+ - NCT05160129Recruiting
Deep brain stimulation for severe OCD using targeted electrodes
This study tests a deep brain stimulation (DBS) treatment device for adults with severe, long-lasting obsessive-compulsive disorder (OCD) that has not improved with standard treatments. It may help reduce OCD symptoms and improve daily functioning when medications and therapy have not worked.
New York, New YorkAges 18 years+ - NCT04934007Recruiting
Brain stimulation for OCD after medicines didn’t work
This trial studies a non-surgical brain stimulation treatment (rTMS) delivered to both sides of the brain for people with obsessive-compulsive disorder (OCD). It may help those whose OCD has not improved after trying at least two different OCD medicines.
ParisAges 18–65 - NCT04899687RecruitingPhase 2
Dextromethorphan for OCD and related anxiety conditions
This trial studies dextromethorphan, a medicine sometimes used for cough, to see if it can reduce symptoms in OCD and similar conditions. It may help people whose intrusive thoughts or related worries are still challenging despite current care.
Stanford, CaliforniaAges 18–65 - NCT04480918Recruiting
Registry for people with depression or bipolar to receive psychiatry care
This is a patient registry that enrolls people being evaluated for treatment options from an Interventional Psychiatry Service. It helps track patients with depression, bipolar disorder, or treatment-resistant OCD who are suitable for these psychiatry treatments.
Iowa City, IowaAges 18–99
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Common questions
- Are there clinical trials for obsessive-compulsive disorder?
- Yes. Clin2 currently lists 104 recruiting obsessive-compulsive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obsessive-compulsive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obsessive-compulsive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.