Clinical trials
Sleep Apnea Syndrome, Obstructive clinical trials
Below are recruiting sleep apnea syndrome, obstructive clinical trials, each written for real people, not researchers. We’re tracking 116 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07226765RecruitingPhase 3
Weight-loss drug for sleep apnea without CPAP
This study tests a new weight-loss medication called maridebart cafraglutide against a placebo in people with moderate to severe obstructive sleep apnea who are not using a CPAP machine. The goal is to find out if weight loss can reduce symptoms like pauses in breathing during sleep.
Northridge, CaliforniaAges 18–99 - NCT06447818Recruiting
Airway changes after sleep apnea surgery
This study looks at how surgery for obstructive sleep apnea (a condition where breathing stops and starts during sleep) may affect your airway. The goal is to understand if the surgery makes it easier to manage your airway in the future.
Kocaeli, IzmıtAges 18–65 - NCT06283095Recruiting
Expanding the palate to help sleep apnea
This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.
AsyutAges 18–70 - NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Northridge, CaliforniaAges 18–99 - NCT07730879Recruiting
Wall Squat Exercise for Blood Pressure in Sleep Apnea
This study tests whether a simple wall squat exercise can help lower blood pressure in people who have both high blood pressure and sleep apnea (treated with CPAP). If you are using CPAP regularly and are otherwise healthy enough to exercise, this trial may be a good fit for you.
BragaAges 18–80 - NCT07555119Recruiting
Home Sleep Testing: Night-to-Night Measurement Variability Study
This study measures how sleep breathing patterns vary from night to night using home sleep testing. It helps researchers understand if portable sleep tests give consistent and reliable results.
BernAges 18 years+ - NCT07635563RecruitingPhase 2
Sleep Apnea Treatment with Dronabinol and Acetazolamide
This study tests a combination medication (dronabinol and acetazolamide) to treat obstructive sleep apnea in people who cannot tolerate or use CPAP machines. The goal is to find the right dose that safely reduces breathing interruptions during sleep.
Chula Vista, CaliforniaAges 18–65 - NCT06576310Recruiting
Predicting teeth changes from sleep apnea mouthpiece treatment
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
ToulouseAges 18 years+ - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04399200Recruiting
Study apnea after stroke to prevent new heart events
This trial looks at sleep apnea (breathing pauses during sleep) in people soon after a first stroke or a TIA, to see if it can be linked to new cardiovascular (heart/blood vessel) events. It also aims to make sure you can safely follow the study and rehabilitation plan.
GrenobleAges 18–85 - NCT04572503Recruiting
Surgery for mild to moderate sleep apnea not helped by CPAP
This trial looks at a modified palate surgery to treat mild to moderate obstructive sleep apnea in people whose CPAP machine isn’t working for them. It may help if your sleep apnea is caused by the tissue behind the soft palate collapsing rather than other airway areas.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT04659291Recruiting
Studying people in Hong Kong who may have sleep apnea
This study looks at people who may have obstructive sleep apnea, a breathing problem during sleep. It aims to better understand the condition in Hong Kong and what to do next for diagnosis or care.
Hong Kong, Please SelectAges 18 years+ - NCT04943562Recruiting
Testing sleep sensors to score your sleep stages
This study checks whether wearable sensors (like a sleep band and a wearable EEG) and a phone can accurately identify your sleep stages. It includes healthy people and people with sleep problems to see how well the devices work and whether results match a standard sleep lab test.
São Caetano do Sul, São PauloAges 20–80 - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05382754Recruiting
Home sleep testing for children being checked for sleep apnea
This trial tests whether home sleep testing can help diagnose sleep apnea in children. It is for kids who are already being referred for an in-lab sleep study at CHOP.
Philadelphia, PennsylvaniaAges 5–12 - NCT05497180RecruitingPhase 1
Testing an oral device to reduce snoring and mild sleep apnea
This Phase 1 study tests whether a passive mouth/oral appliance can lessen snoring and mild obstructive sleep apnea. It may help you by improving airflow during sleep without other intensive treatments.
Edmonton, AlbertaAges 18 years+ - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for sleep apnea syndrome, obstructive?
- Yes. Clin2 currently lists 116 recruiting sleep apnea syndrome, obstructive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sleep apnea syndrome, obstructive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sleep apnea syndrome, obstructive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.