Clinical trials
Older Adults clinical trials
Below are recruiting older adults clinical trials, each written for real people, not researchers. We’re tracking 526 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06837857RecruitingPhase 2
Opioid pain relief study for older adults with chronic pain
This study tests whether a carefully managed prescription opioid can safely help older adults with long-term pain that hasn't been relieved by other pain medicines. The goal is to see if it improves pain without harming memory or brain health.
Rochester, MinnesotaAges 65 years+ - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100 - NCT06819254RecruitingPhase 4
Fisetin for fatigue in older cancer survivors
This study tests whether a natural compound called fisetin can reduce fatigue in people aged 60+ who have completed cancer treatment. If you still feel tired often, this pill-based treatment might help you regain energy.
Winston-Salem, North CarolinaAges 65 years+ - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06812143Recruiting
Strength Training Study for Adults 65 and Older
This study tests a strength training program designed for older adults who are not currently active. The goal is to find the best way to improve strength and overall health in people over 65.
Flushing, New YorkAges 65 years+ - NCT06799936Recruiting
Helping older adults with kidney disease make treatment choices
This study tests a program that helps older adults with advanced chronic kidney disease talk with their doctors about treatment options, like dialysis, palliative care, or a kidney transplant. It aims to make sure patients' values and preferences are heard in these important decisions.
Hong KongAges 65 years+ - NCT06802289Recruiting
Preventing frailty by keeping seniors active in the hospital
This trial tests whether a mobility program helps older adults stay strong and avoid frailty during a hospital stay. If you are 50 or older and expect to be in the hospital for at least 3 days, this study may offer extra support to keep you moving.
Moncton, New BrunswickAges 50 years+ - NCT06634147Recruiting
Exercise program to prevent decline in hospitalized older adults
This study is testing a gentle exercise program for older adults (75+) while they are in the hospital. The goal is to see if it helps prevent loss of strength, memory, or thinking skills.
Pamplona, NavarreAges 75 years+ - NCT06779188RecruitingEarly Phase 1
Brain stimulation to improve balance in older adults
This trial tests whether a non-invasive brain stimulation technique called theta burst TMS can improve balance and brain connectivity in adults over 65 who have had recent falls. It involves MRI scans, 4 weeks of treatment, and follow-up tests.
Houston, TexasAges 65 years+ - NCT06774833Recruiting
Fall prevention training for older adults
This study tests a training program that helps you react to unexpected trips or slips to prevent falls. It is for older adults who are worried about falling or have fallen before.
Hong KongAges 60 years+ - NCT06777693Enrolling by invitation
Unified Protocol for emotional disorders in older adults
This study tests a group therapy program for older adults with anxiety or depression. The program teaches skills to manage difficult emotions and improve emotional well-being.
Bergen, VestlandAges 65 years+ - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06781749Recruiting
Measuring social engagement in older adults with hearing loss
This study tests a new way to objectively measure how socially engaged older adults with hearing loss are. It may help researchers better understand the impact of hearing loss on social participation.
Los Angeles, CaliforniaAges 60 years+ - NCT06771531Recruiting
Brain stimulation for foot sensation in older adults
This trial tests whether a gentle brain stimulation technique can improve feeling and steadiness in the feet of older adults who have numbness or reduced sensation. It aims to help with balance and walking.
Roslindale, MassachusettsAges 65 years+ - NCT06701188Recruiting
Virtual support program for older adults after cardiac rehab
This study tests a virtual support program to help older adults stay active and healthy after completing cardiac rehabilitation. It may help you maintain the benefits of rehab and improve your heart health.
San Francisco, CaliforniaAges 55–100 - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT06733636Recruiting
Smell training for older adults with smell loss
This study tests whether a special device can help older adults regain their sense of smell through regular training with different scents. It is designed for people who have lost smell due to aging or other causes, not from birth.
Baltimore, MarylandAges 60 years+ - NCT06731413RecruitingPhase 2
Mild chemo with immunotherapy for older adults with advanced lung cancer
This study tests a milder chemotherapy combined with an immunotherapy drug (anti-PD-1) as the first treatment for advanced lung cancer in older or frailer adults. It aims to see if this approach works better with fewer side effects.
Richmond, VirginiaAges 18 years+ - NCT06727305RecruitingPhase 1/Phase 2
Sirolimus Study for Healthy Aging in Older Adults
This study tests a medication called sirolimus to see if it can help older adults stay healthy and independent. The trial is looking for people aged 65 and older who live at home and do not have serious memory problems or major health conditions like kidney or liver disease.
Dallas, TexasAges 65–80 - NCT06721559Recruiting
Home program for older adults with depression and mobility issues
This study tests a home-based program called Empower@Home for older adults who have depression and trouble moving around. It aims to see if the program helps improve mood and daily life—without adding extra outside therapy.
Ann Arbor, MichiganAges 50 years+ - NCT06706479Enrolling by invitation
Brain stimulation for balance in older adults with back pain
This study tests whether a gentle, non-invasive electrical brain stimulation technique (called high-definition tDCS) can improve balance in older adults with chronic low back pain. Participants receive either real or sham stimulation during balance training sessions.
Hong Kong, Hong KongAges 60–85 - NCT06697600Recruiting
Supporting decisions for older adults with AML and their caregivers
This study helps older adults with newly diagnosed acute myeloid leukemia (AML) and their caregivers make informed decisions about treatment. You and a caregiver (like a family member or friend) will get extra support to talk through your options.
Birmingham, AlabamaAges 60 years+
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Common questions
- Are there clinical trials for older adults?
- Yes. Clin2 currently lists 526 recruiting older adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a older adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a older adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.