Clinical trials
Opioid Use Disorder clinical trials
Below are recruiting opioid use disorder clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07135323Recruiting
AvertD Test for First-Time Opioid Users
This study is testing a new tool called AvertD that helps doctors see if a patient might be at higher risk of developing opioid use disorder before they get their first opioid painkiller prescription. If you are getting your first opioid prescription for 4 to 30 days, you may be able to join.
Indianapolis, IndianaAges 18 years+ - NCT07169409RecruitingPhase 1
Telehealth for opioid use disorder in vulnerable settings
This trial tests whether a telehealth program can help people with opioid use disorder get and stay on buprenorphine treatment. It aims to make care more accessible for those in vulnerable situations.
Portland, OregonAges 18 years+ - NCT07171359Recruiting
TMS therapy for opioid and alcohol use recovery
This trial tests whether TMS (a non-invasive brain stimulation) can improve recovery for people with both opioid and alcohol use disorders. You must be in a specific outpatient program in Portland, Oregon.
Portland, OregonAges 18 years+ - NCT07178990Recruiting
Wellness and recovery app for people on opioid treatment
This study tests if a smartphone app can help people taking medications for opioid use disorder and who also have alcohol use disorder. You will use the app for 6 months and provide feedback through surveys and saliva drug tests.
Ann Arbor, MichiganAges 19–63 - NCT07197801Recruiting
Peer support program for opioid use disorder treatment
This study tests if a peer recovery support program helps people stay in treatment for opioid use disorder. Participants who recently started medication for opioid use disorder may get extra support from a peer who has been through recovery themselves.
Danville, PennsylvaniaAges 18–89 - NCT07214467Recruiting
Adaptive brain stimulation for opioid use disorder
This study tests a new type of brain stimulation that adapts to your brain activity, aiming to reduce cravings and help you control opioid use. It is for people with long-standing opioid use disorder who have not gotten lasting relief from at least 3 treatment attempts, including medication.
San Francisco, CaliforniaAges 22–75 - NCT07226570Recruiting
Ibogaine brain mapping study for opioid use disorder
This study uses MRI and EEG scans to map how ibogaine affects the brain in people with opioid use disorder. You must already be scheduled to receive ibogaine treatment in Tijuana, Mexico, on your own, as the study does not cover treatment costs.
Irvine, CaliforniaAges 21–70 - NCT07232641Recruiting
How pandemic rules affected opioid addiction treatment in the VA
This study looks at how changes in federal and state rules about medications for opioid use disorder during the pandemic affected veterans. It uses information already in your VA records, so there are no extra visits or tests needed.
Boston, MassachusettsAges 18 years+ - NCT07278518Recruiting
Emergency department decision aid for buprenorphine
This trial is testing a tool to help people in the emergency department decide whether to start buprenorphine (a medication for opioid use disorder). It's for patients who are not already on medication for their condition.
Charleston, South CarolinaAges 18 years+ - NCT07342504Recruiting
Brief alcohol support for people on buprenorphine
This trial tests a brief alcohol-focused support program designed for people who are already taking buprenorphine for opioid addiction. The goal is to help you reduce your drinking in a way that fits with your current treatment.
Notre Dame, IndianaAges 18 years+ - NCT07179614Recruiting
Kentucky women's overdose recovery program
This trial tests a support program for women in Kentucky jails who have opioid or stimulant use disorder. It aims to reduce overdose risk after release by connecting them with community support.
Harlan, KentuckyAges 18 years+ - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT07158853RecruitingPhase 1
Brain stimulation and training for opioid use disorder
This trial combines a gentle brain stimulation technique called tDCS with thinking exercises to see if it helps people with opioid use disorder who are already on medication. It aims to improve treatment outcomes
Minneapolis, MinnesotaAges 18 years+ - NCT07466784Recruiting
Opioid use registry for emergency patients
This study is for people who come to the emergency department because of an opioid overdose, withdrawal, or related problem. It will collect information about patients' experiences to help improve care and support for opioid use.
Vancouver, British ColumbiaAges Any age - NCT06432465Recruiting
Brain stimulation to help prevent opioid relapse
This study uses a type of brain stimulation called tDCS (transcranial direct current stimulation) to see if it can help people who have recently started medication for opioid dependence (buprenorphine or methadone) stay on track and avoid relapse. The treatment is non-invasive and involves a mild electrical current applied to the scalp.
Providence, Rhode IslandAges 21–60 - NCT07558187Recruiting
Health Inequalities Study in Rural and Urban Communities
This research study examines how health differences vary between rural and urban areas and among different groups of people. Researchers want to understand what factors affect health outcomes and why some communities experience worse health than others.
LarissaAges 18 years+ - NCT07632053Recruiting
Support Program for Mothers With Opioid Addiction
This study offers support and treatment for mothers struggling with opioid use disorder who have a child age 5 or younger. Researchers will provide intervention and assess brain imaging to understand how best to help mothers and their families.
Ann Arbor, MichiganAges 18–50 - NCT07620171Enrolling by invitation
Peer Support to Help You Stay in Opioid Treatment
This study tests whether talking regularly with someone who has recovered from opioid addiction helps you stay in buprenorphine treatment longer. Buprenorphine is a medication that reduces cravings and withdrawal, and peer support may help you stick with it.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07490717Enrolling by invitation
Treating PTSD and opioid use in jails
This study tests new ways to screen and treat people in jail who have both post-traumatic stress disorder (PTSD) and opioid use disorder. It aims to help participants with therapy while incarcerated and after release.
Little Rock, ArkansasAges 18 years+ - NCT06965010Enrolling by invitation
Tracking Care in Opioid Treatment Programs
This study tests whether tracking your progress with regular check-ins (measurement-based care) helps improve treatment for people starting medication for opioid use disorder at a treatment program.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06956352Enrolling by invitation
Study on better care for pregnant women with opioid use disorder
This study tests a team-based approach to help pregnant women with opioid use disorder get better support during pregnancy. It may improve care for mothers and babies.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06857968Enrolling by invitation
Mobile mindfulness training for opioid use disorder treatment
This study tests if a mobile mindfulness training app can help people who are receiving medication treatment for opioid use disorder. It is for people with a history of childhood trauma who are stable on their medication.
Lexington, KentuckyAges 18–65 - NCT06477848Enrolling by invitation
Improving care for teens with opioid use disorder in pediatric clinics
This study looks at how to better support teens with opioid use disorder in pediatric primary care. It involves training clinic staff and gathering feedback from both providers and patients.
Indianapolis, IndianaAges 12 years+ - NCT05336188Enrolling by invitation
Smartphone help to prevent relapse in opioid use disorder
This study looks at whether a smartphone-based program can help people avoid relapse from opioid use disorder. Some participants may also do brain scans to better understand the brain changes behind relapse prevention.
Little Rock, ArkansasAges 18 years+
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Common questions
- Are there clinical trials for opioid use disorder?
- Yes. Clin2 currently lists 296 recruiting opioid use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a opioid use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a opioid use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.