Clinical trials
Oral Disease clinical trials
Below are recruiting oral disease clinical trials, each written for real people, not researchers. We’re tracking 192 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03337932Recruiting
Shorter doxycycline course for multiple early Lyme skin rashes
This study looks at how long to take doxycycline for people who have multiple early Lyme disease skin rashes. It may help find the shortest effective treatment duration while keeping side effects low.
LjubljanaAges 18 years+ - NCT06252493Recruiting
PET/MR scan for Crohn's disease scar tissue
This study is testing a new imaging method that uses a special PET/MR scan to see how active Crohn's disease is in your bowel. The scan uses a harmless radioactive tracer that attaches to scar tissue, which may help doctors better understand the disease and guide treatment.
Charlestown, MassachusettsAges 18–99 - NCT03781700RecruitingPhase 4
Cortisone treatment for sudden facial weakness in children
This trial tests whether cortisone (prednisolone) helps children recover from a sudden one-sided facial nerve problem. It mainly compares active medicine vs placebo, with follow-up planned for about 12 months.
Falun, Dalarna CountyAges 1–17 - NCT05587049Recruiting
Testing an oral medicine plus azacitidine to improve AML disease
This study looks at how a standard AML treatment plan affects a person’s disease status over time. It focuses on newly diagnosed adults who cannot safely get intensive chemotherapy, using oral venetoclax plus azacitidine.
Medellín, AntioquiaAges 18 years+ - NCT06664125RecruitingPhase 2
New drug for high phosphorus in dialysis patients
This trial tests a new drug, JMKX003002, to lower high phosphorus levels in people with end-stage kidney disease who are on hemodialysis. If you have trouble controlling your phosphorus, this treatment might help.
Guangzhou, GuangdongAges 18 years+ - NCT04246437RecruitingPhase 1
Brain imaging study for autonomic failure with possible Parkinson disease
This Phase 1 study uses a special injected imaging tracer and an MRI scan to look at brain function in people with autonomic failure. It may help researchers understand what’s happening in conditions that can be related to Parkinson disease, multiple system atrophy, or dementia with Lewy bodies.
Nashville, TennesseeAges 18 years+ - NCT07015996RecruitingPhase 2
Tezepelumab for peanut allergy oral immunotherapy
This trial tests whether adding tezepelumab (a biologic drug) to peanut oral immunotherapy can help people with peanut allergy better tolerate small amounts of peanut protein without having an allergic reaction.
Little Rock, ArkansasAges 12–55 - NCT07636733Recruiting
Vitamin D for Gum and Bone Health in Periodontal Disease
This study tests whether vitamin D supplements can reduce inflammation and improve healing in people with gum disease, ranging from mild gingivitis to advanced periodontitis. Researchers will compare how vitamin D affects different stages of gum disease.
RizeAges 18–70 - NCT06555029Recruiting
Oral health help for older adults on Medicaid
This trial is testing an oral health program offered during routine primary care visits for older adults (55+) on Medicaid. It aims to see if adding dental care support to regular check-ups can improve health.
Cleveland, OhioAges 55 years+ - NCT07581002RecruitingPhase 2/Phase 3
New AML Treatment With Three Drug Combination Study
This study tests a new three-drug combination (pivekimab sunirine, venetoclax, and azacitidine) for newly diagnosed acute myeloid leukemia in patients who cannot tolerate intensive chemotherapy. The goal is to see if this combination is safe and effective at controlling the disease.
Duarte, CaliforniaAges 18 years+ - NCT06847139Recruiting
Zinc vs. folic acid for high homocysteine in kidney dialysis
This trial tests whether zinc supplements can lower high homocysteine levels better than folic acid in people with chronic kidney disease who are on hemodialysis. It aims to find a simple, safe way to help protect your heart and blood vessels.
ChittagongAges Any age - NCT04856488RecruitingPhase 3
Lugol’s iodine solution before thyroid surgery for overactive thyroid
This trial tests whether taking Lugol’s iodine solution before thyroid surgery is safe and helpful for people with Graves’ disease or toxic nodular goiter (overactive thyroid). It may be aimed at improving surgical readiness and outcomes by reducing thyroid activity before the operation.
Solna, Stockholm CountyAges 18–75 - NCT07183462RecruitingPhase 4
Antibiotic treatment for late preterm water breaking
This trial tests whether a combination of two antibiotics (azithromycin and ampicillin) can help pregnant people whose water has broken between 34 and 36 weeks of pregnancy. The goal is to see if this treatment improves outcomes for both the parent and baby without causing early labor or infection.
Ramat Gan, IsraelAges 18–50 - NCT07559396RecruitingPhase 1
Safety study of INCB123667 in adults with severe kidney disease
This study tests how a new experimental drug (INCB123667) works and is tolerated in adults with severe kidney problems or end-stage kidney disease. Researchers want to understand how the drug moves through the body and whether it's safe for people in your situation.
Miami Lakes, FloridaAges 18–85 - NCT06781619Recruiting
Plant-based drink study for people at risk of malnutrition
This study tests a plant-based, high-energy, high-protein drink for people who are at medium or high risk of malnutrition. You would replace your current prescribed supplement with either a plant-based or dairy-based drink for 8 weeks to see how it affects your nutrition.
MechelenAges 18 years+ - NCT01805869Recruiting
Teeth removal study using leftover tissue for research
This study looks at people who need wisdom tooth (third molar) removal and collects the leftover tissue after extraction. The goal is to use these samples to help dental research, while making sure the procedure can be done safely.
Bethesda, MarylandAges 16–50 - NCT06942312Enrolling by invitation
Liver metabolism study in non-alcoholic fatty liver disease
This trial studies how the liver processes fat in people with non-alcoholic fatty liver disease (NAFLD). It uses MRI scans to look at liver metabolism, which may help doctors understand the disease better and find new treatments.
Helsinki, UusimaaAges 18–75 - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06158620RecruitingPhase 1/Phase 2
Nasal spray for pain after ureter stent placement
This trial tests whether a nasal spray form of the painkiller ketorolac can safely reduce pain from a ureteral stent after stone surgery. If you are having a ureteroscopy with stent placement, this might help you manage discomfort without stronger medications.
Dallas, TexasAges 18 years+ - NCT07559474RecruitingPhase 1
Safety Study of INCB123667 in Adults With Liver Damage
This study tests how a new experimental medicine (INCB123667) works and is tolerated in adults with moderate to severe liver problems. Researchers want to understand how the body processes this drug and whether it's safe in people with liver dysfunction.
Chandler, ArizonaAges 18–80 - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT06743464Recruiting
Rifaximin before liver transplant for better early liver function
This trial tests whether taking the antibiotic rifaximin just before and after a living-donor liver transplant can help prevent early problems with the new liver. It may be an option for adults having this surgery at the study hospital.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80
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Common questions
- Are there clinical trials for oral disease?
- Yes. Clin2 currently lists 192 recruiting oral disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.