Clinical trials
Oral Infection clinical trials
Below are recruiting oral infection clinical trials, each written for real people, not researchers. We’re tracking 74 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05603650Recruiting
Mouthwash study for healthy bacteria in your mouth and gut
This study tests how a mouthrinse changes the helpful bacteria in your mouth and stomach/gut. You may need several visits and phone follow-ups to see how your microbiome shifts over time.
Irvine, CaliforniaAges 18 years+ - NCT06890676Recruiting
Dental care in nursing homes to prevent infections and improve health
This study tests whether bringing dental care to nursing home residents can reduce mouth infections, pneumonia, and help control blood sugar in people with diabetes. If you live in a nursing home and are 60 or older, you may be able to join.
Jefferson City, MissouriAges 60–100 - NCT06827496Recruiting
Starting with oral antibiotics for kids' bone and joint infections
This study tests if starting treatment for uncomplicated bone or joint infections in children with oral (by mouth) antibiotics is effective. It focuses on kids who are not severely ill and do not have certain risk factors, and who can begin oral antibiotics right away or after a short course of IV (intravenous) antibiotics.
Copenhagen ØAges 3 months–17 years - NCT06715306Recruiting
IV vs. Oral Antibiotics for Common Infections
This trial compares starting antibiotics through a vein (IV) to taking them by mouth for common infections like pneumonia, urinary tract infections, or skin infections (cellulitis). The goal is to see if oral antibiotics work just as well without the need for an IV line.
Aabenraa, Southern DenmarkAges 18 years+ - NCT05553652Recruiting
A probiotic test for repeat bladder infections
This trial studies ASTARTE™, a probiotic, to see if it can reduce repeat urinary tract infections (UTIs). It may help people who get UTIs often by testing whether the supplement lowers how frequently they come back.
Hvidovre, CopenhagenAges 18–40 - NCT05721781Recruiting
Reducing infection risk after gum and tooth issues
This study looks at ways to lower the risk of infective endocarditis, a serious heart infection that can happen after certain bacteria enter the bloodstream from the mouth. You may be asked to pause routine dental cleanings for a period while they track dental health and infection risk.
Boston, MassachusettsAges 18 years+ - NCT06055868Recruiting
HIV, oral cancer, and health equity study
This study looks at the experiences of people living with HIV who also have oral or throat cancer. The goal is to understand health disparities and improve care.
San Francisco, CaliforniaAges 18 years+ - NCT05819229Recruiting
Antibiotics by mouth only for young babies with urine infection
This trial studies whether giving antibiotics by mouth alone is enough to treat a urinary tract infection (UTI) in very young babies. It may help reduce the need for stronger or more invasive antibiotic approaches if you meet the study’s stability and urine-test requirements.
CopenhagenAges 4 weeks–2 months - NCT04538053RecruitingPhase 4
Simpler antibiotics for uncomplicated bone and joint infections in children
This trial looks at whether a simpler antibiotic plan can work for children with uncomplicated bone or joint infections that start in the community. It may help reduce the need for complicated treatment while still keeping the infection under control.
Kingswood, New South WalesAges 1–18 - NCT07552038Recruiting
Dental Care Management for People Living With HIV
This study looks at how dentists can best care for people with HIV. Researchers will review dental and health records at hospitals in the Pays de la Loire region to understand what works best for keeping teeth and gums healthy when you have HIV.
Nantes, NantesAges 18 years+ - NCT05266807RecruitingPhase 3
Capsule fecal transplant to prevent C. difficile coming back
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
Basel, BaselAges 18 years+ - NCT05266898RecruitingPhase 4
HPV vaccine response study for people living with HIV
This trial studies how well the Gardasil-9 HPV vaccine triggers the body’s immune response in people living with HIV. It may help doctors understand the best way to protect against HPV-related cancers and infections in this population.
New Orleans, LouisianaAges 18–65 - NCT06607887RecruitingPhase 4
Antibiotics after gallbladder surgery
This trial tests whether taking antibiotics after laparoscopic gallbladder removal helps prevent infection. It aims to find out if antibiotics are needed for patients without certain health conditions.
MinyaAges 18 years+ - NCT06080698Recruiting
Oral antibiotics for bloodstream infection trial
This trial tests whether switching from IV to oral antibiotics is just as effective for treating Gram-negative bloodstream infections. If you qualify, you may receive either continued IV antibiotics or switch to pills, with follow-up on your recovery and quality of life.
San Francisco, CaliforniaAges 18 years+ - NCT05911750Recruiting
HPV study in men with Crohn’s or ulcerative colitis
This study looks at how common human papillomavirus (HPV) is in men with Crohn’s disease or ulcerative colitis and what it may mean for health. You would answer questions and provide biology samples so researchers can understand the link, if any, between HPV and bowel disease.
BarcelonaAges 18–79 - NCT06310551RecruitingPhase 1
Long-acting HIV prevention study for healthy adults
This study tests a new long-acting medicine that may help prevent HIV. It is given as an injection, and the study checks how safe it is and how it works in healthy volunteers.
Lenexa, KansasAges 18–55 - NCT06749054RecruitingPhase 2
Long-acting HIV treatment for teens and children with drug resistance
This trial tests a long-acting injection called lenacapavir for children and teens with HIV who have tried other treatments and still have detectable virus. It may be an option if current medicines aren't working well enough.
Atlanta, GeorgiaAges Up to 17 years - NCT07727642Recruiting
Optimizing HIV Medicines for AIDS-Related Lymphoma
This trial helps doctors find the best way to combine HIV medicines (antiretroviral therapy) with lymphoma treatment for people who have both HIV and AIDS-related lymphoma. The goal is to improve your overall care and outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05761197Recruiting
Study of mouth yeast infection and a preventive treatment
This trial studies children ages 9–15 months and looks at oropharyngeal yeast infection in the mouth (often called “OPC”). It may help researchers understand how to prevent or manage this condition.
Philadelphia, PennsylvaniaAges 9 months–1.3 years - NCT07275606RecruitingPhase 1/Phase 2
Testing HIV prevention medicine cabotegravir in newborns
This study tests a long-acting injectable HIV prevention medicine called cabotegravir in newborn babies who were exposed to HIV. The goal is to see if it can help protect them from getting HIV.
Parow ValleyAges Up to 1 week - NCT07584122Recruiting
Increasing HIV Prevention Access in Rio de Janeiro
This study helps people at higher risk of HIV get access to PrEP, a daily medication that prevents HIV infection. The program focuses on underserved communities in Rio de Janeiro and aims to make PrEP easier to access and use.
Nova Iguaçu, Rio de JaneiroAges 15 years+ - NCT05398679RecruitingPhase 4
Oral antibiotics versus IV antibiotics after heart infection
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
Alicante, AlicanteAges 18 years+ - NCT05706116RecruitingPhase 1
Study gives worm eggs by mouth to healthy adults
This Phase 1 trial tests how safe and tolerated orally taken Trichuris trichiura (a type of intestinal worm) eggs are in healthy adults. It aims to help researchers understand early safety and study setup before any future treatments.
Washington D.C., District of ColumbiaAges 18–45 - NCT05157685RecruitingPhase 3
Azithromycin for chronic pus-filled sinus inflammation
This Phase 3 trial tests whether the antibiotic azithromycin can improve chronic sinus problems where there is persistent pus and swelling. It’s for adults who have not improved despite at least two prior antibiotics.
BordeauxAges 18–70
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Common questions
- Are there clinical trials for oral infection?
- Yes. Clin2 currently lists 74 recruiting oral infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.