Clinical trials
Orthopedics clinical trials
Below are recruiting orthopedics clinical trials, each written for real people, not researchers. We’re tracking 121 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06179004RecruitingPhase 3
Numbing medicine comparison for wrist surgery pain
This study compares two types of numbing medicine (bupivacaine and liposomal bupivacaine) given near the collarbone before wrist surgery to see which provides better pain relief afterward.
Chapel Hill, North CarolinaAges 18 years+ - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT06341920Recruiting
BoneFit: exercise before hip or knee replacement
This trial tests a pre-surgery exercise program called BoneFit for people waiting at least 6 months for a hip or knee replacement. The goal is to see if getting stronger before surgery helps recovery.
HullAges 18–75 - NCT06365710Recruiting
Physiotherapy vs telerehab after wrist fracture surgery
This study compares in-person physiotherapy with remote telerehabilitation after a specific type of wrist fracture surgery. It aims to see if doing rehab at home works as well as going to a clinic.
Helsinki, UusimaaAges 18–65 - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06406647Recruiting
Nerve block for arm surgery
This trial tests a nerve block to help with pain during and after upper arm surgery. The goal is to see if it works well and is safe for patients.
AsyutAges 20–65 - NCT06459986Recruiting
How long does spinal anesthesia last? A study in orthopedic surgery
This study tracks how long spinal anesthesia lasts during planned orthopedic surgeries. By collecting real-world data, doctors hope to improve timing and care for patients having this type of anesthesia.
HillerødAges 18–100 - NCT06467409RecruitingPhase 2
Study of LPM3480392 for pain after knee surgery
This trial tests an injection called LPM3480392 to see if it safely reduces moderate to severe pain after knee replacement or ligament repair surgery. It aims to help people who need strong pain relief after this type of surgery.
WuhanAges 18 years+ - NCT06471075Recruiting
Mindfulness for Pain Before Orthopedic Procedure
This study tests whether a short mindfulness (calm focus) exercise before an in-clinic orthopedic procedure can help reduce pain. If you are getting kyphoplasty or radiofrequency ablation at Tallahassee Orthopedic Center, this brief program might make your experience more comfortable.
Tallahassee, FloridaAges 18 years+ - NCT07432009Recruiting
Hip replacement and confusion risk in older adults
This study looks at whether older adults who get a hip replacement may experience confusion after surgery. It aims to find factors that might help prevent or reduce this confusion.
BrnoAges 65 years+ - NCT06579599Recruiting
Preventing surgical issues with a doctor-nurse team
This study tests whether a new team approach—where doctors and nurses work closely together in the operating room—can help prevent problems during orthopedic surgery. If you are having surgery for a bone or joint issue at this hospital, you may be able to join.
Yiwu, ZhejiangAges 18–70 - NCT06624969Recruiting
Virtual reality for reducing orthopedic pain
This trial tests if using a virtual reality headset can help reduce pain for people in the hospital with a broken bone. You would use the headset while resting or during procedures to see if it eases discomfort.
Jacksonville, FloridaAges 18 years+ - NCT06627673Recruiting
A new knee implant study for severe arthritis
This study compares a new plastic-and-metal knee implant to a standard metal one for people with severe knee arthritis. If you need a total knee replacement and your knee is not too bent or twisted, you may be a candidate.
Leawood, KansasAges 18 years+ - NCT06664203Recruiting
Nerve block for arm surgery pain relief
This trial tests a special type of nerve block (called variable volume truncal block) for pain relief during arm, elbow, forearm, hand, or wrist surgery. It may help reduce pain and the need for strong pain medicines.
IstanbulAges 18–65 - NCT06666023Recruiting
A paper test to diagnose orthopedic infections
This trial tests a new paper-based device to quickly diagnose infections after joint replacement or spine surgery. It may help avoid delays from standard lab tests.
Rome, LazioAges 18 years+ - NCT06690658Recruiting
Home arm exercises with a robotic trainer
This trial tests whether a robotic trainer can help people do upper body exercises on their own. It may be a good fit if you can sit without back support and follow simple instructions.
Raanana, IsraelAges 18 years+ - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06869343Recruiting
Early vs. Late Rehab After Shoulder Replacement for Fracture
This study compares starting shoulder rehab early (2 weeks after surgery) versus at the standard time after a reverse total shoulder replacement for a broken shoulder. It aims to see which approach helps you recover better.
Charlottesville, VirginiaAges 50–85 - NCT06877078Recruiting
Podcast for constipation before surgery
This study tests if listening to a podcast about preventing constipation before surgery can help people who are having back, shoulder, knee, or hip surgery. If you are scheduled for one of these surgeries, you may be able to take part.
SilkeborgAges 18 years+ - NCT06904989Recruiting
Helping foot nerve pain from chemo with shoe inserts
This trial tests whether special shoe inserts can reduce foot pain and numbness caused by chemotherapy for breast cancer. It may help you feel better and walk more easily.
GothenburgAges 18 years+ - NCT06991205Recruiting
Web mind-body program for pain and substance use
This trial tests a web-based mind-body program to help people who have ongoing arm or hand pain and also use substances like alcohol or cannabis. It aims to improve resilience and reduce pain without requiring in-person visits.
Boston, MassachusettsAges 18 years+ - NCT07047469Recruiting
Ultrasound-guided spinal anesthesia in orthopedic surgery
This study compares two ways of giving spinal anesthesia (midline vs. paramedian) using ultrasound guidance in adults having orthopedic surgery. The goal is to see which approach is safer and more effective.
SohagAges 18–50 - NCT07098741Recruiting
Physical therapy for low back pain and pelvic tilt
This study looks at different physical therapy treatments for people with chronic, non-specific low back pain and a forward-tilted pelvis (anterior pelvic tilt). It aims to find which type of exercise or therapy works best to improve posture and reduce pain.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 20–40
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Common questions
- Are there clinical trials for orthopedics?
- Yes. Clin2 currently lists 121 recruiting orthopedics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.