Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,535 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Anniston, AlabamaAges 18 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07628127RecruitingPhase 1
Study of VRB-103 with or without ecnoglutide for weight loss
This early-stage trial tests two experimental medications—VRB-103 alone or combined with ecnoglutide—to help people with overweight or obesity lose weight. Both drugs are designed to help control appetite and may offer a new treatment option if you qualify.
MelbourneAges 18–60 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Mobile, AlabamaAges 18 years+ - NCT07369011RecruitingPhase 3
Study of eloralintide for sleep apnea with obesity
This study tests an investigational medication called eloralintide to see if it can improve sleep apnea in people who are overweight or have obesity. You will receive either the study drug or a placebo (inactive shot), and your sleep and weight will be monitored over time.
Cullman, AlabamaAges 18 years+ - NCT07255209RecruitingPhase 3
A study of IBI362 for Chinese teens with obesity or overweight
This trial tests a new medicine, IBI362, to help Chinese adolescents lose weight. It may be an option if you are 12 to 17 years old and have obesity or overweight with a related health condition.
Hangzhou, ZhejiangAges 12–18 - NCT07673900RecruitingPhase 1
Testing a new patch for semaglutide in healthy overweight adults
This trial tests a new skin patch (VX-201) that delivers semaglutide, a medicine used for weight management, compared to a standard injection. It is for healthy overweight or obese adults who are not taking other weight loss medications.
Tempe, ArizonaAges 18–60 - NCT06180837Recruiting
Can longer sleep improve heart health in overweight adults?
This study tests if getting more sleep (7+ hours) can lower certain fats in the blood called ceramides, which are linked to heart disease risk. It's for overweight adults who currently sleep less than 6.5 hours a night.
Salt Lake City, UtahAges 18–45 - NCT07566390RecruitingPhase 1
Testing a new weight-loss medicine in healthy adults
This early-stage study tests a new experimental medicine (NNC0113-5840) to see how it works in people who are overweight or have obesity. Researchers want to understand how the body processes this medicine and whether it's safe before testing it more widely.
Glendale, CaliforniaAges 18–55 - NCT07437079RecruitingPhase 1
Testing a new weight-loss medicine in healthy people
This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.
Lenexa, KansasAges 18–55 - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Chandler, ArizonaAges 18–75 - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Daphne, AlabamaAges 45–99 - NCT07399678RecruitingPhase 1
A study of ALV-100 for overweight people with or without type 2 diabetes
This trial tests a new medication called ALV-100 for safety and how well it works in people who are overweight or have type 2 diabetes. It might help if you have a higher body weight and want to try a new treatment option.
Miami, FloridaAges 18–65 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT07284875RecruitingPhase 3
Ribupatide for weight loss in adults without diabetes
This trial tests a new medication, Ribupatide, to see if it helps people with obesity or overweight who also have weight-related health problems. You cannot have diabetes to join.
Anniston, AlabamaAges 18 years+ - NCT07321886RecruitingPhase 3
Study of eloralintide for people with obesity or overweight
This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.
Tuscaloosa, AlabamaAges 18 years+ - NCT07654972RecruitingPhase 1
Study of a new weight loss drug in healthy people with obesity or overweight
This study tests a new medication (LY4174794) for weight loss in people who are overweight or have obesity. It will help see if the drug is safe and how the body processes it.
San Antonio, TexasAges 18–65 - NCT07665879RecruitingPhase 1
Study of an experimental drug for people with overweight or obesity
This trial tests an experimental drug (Eloralintide) to see if it can help with weight management. It is for people who have a body mass index (BMI) between 25 and 45 and stable weight.
NeussAges 18–70 - NCT07284901RecruitingPhase 3
Weekly injection for diabetes and weight loss
This study tests an experimental once-weekly injection called ribupatide for people with type 2 diabetes and overweight. It aims to help them lose weight and better control their blood sugar.
Cullman, AlabamaAges 18 years+ - NCT07667504Recruiting
Dietary approaches for weight management in type 1 diabetes
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Málaga, MálagaAges 18–65 - NCT04113070Recruiting
Study of childhood weight and early puberty development
This study follows children to see how body weight changes relate to when puberty starts and how it progresses. It may help doctors better understand healthy growth patterns during childhood.
Shanghai, Shanghai MunicipalityAges 6–12
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,535 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.