Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03527420Recruiting
Study of body fat, blood vessels, and DNA changes
This study looks at how having a high body mass index affects blood vessel function and changes in DNA. It may help researchers understand why weight-related health risks happen and how bariatric surgery could help.
Chicago, IllinoisAges 18–50 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT06414096RecruitingPhase 1
Pulsatile FSH study for women with obesity or low ovarian reserve
This study tests a new way to give a fertility hormone (FSH) in pulses through a small tube to see if it helps women with obesity or low egg reserve have better egg development with fewer health risks. It may improve fertility treatment outcomes for these women.
Aurora, ColoradoAges 19–37 - NCT06416969RecruitingEarly Phase 1
Study of fat breakdown in overweight adults
This study looks at how fat cells in the belly release fat. Researchers want to learn more about fat breakdown in people who are overweight or obese. If you join, you may get a drug that helps them measure fat activity.
Rochester, MinnesotaAges 18–65 - NCT06392854RecruitingEarly Phase 1
Fat tissue and insulin in obesity
This early-phase trial tests how fat tissue in different parts of the body responds to insulin. It may help researchers understand why some people with obesity are more prone to health problems like diabetes or heart disease.
Rochester, MinnesotaAges 18–65 - NCT06397729Recruiting
Testing a new tool to support healthy habits in rural clinics
This study is testing a new way to help people improve their heart health by making healthy changes in their daily habits. It focuses on patients in rural primary care clinics who are at higher risk because of their weight.
St Louis, MissouriAges 18–64 - NCT06374875RecruitingPhase 4
Does metabolic surgery reduce liver scarring?
This study tests if weight loss surgery can improve liver fibrosis (scarring) in people with obesity and advanced liver disease. It may help those considering surgery to know if their liver health can get better.
Phoenix, ArizonaAges 18–75 - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT06341179Recruiting
Does more sleep help children learn and manage weight?
This study tests whether helping children sleep longer each night can help them learn better and manage their weight. It is for children ages 6–12 who are above a healthy weight and sleep 9 hours or less per night.
CopenhagenAges 6–12 - NCT04994665Recruiting
Test of fixing the stomach to reduce reflux after sleeve surgery
This study checks whether a surgical “fix” (omentumpexy) can reduce acid reflux after sleeve gastrectomy. It’s mainly for adults having sleeve surgery who have a higher-risk body weight and related health problems.
BayonneAges 18 years+ - NCT06320782Enrolling by invitation
Diet and belly fat study for overweight adults
This study tests how different diets affect belly fat, thigh muscle, and heart health in people who are overweight. It might help you find a way to eat that improves your health.
Recife, PernambucoAges 20 years+ - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06309576Recruiting
Study on body weight regulation using liquid meals
This study tests how the body regulates weight by having participants drink only a special liquid meal for two days. It may help researchers understand weight changes in people with low or high body weight.
Baton Rouge, LouisianaAges 18–40 - NCT06278285Recruiting
GLP-1 drug effect on fat tissue before bariatric surgery
This study looks at how taking a GLP-1 medicine (like Ozempic or Wegovy) affects your fat tissue before bariatric surgery. It compares people who have taken a GLP-1 for at least 3 months to those who never have.
Nice, Alpes-maritimesAges 18 years+ - NCT06292728Recruiting
Study of the ENDOPLY System for Weight Loss
This trial tests a new device called the ENDOPLY system, which is placed inside the stomach through a tube in the mouth to help with weight loss. It is for people who have struggled with dieting and have a BMI between 30 and 40.
BrnoAges 18–60 - NCT06292936Recruiting
Remi for weight regain after weight loss surgery
This study tests if the medication Remi can help people who have gained back at least 5% of their lowest weight after gastric bypass or sleeve gastrectomy. It is meant for those who are not currently using other weight loss drugs and are otherwise healthy enough to participate.
Chicago, IllinoisAges 18–70 - NCT06293703Recruiting
Leg length ratio and weight loss after gastric bypass
This study looks at how the length of different parts of your small intestine affects weight loss after Roux-en-Y gastric bypass surgery. It may help doctors tailor the surgery for better results.
Cleveland, OhioAges 18–70 - NCT06286761Recruiting
Validation of lab tests for metabolism research
This study checks how reliable routine lab tests and research techniques are for metabolism research. It may help you if you are a healthy adult with a stable weight and no major health conditions.
Columbia, MissouriAges 18–75 - NCT06271317Recruiting
Complications after sleeve gastrectomy study
This study looks at complications after a type of weight-loss surgery called sleeve gastrectomy (removing part of the stomach). If you are considering this surgery and meet the weight/health guidelines, you may be able to join to help doctors learn more about risks and recovery.
Nantes, NantesAges 18 years+ - NCT06240208Recruiting
Study of inactivity and appetite in healthy men
This study looks at how two weeks of being inactive (not exercising and walking very little) changes appetite and hunger in healthy, active men. It may help us understand why some people gain weight when they stop being active.
CopenhagenAges 40–55 - NCT06230510Recruiting
Whole vs. low-fat milk study for toddlers
This study compares the health effects of drinking whole milk versus 1% low-fat milk for one year in children aged 23 to 48 months. Researchers want to see which type of milk is better for growth and overall health.
Oakland, CaliforniaAges 1.9 years–4 years - NCT06234332Recruiting
Peking University Birth Cohort in Weifang
This study follows pregnant women and their families in Weifang to learn about health during pregnancy, birth, and early childhood. If you join, you, your husband, and your baby will be part of a long-term research project that tracks your health and development.
Beijing, Beijing MunicipalityAges 18 years+
Hear when a new Overweight or Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.