Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06223555Recruiting
Mixed meal energy study in healthy adults
This study looks at how your body responds to a mixed meal (a test drink or meal) when the calories are either fixed or adjusted to your energy needs. It may help researchers understand how to measure metabolism more accurately.
Phoenix, ArizonaAges 18–99 - NCT06206954Enrolling by invitation
Supporting healthy lifestyle changes for weight loss
This study tests whether a simple lifestyle program helps people lose weight. It involves regular check-ins with your doctor and using a smart scale at home.
Gainesville, FloridaAges 18 years+ - NCT06226077RecruitingPhase 1/Phase 2
Sleep health program for African American adults
This study is testing a culturally tailored program to help African American adults who are overweight and sleep poorly get more sleep. If you join, you'll work with a coach to improve your sleep habits and health.
Minneapolis, MinnesotaAges 21–75 - NCT05777928Recruiting
Tests satiety changes after bariatric surgery revision
This study looks at how feelings of fullness (satiety) change in people getting bariatric surgery—either a sleeve gastrectomy or a revision procedure. It may help improve how well weight-loss stays on track after surgery.
MilanAges 18–65 - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT05338944Recruiting
Dialectal behavior therapy for teens with obesity and low mood
This study tests whether Dialectal Behavior Therapy (DBT)—a structured skills-based counseling program—can help teens make healthier behavior changes. It is for teens who have obesity and mild to moderate symptoms of depression, and it checks whether they can follow the study plan.
Calgary, AlbertaAges 14–17 - NCT05963971Recruiting
Bilingual online program to prevent weight gain in childhood leukemia
This trial tests a bilingual, online program to help children and teens who have ALL (a type of leukemia) stay at a healthy weight during the maintenance phase of treatment. It may help lower the chance of gaining too much weight while on chemotherapy.
New York, New YorkAges 5–21 - NCT06131281Recruiting
Comparing two endoscopic procedures for weight regain after gastric bypass
This study compares two endoscopic procedures used to help people who have regained weight after gastric bypass surgery. The goal is to see which procedure is more effective at reducing the size of the connection between the stomach and intestine to help with weight loss.
Cleveland, OhioAges 18 years+ - NCT06153056Recruiting
Predicting success of stomach sleeve procedure
This study looks at factors that predict weight loss success after a non-surgical stomach reduction procedure (endoscopic sleeve gastroplasty). It may help if you have obesity-related health problems and have not succeeded with diet or lifestyle changes.
ParisAges 18 years+ - NCT06132477RecruitingPhase 4
Study of GLP-1 medicines after weight loss surgery
This study looks at what happens when people taking a GLP-1 medication (like Ozempic) either stop or continue it after weight loss surgery. The goal is to learn whether staying on the medicine helps with long-term weight control.
Columbia, MissouriAges 18 years+ - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06111040Recruiting
Parenting study for food-driven young children
This study tests a program to help parents handle feeding their 4- or 5-year-old child who is very motivated by food. It aims to support healthy eating habits.
Philadelphia, PennsylvaniaAges 4–5 - NCT06105164Recruiting
Brain's Fullness Circuit Study
This study uses brain imaging and mild magnetic stimulation to explore how a brain circuit helps you feel full after eating. It may help us understand eating behaviors and weight regulation.
Belmont, MassachusettsAges 18–65 - NCT06115265Recruiting
Ketogenic diet study for prediabetes and weight loss
This trial tests whether a ketogenic diet can help people with prediabetes or high blood sugar improve their health and lose weight. You eat very low-carb, high-fat foods to see if it lowers your blood sugar and reduces your risk of developing diabetes.
Albuquerque, New MexicoAges 18 years+ - NCT04352244Recruiting
Study of brown fat activity in healthy adults
This study measures how “brown fat” works in the body using planned medical procedures. It looks at healthy adults to understand brown fat activity and what affects it.
Boston, MassachusettsAges 18–75 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT06057597Recruiting
Comparing two types of gastric bypass surgery for weight loss
This trial compares a new version of gastric bypass (with a longer 150cm bypassed segment) to the standard Roux-en-Y gastric bypass to see which leads to better weight loss and health improvements. It is for people with severe obesity who are already scheduled for surgery and want to help find the best procedure.
ParisAges 18–65 - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85 - NCT06043245Enrolling by invitation
Diabetes remission and weight loss surgery
This trial tests whether a specific type of weight loss surgery can help people with type 2 diabetes stop needing diabetes medication. It is for people with a very high body mass index (BMI over 45) who are currently on diabetes pills or insulin.
L'Hospitalet de Llobregat, BarcelonaAges 18–60 - NCT06051591Recruiting
Food FARMacia: Helping families with food worries
This study tests a program called Food FARMacia to help families with young children who sometimes worry about having enough food. The goal is to see if the program can help prevent childhood obesity by providing support and resources.
Stanford, CaliforniaAges 6 months+ - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06003686Recruiting
Spinal cord injury education study for adults
This study is looking at how well a special education program helps people with spinal cord injuries manage their health and daily life after leaving the hospital. It is for adults who recently finished their first rehabilitation stay and have a spinal cord injury from the C5 level or lower.
Washington D.C., District of ColumbiaAges 18–70
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.