Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06020027Enrolling by invitation
Water Is K'é: Healthy Drink Choice Program for Navajo Families
This study helps Navajo families choose water and other healthy drinks instead of sugary ones. It works with families who have young children in early childhood programs.
Window Rock, ArizonaAges 2 years+ - NCT06011499Recruiting
Online lifestyle program for prostate cancer survivors
This study tests an internet-based program to help prostate cancer survivors who are overweight and frail improve their health. You will be assigned to either a lifestyle coaching group or a usual care group, and both groups are followed for about 6 months.
Portland, OregonAges 18 years+ - NCT06003686Recruiting
Spinal cord injury education study for adults
This study is looking at how well a special education program helps people with spinal cord injuries manage their health and daily life after leaving the hospital. It is for adults who recently finished their first rehabilitation stay and have a spinal cord injury from the C5 level or lower.
Washington D.C., District of ColumbiaAges 18–70 - NCT05774652Recruiting
Teen study following mothers from an earlier pregnancy project
This study follows teenagers whose mothers took part in an earlier lifestyle-in-pregnancy study (started in 2007–2010). It may help researchers understand how that earlier study relates to teen health and development.
OdenseAges 13–65 - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT05950282Recruiting
Study of insulin sensitivity differences by age and PCOS status
This study looks at how well the body uses insulin (insulin sensitivity) across different ages, sexes, races, body weights, and whether someone has PCOS. It may help researchers understand why insulin function varies and how PCOS could be linked to metabolic health.
Houston, TexasAges 18 years+ - NCT05972564RecruitingPhase 1/Phase 2
SGLT2 inhibitor for metabolic syndrome and heart health
This study tests whether a diabetes medication called an SGLT2 inhibitor can reduce inflammation in body fat and improve blood vessel function in people with metabolic syndrome. It may help prevent heart disease and other complications.
Nashville, TennesseeAges 18 years+ - NCT05919797RecruitingPhase 4
Weight loss genetics study with naltrexone and bupropion
This trial studies how your genetic makeup and body response may affect weight loss with a medication combination called naltrexone and bupropion. If you qualify, you’ll likely take these medicines and be monitored for safety and changes in weight over time.
New York, New YorkAges 18–65 - NCT05880108Recruiting
Behavior program to help COVID recovery in Veterans
This study tests whether a behavioral (lifestyle) program can improve recovery from COVID-19, especially for Veterans with different body weights. It looks at people who either have never had COVID before or had COVID more than 90 days ago.
Baltimore, MarylandAges Up to 80 years - NCT05881759Recruiting
Food and feeding support program for parents
This study tests whether combining “Food Rx” (food support) with best feeding practices helps parents improve how they feed their 4–8 year old children. If you join, you’ll complete surveys and participate in a parent support program using phone and internet.
Houston, TexasAges 18–64 - NCT05881447Recruiting
Study kidney disease patterns in people in Tanzania
This study looks at how common chronic kidney disease is, how it develops over time, and what risk factors are linked to it. It may help improve how kidney disease is recognized and managed in your community.
Bagamoyo, Coast RegionAges 18–99 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT05880758Recruiting
Studies how yo-yo sleep affects heart and metabolism health
This study looks at what happens to heart-related health and body metabolism when your sleep goes through ups and downs (yo-yo sleep). You may be asked about your sleep habits and health history to see whether your body changes in response to different sleep patterns.
New York, New YorkAges 18–49 - NCT05895968Recruiting
Barbed Suture for Obese Patients Having Neck Surgery
This trial tests a special type of stitch (called barb suture) used during back-of-neck surgery. It is for people who are obese and need surgery for cervical spinal problems, to see if it helps recovery.
Xi'an, Shannxi ProvinceAges 28–85 - NCT05847478Recruiting
Acupressure vs eating plan breaks for specific stomach syndrome
This study compares ear (auricular) acupressure to an intermittent dietary restriction approach in children who have a particular “stomach heat and dampness” pattern from Traditional Chinese Medicine. The goal is to see which method better helps children with certain weight and blood-sugar or cholesterol risks.
ShanghaiAges 6–18 - NCT05866406Recruiting
Time-restricted eating to improve heart and sugar health
This study tests whether eating only within a set daily time window can improve cardiometabolic health (things like blood sugar and heart-related measures). You may be eligible if you have overweight and borderline/high-risk blood sugar but do not have diabetes and can follow the eating and testing rules.
CambridgeAges 25–75 - NCT05861973Recruiting
Smartphone program to support weight loss
This study tests a smartphone app (“SMARTer”) to help adults manage weight. You may be able to join if you have overweight and are not already in a structured weight loss program.
Tallahassee, FloridaAges 18 years+ - NCT05818384Recruiting
Health program for Choctaw youth to improve daily habits
This is a community health program for Choctaw Nation of Oklahoma youth that tries to improve habits related to food, movement, and screen time. It may help you build healthier routines for everyday life.
Durant, OklahomaAges 12–19 - NCT05819853RecruitingPhase 3
Semaglutide to help restart periods in PCOS
This Phase 3 study tests whether semaglutide can help people with polycystic ovary syndrome (PCOS) start ovulating and having more regular periods. You may join with or without metformin, and contraception rules are important because the medicine must not be used during pregnancy.
Aurora, ColoradoAges 12–35 - NCT05838287RecruitingPhase 4
Pioglitazone for heart failure with preserved pumping in type 2 diabetes
This trial tests whether pioglitazone (a diabetes medicine) helps people who have type 2 diabetes and a specific type of heart failure where the heart pumps normally. It may improve heart failure symptoms and function in carefully selected patients.
San Antonio, TexasAges 30–70 - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT05806801Recruiting
Study how weight loss changes the body with or without exercise
This study looks at how your metabolism (how your body uses energy and controls blood sugar/fats) changes during weight loss, comparing weight loss alone versus weight loss plus exercise. It may help researchers understand what body changes happen with different approaches and why.
Ann Arbor, MichiganAges 18–40
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.