Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06218121Recruiting
Frailty detection trial for older adults
This trial aims to improve how frailty is detected in older adults. It tests a new approach to identify frailty early, which could help prevent health problems.
Madrid, Outside of the USAges 62 years+ - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT06290063RecruitingPhase 2
CBD for older adults who use cannabis
This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.
Boulder, ColoradoAges 60 years+ - NCT06485869Recruiting
Virtual reality for better quality of life during chemo
This trial tests if using virtual reality during chemotherapy sessions can improve your quality of life. It's for people who are about to start their first round of IV chemo and have sessions lasting more than 30 minutes.
ChaunyAges 18 years+ - NCT06622369Recruiting
Virtual reality for less fear and pain during circumcision
This trial tests if watching virtual reality during circumcision can help children feel less fear, pain, and anxiety. It may be a good option if your child has not had surgery before, does not have ongoing pain, and does not wear eyeglasses.
IzmirAges 7–12 - NCT07464860Recruiting
Breathwork for older adults after knee surgery
This study tests a breathing exercise program to help older adults recover after knee replacement surgery. Participants practice controlled breathing at home using a smartphone or computer.
Tucson, ArizonaAges 65 years+ - NCT06812247Recruiting
Therapy dog visits for hospitalized trauma patients
This study looks at whether visits from therapy dogs can help people who are in the hospital after a traumatic injury feel better. You must be able to talk to the research team and not be afraid of dogs.
Boston, MassachusettsAges 18 years+ - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07052955Recruiting
Health riddles for less fear and pain in circumcised children
This study tests whether answering health riddles can help reduce fear, anxiety, and pain in children ages 4 to 6 getting circumcised. The goal is to make the experience less stressful for your child.
Gümüşhane, CenterAges 4–6 - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07108192Recruiting
Hand holding and stress ball for cataract surgery comfort
This study tests whether holding a stress ball or having your hand held during cataract surgery can help lower pain and anxiety. It is for people having their first cataract surgery and who are not on certain medications.
SakaryaAges 18 years+ - NCT07130084Recruiting
Virtual reality for first-time planned cesarean births
This trial tests if using virtual reality (VR) during a planned cesarean section can help reduce anxiety and improve the birth experience. It is for women having their first planned cesarean and who own a compatible smartphone or tablet.
BathAges 18 years+ - NCT07203534Recruiting
Virtual reality for pain and anxiety during bone marrow biopsy
This study tests if using a virtual reality headset during and after a bone marrow biopsy can help reduce pain and anxiety. If you are scheduled for this procedure, you may be able to participate.
Charlotte, North CarolinaAges 18 years+ - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT07427862Recruiting
Virtual reality for kids having interventional radiology
This study tests if using virtual reality (VR) during interventional radiology procedures can help children feel more comfortable and less anxious. It is looking for children ages 8 and older who are in the normal range of development.
Los Angeles, CaliforniaAges 8 years+ - NCT07538427Recruiting
Music Therapy for Health in Rural Elder Care
This study explores whether music can improve health and wellbeing in older adults living in rural care facilities. Researchers will work with residents to understand how music might help with mood, memory, and quality of life.
Flagstaff, ArizonaAges Any age - NCT07591324Recruiting
3D-Printed vs. Traditional Space Holders for Kids' Teeth
This study compares two types of dental devices that hold space in a child's mouth after baby molars fall out early. The research tests whether a newer 3D-printed version works as well as or better than the traditional wire-based device.
Ismailia, Ismailia GovernorateAges 7–9 - NCT07638254Recruiting
Buffered vs. Standard Numbing for Dental Pain in Children
This study tests whether a specially prepared numbing medicine works better than standard numbing to reduce pain and anxiety during a dental procedure for children with a painful infected tooth. The goal is to find the gentlest way to numb the area before treatment.
San Luis Potosí City, San Luis PotosíAges 6–12 - NCT07545850Enrolling by invitation
Virtual Reality Glasses to Reduce Pain During IUD Insertion
This study tests whether wearing virtual reality glasses during an IUD insertion procedure can help reduce pain and anxiety. You would wear the glasses during the procedure to see if they help you feel calmer and experience less discomfort.
MalatyaAges 18–49 - NCT07155876Enrolling by invitation
Aromatherapy for comfort during labor
This study tests whether aromatherapy (using pleasant scents) can help with comfort during labor. It is open to pregnant women in labor, even if they end up needing a C-section.
Miami, FloridaAges 18 years+ - NCT06886633Enrolling by invitation
Breathing exercise and cold pack for wound cleaning pain
This study tests whether a simple breathing exercise and a cold pack can help reduce pain and anxiety while a wound is being cleaned (called sharp debridement). If you are having a wound cleaned and feel anxious about it, this may be a way to feel more comfortable.
Gaziantep, GaziantepAges Any age - NCT07650422Recruiting
Virtual Reality to Reduce Anxiety During Cervical Screening
This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.
Adana, AdanaAges 18 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 145 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.