Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07423039Recruiting
Ear acupressure for anxiety and pain during breast cancer surgery
This study tests if pressing on specific points on the ear (acupressure) can help reduce anxiety and pain during breast cancer surgery. It compares acupressure plus standard care to standard care alone, and may be a drug-free way to help you feel calmer before and after your procedure.
StuttgartAges 18–99 - NCT07299474Recruiting
Lavender scent for anxiety and pain during awake ENT procedures
This study tests whether smelling lavender essential oil during an awake ear, nose, or throat procedure can help reduce anxiety and pain. If you qualify, you may receive the lavender scent during your procedure and report how you feel.
Los Angeles, CaliforniaAges 18 years+ - NCT07280416Recruiting
Sleep changes in first year after cancer diagnosis
This study follows people who are newly diagnosed with cancer to see how their sleep changes during the first year. It looks at whether treatments like chemo or immunotherapy affect insomnia.
Le Puy-en-VelayAges 18–80 - NCT07203534Recruiting
Virtual reality for pain and anxiety during bone marrow biopsy
This study tests if using a virtual reality headset during and after a bone marrow biopsy can help reduce pain and anxiety. If you are scheduled for this procedure, you may be able to participate.
Charlotte, North CarolinaAges 18 years+ - NCT07130084Recruiting
Virtual reality for first-time planned cesarean births
This trial tests if using virtual reality (VR) during a planned cesarean section can help reduce anxiety and improve the birth experience. It is for women having their first planned cesarean and who own a compatible smartphone or tablet.
BathAges 18 years+ - NCT07101068Recruiting
Comparing two ways to give dental numbing for kids
This study tests a new dental injector against a traditional syringe to see which one causes less pain and anxiety for children getting numbed for their first cavity treatment.
Cairo, Cairo GovernorateAges 6–8 - NCT07052955Recruiting
Health riddles for less fear and pain in circumcised children
This study tests whether answering health riddles can help reduce fear, anxiety, and pain in children ages 4 to 6 getting circumcised. The goal is to make the experience less stressful for your child.
Gümüşhane, CenterAges 4–6 - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07010003Recruiting
Ear acupressure for anxiety and pain during heart surgery
This trial tests whether small ear acupressure beads can help reduce anxiety and pain in adults having planned heart surgery. The beads are placed on specific ear points and are easy to use.
StuttgartAges 18 years+ - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT06886633Enrolling by invitation
Breathing exercise and cold pack for wound cleaning pain
This study tests whether a simple breathing exercise and a cold pack can help reduce pain and anxiety while a wound is being cleaned (called sharp debridement). If you are having a wound cleaned and feel anxious about it, this may be a way to feel more comfortable.
Gaziantep, GaziantepAges Any age - NCT06812247Recruiting
Therapy dog visits for hospitalized trauma patients
This study looks at whether visits from therapy dogs can help people who are in the hospital after a traumatic injury feel better. You must be able to talk to the research team and not be afraid of dogs.
Boston, MassachusettsAges 18 years+ - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT06723158Recruiting
Virtual reality glasses for oral surgery with sedation
This trial tests if wearing virtual reality (VR) glasses during oral surgery helps patients relax while under IV sedation. It may be a good option if you need sedation for a tooth extraction or other mouth procedure.
Boston, MassachusettsAges 16–65 - NCT06290063RecruitingPhase 2
CBD for older adults who use cannabis
This study tests whether a pure CBD product (Epidiolex) can help older adults who use cannabis occasionally. It looks at how CBD affects people who already take medications for pain, sleep, or mood issues.
Boulder, ColoradoAges 60 years+ - NCT05774002Recruiting
Psychological check-in for teens getting back surgery for scoliosis
This study asks teens with idiopathic scoliosis to complete psychological assessments while planning for elective back surgery. It may help doctors better understand patients’ mental and emotional needs around surgery.
The Bronx, New YorkAges 10–19 - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT05494684Recruiting
Nature-based relaxation for children during blood tests
This study tests whether a nature-based activity can help children aged 5 to 9 feel calmer and less stressed during a blood draw. It aims to make the experience more comfortable for children with long-term illnesses.
OuluAges 5–9 - NCT04526093Recruiting
Study of medical cannabis using patient symptom reports
This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.
Toronto, OntarioAges 19 years+ - NCT07650422Recruiting
Virtual Reality to Reduce Anxiety During Cervical Screening
This study tests whether wearing a virtual reality headset during a colposcopy (a procedure to examine the cervix) can help reduce anxiety, stress, and pain. You would be randomly assigned to either use VR or receive standard care during the procedure.
Adana, AdanaAges 18 years+ - NCT06874452RecruitingPhase 4
Anti-anxiety pill for second cataract surgery
This study tests if giving the anti-anxiety pill alprazolam (XANAX) before your second cataract surgery helps reduce anxiety and improve satisfaction with the procedure.
TaipeiAges 18–80 - NCT07845136Recruiting
Riddles to reduce pain and fear during child cast placement
This study tests whether solving riddles during cast placement helps children feel less pain, fear, and anxiety. It is a simple, non-drug approach that may make the experience more comfortable for your child.
Kilis, CentralAges 6–12 - NCT07624929Enrolling by invitation
Virtual Reality to Reduce Anxiety During Varicose Vein Treatment
This study tests whether wearing a virtual reality headset during varicose vein treatment (a minimally invasive laser procedure on your legs) can help reduce anxiety and pain. You'd use VR while the doctor treats the problematic veins under local anesthesia.
BydgoszczAges 18 years+ - NCT06038409Recruiting
Ketamine therapy for chronic conditions
This trial tests if ketamine can help people with long-term health issues. It aims to find new treatments for chronic conditions that haven't responded well to other therapies.
Helena, MontanaAges 18 years+
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 144 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.