Clinical trials
Pain and Anxiety clinical trials
Below are recruiting pain and anxiety clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07679295Enrolling by invitation
Port needle change: pain, anxiety, and satisfaction
This trial tests if using a stress ball during port needle changes can help reduce pain and anxiety in cancer patients. It aims to improve comfort and patient satisfaction.
SanliurfaAges 18 years+ - NCT02463266Recruiting
PACE/PACENET program outcomes study for people 65+
This study looks at how well the PACE/PACENET care program works for older adults over time. If you join, you’ll provide consent for a check-in about your outcomes about 3 months after the acute (most intense) phase of care ends, with follow-up around 6 months.
Philadelphia, PennsylvaniaAges 65 years+ - NCT07424209Recruiting
Hypnotic communication during heart catheterization study
This study tests whether talking in a special relaxed way (hypnotic communication) during a heart procedure can help you feel calmer and more comfortable. You may be able to join if you are at least 18, can understand Italian, and are already scheduled for a coronary angiogram.
Ponderano, ItalyAges 18 years+ - NCT07533669Recruiting
Sensory room visit before kidney transplant surgery
This study tests whether spending time in a calming sensory room before kidney transplant surgery helps reduce pain, anxiety, and sleep problems. You would visit a specially designed room with soothing sights, sounds, and textures before your operation.
SakaryaAges 18 years+ - NCT07618676Recruiting
Nitrous Oxide vs Lidocaine for Pain Relief During Needle Procedures
This study compares two pain-relief methods—nitrous oxide gas (laughing gas) and lidocaine numbing cream—to see which works better when doctors need to place a needle in your vein. If you've never used nitrous oxide before and are generally healthy, you may be a good fit.
Belgrade, Savski VenacAges 18–65 - NCT07659015Recruiting
Using a hand exercise tool during IV placement
This study tests if using a simple hand-extension rubber band during IV placement can help reduce pain or improve the procedure. It may be an option for right-handed adults getting an IV in specific arm veins.
Konya, MeramAges 18–65 - NCT06924268Enrolling by invitation
Art therapy for mood and symptoms in palliative care
This trial tests whether a single art therapy session can improve mood and reduce symptom burden for patients in a palliative care unit. It aims to see if creative expression can help you feel better emotionally and physically.
Halifax, Nova ScotiaAges 18 years+ - NCT06758973Enrolling by invitation
Turkish pain anxiety scale study
This study is testing a short Turkish questionnaire about how pain affects your emotions. If you have chronic pain (lasting at least 3 months) that happens 4 or more days a week and is at least a 3 out of 10 in intensity, you may be able to help.
Kırşehir, MerkezAges 18–65 - NCT06550323Enrolling by invitation
Virtual reality for pain during chest tube removal
This study tests if using virtual reality can reduce pain, anxiety, and discomfort when a chest tube is removed after heart bypass surgery. If you are between 18 and 65 and have a chest tube after coronary artery bypass surgery, you may be able to join.
ErzurumAges 18–65 - NCT07370974Recruiting
Hypnosis for anxiety before abdominal surgery
This study tests if a short hypnosis session before abdominal surgery can help reduce anxiety. It may be an option if you are scheduled for such a surgery and have no major psychological conditions.
Kenitra, ProvinceAges 18–80 - NCT07113080RecruitingPhase 4
Do Lemongrass and Lavender Help Kids With Dental Shots?
This study tests whether smelling lemongrass and lavender scents can help reduce fear and pain when a child gets a numbing shot at the dentist. It is for children ages 7 to 11 who are healthy and have never been to the dentist before.
Cairo, Cairo GovernorateAges 7–11 - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT07009028Recruiting
Storigami to reduce pain and fear from IV insertion in kids
This study tests a fun storytelling-and-paper-folding method called 'storigami' to see if it helps children feel less pain, fear, and worry when they get an IV. It's for children who need an IV for the first time during this hospital visit.
Izmir, BornovaAges 6–9 - NCT07319806Enrolling by invitation
Two ways to help kids feel better during breathing tube removal
This study tests two different methods to lower pain, fear, and emotional upset when a breathing sample is taken from hospitalized children aged 6 to 12. The goal is to find which approach works best to make the experience easier for your child.
DüzceAges 6–12 - NCT07201480Recruiting
Thinking about death and emotions: a lab study
This study looks at how thinking about death affects feelings of anxiety and sadness. You'll do a short lab task and answer questions.
Cluj-NapocaAges 18–65 - NCT07524049Recruiting
Giving Children a Voice in Pediatric Anesthesia
This study listens to what children, their families, and doctors think about anesthesia care (the medication that puts you to sleep during surgery). Researchers want to understand how to make the experience better and less scary for kids having procedures.
Aarau, Canton of AargauAges 6 years+ - NCT05974384Recruiting
Music during closed treatment to ease wrist fracture pain
This study looks at whether playing music while doctors perform a closed procedure to realign a broken wrist can reduce pain and anxiety. It may help by making the procedure feel calmer for some people.
Sabadell, BarcelonaAges 18–100 - NCT05774002Recruiting
Psychological check-in for teens getting back surgery for scoliosis
This study asks teens with idiopathic scoliosis to complete psychological assessments while planning for elective back surgery. It may help doctors better understand patients’ mental and emotional needs around surgery.
The Bronx, New YorkAges 10–19 - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT07010003Recruiting
Ear acupressure for anxiety and pain during heart surgery
This trial tests whether small ear acupressure beads can help reduce anxiety and pain in adults having planned heart surgery. The beads are placed on specific ear points and are easy to use.
StuttgartAges 18 years+ - NCT06723158Recruiting
Virtual reality glasses for oral surgery with sedation
This trial tests if wearing virtual reality (VR) glasses during oral surgery helps patients relax while under IV sedation. It may be a good option if you need sedation for a tooth extraction or other mouth procedure.
Boston, MassachusettsAges 16–65 - NCT04526093Recruiting
Study of medical cannabis using patient symptom reports
This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.
Toronto, OntarioAges 19 years+ - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT06174662Recruiting
Music for comfort during ICU movement
This study tests whether listening to music during movement exercises (like sitting up or walking) helps reduce discomfort in ICU patients. If you are calm enough and speak Dutch, this might be an option for you.
Wilrijk, AntwerpAges 18 years+
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Common questions
- Are there clinical trials for pain and anxiety?
- Yes. Clin2 currently lists 145 recruiting pain and anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain and anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain and anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.