Clinical trials
Pain Control clinical trials
Below are recruiting pain control clinical trials, each written for real people, not researchers. We’re tracking 260 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06349772RecruitingEarly Phase 1
Pain relief after robotic sleeve gastrectomy: Zynrelef vs Exparel
This trial compares two long-acting pain medicines, Zynrelef and Exparel, to see which works better for pain control after robotic sleeve gastrectomy. The goal is to improve recovery and reduce the need for stronger painkillers.
Lubbock, TexasAges 18–65 - NCT06819956RecruitingPhase 3
Lower-dose ketorolac for pain in the ICU
This trial tests whether a lower dose of the pain medicine ketorolac can safely control pain for people in the intensive care unit (ICU). If you are in the ICU and have pain, this study might help find a better way to treat it.
Edmonton, AlbertaAges 18 years+ - NCT07195422Recruiting
Study of a new device for low back pain relief
This trial tests a wearable device called Japet.W+ to see if it can help reduce chronic low back pain. It might be an option for people who have had lower back pain for a long time and are looking for non-surgical relief.
Clermont-FerrandAges 18–80 - NCT07776275Recruiting
Headache study comparing neck pain patients with healthy people
This study looks at physical differences between people with cervicogenic headache (a headache that starts in the neck), people with chronic neck pain without headache, and healthy controls. By comparing these groups, researchers hope to better understand what causes the headache and which physical features are specific to it.
Istanbul, SefaköyAges 25–60 - NCT06975202Recruiting
Trunk Muscle Activation in Pain-Free Adults
This study checks how reliably trunk muscle activity can be measured in healthy people. It helps researchers understand normal muscle function without pain.
GhentAges 18–65 - NCT07374354Recruiting
Pain and anxiety control for kids with MIH
This study tests a pain-relieving medicine given before dental treatment to see if it helps reduce pain and anxiety in children with molar incisor hypomineralization (MIH), a condition that causes weak enamel on molars and front teeth.
GizaAges 6–12 - NCT07610408Recruiting
Pain Relief Methods After Chest Surgery Nerve Block Wears Off
This study compares different intravenous (IV) pain medications given after a regional anesthetic nerve block stops working in patients having minimally invasive chest surgery. The goal is to find the most effective pain management strategy for recovery.
Ankara, KeçiörenAges 18–80 - NCT06960317Recruiting
Numbing injection for IUD placement pain
This study tests whether a numbing injection (lidocaine) in the cervix can reduce pain during IUD placement. It's for women who have never had a vaginal birth and are getting their first IUD.
La Jolla, CaliforniaAges 18–50 - NCT06910982Enrolling by invitation
Yoga and Mindfulness for Chronic Low Back Pain
This study tests whether a combination of yoga and mindfulness exercises can help reduce chronic lower back pain. It compares this program to usual care, and may be a good fit if your pain is bothersome but you are not too afraid that moving will make it worse.
Karachi, SindhAges 25–45 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06785909Recruiting
Understanding why pregnancy back and pelvic pain persists
This study looks at why some women develop ongoing pain in the lower back or pelvis during pregnancy. It tests how your body's sense of movement, fear of pain, and inflammation might be related. You may join if you are early in a single pregnancy and do not have that pain yet.
HasseltAges 18–40 - NCT07527039RecruitingPhase 4
Nerve Block for Pain Relief During Breast Reduction Surgery
This study tests a special numbing technique (pectoral block) to help control pain after breast reduction surgery in women with very large breasts causing symptoms like neck, shoulder, or back pain. The goal is to see if this nerve block reduces pain better than standard pain control methods.
Roanoke, VirginiaAges 18–75 - NCT07094451Recruiting
Virtual reality for pain during needle procedures
This study tests whether using a virtual reality headset can help reduce pain during ultrasound-guided needle procedures in pregnancy. It may offer a drug-free way to feel more comfortable during the procedure.
New York, New YorkAges 18 years+ - NCT07487987Recruiting
Imagery and exercises for chronic neck pain
This trial tests whether imagining movements (motor imagery) and doing special neck exercises can help people with long-term neck pain. You may be eligible if your neck pain has lasted at least 3 months and is at least moderate, and you haven't had recent neck surgery or therapy.
Konya, KaratayAges 18–65 - NCT06929559Recruiting
How the body responds to walking when expecting pain
This study looks at how your muscles and walking pattern change when you expect a mild pain. It may help researchers understand how the body adapts to pain anticipation in healthy people.
AmiensAges 18–35 - NCT07185724RecruitingPhase 4
Ketorolac for fresh embryo transfer in IVF
This trial tests whether a medicine called ketorolac (a type of NSAID, similar to ibuprofen) can improve outcomes when you have a fresh embryo transfer during IVF. It may help reduce cramping or inflammation that could affect implantation.
Iowa City, IowaAges 18–37 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07153003Enrolling by invitationPhase 4
Tramadol and oxycodone vs oxycodone alone for joint pain
This trial tests if taking two pain relievers (tramadol and oxycodone) together works better than oxycodone alone to control pain after knee or hip replacement surgery. It aims to find a more effective way to manage pain with fewer side effects.
Rochester, MinnesotaAges 18 years+ - NCT04226716Recruiting
Studying pelvic pain causes in multiple or first pregnancies
This study looks at why pelvic girdle pain happens during pregnancy, focusing on body sensing (proprioception), stress factors, and inflammation. You may be able to help researchers understand the causes and who is most at risk.
HasseltAges 18–40 - NCT02991625Enrolling by invitation
Brain scan study to find markers for chronic back pain
This study uses brain imaging (MRI scans) to look for “biomarkers” (measurable signs) that may relate to chronic low back pain. It compares people with long-lasting back pain to healthy volunteers to understand what brain patterns are linked to pain.
Halifax, Nova ScotiaAges 18–75 - NCT07352384Enrolling by invitation
Brain stimulation for chronic face and mouth pain
This trial tests if a non-invasive brain stimulation technique (called TMS or tDCS) can help reduce long-lasting pain in the face, jaw, or mouth. It's for people who have tried other treatments without enough relief.
Almada, Setúbal DistrictAges 18–75 - NCT03823534RecruitingPhase 3
Study pain control after preventive femur bone surgery
This Phase 3 study tests a pain medicine plan used after preventive surgery to place a metal rod inside the thigh bone (femur) before a fracture happens. The goal is to find an approach that controls post-surgery pain while being safe for the right patients.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for pain control?
- Yes. Clin2 currently lists 260 recruiting pain control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.