Clinical trials
Pain Control clinical trials
Below are recruiting pain control clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03823534RecruitingPhase 3
Study pain control after preventive femur bone surgery
This Phase 3 study tests a pain medicine plan used after preventive surgery to place a metal rod inside the thigh bone (femur) before a fracture happens. The goal is to find an approach that controls post-surgery pain while being safe for the right patients.
St Louis, MissouriAges 18 years+ - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06910540Recruiting
Acu-TENS for pain and stress in IVF
This trial tests if acu-TENS, a needle-free acupressure device, can reduce pain and stress in women before and during an embryo transfer procedure. It's designed for women going through IVF treatment.
Hong KongAges 18 years+ - NCT07293975Recruiting
Pain relief during brace removal with TENS or vibration
This study tests two drug-free methods—gentle electrical stimulation (TENS) and high-frequency vibration—to see if they can reduce pain when braces are removed.
BaghdadAges 15–35 - NCT06113211RecruitingPhase 4
Non-opioid pain control after fracture surgery
This trial tests a combination of non-opioid medications to manage pain after surgery for a broken bone, aiming to reduce or avoid the use of opioids. It may help you control pain without the risks of strong painkillers.
Detroit, MichiganAges 18–80 - NCT06617949RecruitingEarly Phase 1
Pain Control Study for New Mothers on Opioid Medication
This study looks at better ways to manage pain after childbirth for mothers who are taking medication for opioid use disorder. It aims to find which pain control method works best and is safest for you and your baby.
Milwaukee, WisconsinAges 18–40 - NCT06810336RecruitingEarly Phase 1
Pain control after brain surgery: methadone vs remifentanil
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Charlottesville, VirginiaAges 18–65 - NCT07288047Recruiting
Virtual reality for pain during early abortion
This study tests if using a virtual reality headset during a first trimester procedural abortion can help reduce pain and anxiety. You may be eligible if you are planning to have an abortion at Planned Parenthood of Western Pennsylvania and meet the criteria below.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04399707Recruiting
Nerve-pain device study for pain after C-section
This study tests whether a small skin electrical nerve stimulator (called TENS) can reduce pain after a planned or not-urgent C-section. You may be more likely to have less pain and use fewer pain medicines if the TENS helps you.
Honolulu, HawaiiAges 18 years+ - NCT07851233Enrolling by invitation
Patient education on sling use after shoulder surgery
This study looks at how different ways of teaching patients about sling use after shoulder surgery may affect their recovery. If you join, you may receive extra education materials to help you use your sling correctly.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07794527Recruiting
Nerve blocks to improve recovery after heart bypass surgery
This study tests whether giving multiple nerve blocks (numbing injections near nerves) during off-pump heart bypass surgery can improve your recovery and pain control. It aims to see if these blocks help you feel better and recover faster after surgery.
CairoAges 18–65 - NCT07773155RecruitingPhase 4
Pain control after hand or wrist surgery: nerve block with or without ketorolac
This study tests two different pain relief methods after hand or wrist surgery: a nerve block alone versus a nerve block plus an anti-inflammatory medication called ketorolac. The goal is to see which approach provides better pain control with fewer side effects.
Chicago, IllinoisAges 18 years+ - NCT07675473RecruitingPhase 4
Pain relief before lung nodule localization
This trial tests giving a pain medicine (parecoxib) before a CT-guided lung nodule procedure to see if it reduces pain during the treatment. It's for people with non-small cell lung cancer who need a wire placed in their lung before surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT07528300Recruiting
Acupuncture for pain relief in muscle injury patients
This study tests whether a type of acupuncture called "battlefield acupuncture" can help reduce pain in people hospitalized with rhabdomyolysis—a serious muscle injury that causes muscle breakdown and pain. Researchers want to see if this treatment helps patients feel better while they're in the hospital.
TAMC, HawaiiAges 18–99 - NCT07513012Enrolling by invitation
Pain Relief Methods After Gallbladder Removal Surgery
This study compares two ways of numbing the abdomen during gallbladder removal surgery to see which one works better for pain relief. One method numbs one side of your belly, and the other numbs both sides.
Lahore, Punjab ProvinceAges 18–80 - NCT06778954Recruiting
Pain control gel after stomach cancer surgery
This trial tests a gel (ropivacaine in a special polymer) applied during stomach cancer surgery to reduce pain after the operation. The goal is to help patients recover with less pain and fewer side effects from painkillers.
SeoulAges 20 years+ - NCT06746168Recruiting
Better pain control after knee replacement surgery
This study tests a new way to manage pain after total knee replacement. It aims to see if a specific local pain block can reduce the need for strong opioids and improve recovery.
Hasselt, LimburgAges 18–85 - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79 - NCT07325994Recruiting
Pain control during hysteroscopy for women with infertility
This trial tests if using calming words (verbal analgesia) during a hysteroscopy can reduce pain compared to standard care. It is for women with primary infertility who need this procedure to check the uterus.
GizaAges 18–40 - NCT07268118RecruitingPhase 2
Pain relief for cervical ripening balloon in labor
This study tests if using lidocaine gel on the cervix before placing a ripening balloon can reduce pain for pregnant women at full term. It may help women who want this balloon to start labor feel more comfortable.
Boston, MassachusettsAges 18 years+ - NCT03913819Recruiting
Standard treatment for bladder problems caused by substance abuse
This trial tests how well a set “standard” treatment plan works for people with bladder emptying problems caused by substance abuse. You might consider it if you have this specific type of bladder issue and can follow the treatment plan.
ShatinAges Any age - NCT07145346Enrolling by invitationPhase 4
Suzetrigine for pain relief after multiple rib fractures
This trial tests a new medicine, suzetrigine, for managing acute pain in adults who have broken three or more ribs from a blunt injury. It aims to see if this painkiller works well and is safe for you.
Orange, CaliforniaAges 18 years+ - NCT07125833Recruiting
Cold therapy for shoulder replacement pain
This trial tests if freezing a nerve near the shoulder before surgery can reduce pain after a reverse total shoulder replacement. It may help you recover with less discomfort.
Rockwall, TexasAges 30–85
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Common questions
- Are there clinical trials for pain control?
- Yes. Clin2 currently lists 253 recruiting pain control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.