Clinical trials · Florida
Pain clinical trials in Florida
We’re tracking 95 recruiting pain studies with a site in Florida — including Phase 1, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT07207174Recruiting
Mindfulness vs CBT for chronic pain relief
This study compares two non-drug treatments—mindfulness training and cognitive-behavioral therapy—to see which helps adults with chronic pain better. Both aim to reduce pain and improve quality of life.
Tallahassee, FloridaAges 18 years+ - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Clermont, FloridaAges 18 years+ - NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Jacksonville, FloridaAges 18–80 - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Brandon, FloridaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Jacksonville, FloridaAges birth–20 years - NCT06717308Recruiting
Testing a gentler adhesive drape for wound therapy
This trial compares a special adhesive drape (the switchable one) with the standard drape during negative pressure wound therapy (a treatment that uses suction to help heal wounds after surgery). The goal is to see if the new drape causes less pain when removed.
Miami, FloridaAges 18 years+ - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Daytona Beach, FloridaAges 45–80 - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Jacksonville, FloridaAges 18 years+ - NCT04733599Recruiting
Spinal cord stimulation for long-term arm nerve pain
This trial tests whether a high-frequency spinal cord stimulator can reduce long-term nerve pain in the arm after a brachial plexus injury. It may help people whose pain has lasted at least 3 months despite standard treatments.
Jacksonville, FloridaAges 18 years+ - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+ - NCT07704853Recruiting
Neck joint study for healthy adults 18–35
This study tests a quick neck move (like a chiropractic adjustment) to see how it affects the small joints in your neck. It may help researchers understand how such moves work on healthy tissue.
Fort Myers, FloridaAges 18–35 - NCT05561595Recruiting
Reducing health-related stigma through group support
This trial tests a virtual group program to help people cope with health-related stigma from conditions like obesity, cancer, HIV, diabetes, skin disease, or chronic pain. It aims to reduce internalized stigma and improve well-being.
Gainesville, FloridaAges 18 years+ - NCT07506018Recruiting
MucoLock for mouth pain caused by stomatitis
This study tests a new mouth rinse, MucoLock, to see if it can help people with severe mouth pain (stomatitis). If you have burning or painful mouth sores that rate very high on a pain scale, this trial may offer a new treatment option.
Miami, FloridaAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Gainesville, FloridaAges 18 years+ - NCT04305743RecruitingPhase 4
Compare pain after 5 vs 20 bladder botox injections
This study looks at how much discomfort you have after receiving bladder Botox injections, comparing a smaller (5) dose vs a larger (20) dose. It’s only for certain overactive bladder conditions and specifically when the procedure is done without sedation or special anesthesia.
Tampa, FloridaAges 18 years+ - NCT05110989Recruiting
Registry study of pain relief after freezing intercostal nerves
This study collects real-world information about how well freezing (cryoablation) of the intercostal nerves helps with pain after a procedure. It may help doctors understand outcomes and improve care for future patients.
Orlando, FloridaAges 12 years+ - NCT05127265Recruiting
AI and sensors to monitor patients in the ICU
This study uses AI and sensor data to better monitor people while they are in an intensive care unit (ICU). It may help teams notice changes sooner and improve care for ICU patients.
Gainesville, FloridaAges 18 years+ - NCT05254574RecruitingPhase 1
Acoustic therapy for ongoing joint pain from osteoarthritis
This Phase 1 study tests a sustained acoustic medicine device to help reduce pain from osteoarthritis (wear-and-tear arthritis) in joints like knees or hips. Because it’s early-stage research, you may be asked to follow strict rules about pain medicines and device use while the team monitors safety and comfort.
Tampa, FloridaAges 35–85 - NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Jupiter, FloridaAges 18 years+ - NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
Miami, FloridaAges 18 years+ - NCT05737121RecruitingPhase 2
Study drug for bladder pain compared with lidocaine, heparin, or placebo
This Phase 2 trial tests VNX001 to see if it helps people with interstitial cystitis/bladder pain syndrome (IC/BPS) compared with its separate ingredients (lidocaine and heparin) or a placebo (inactive treatment). You may be eligible if you have had IC/BPS for months and recently had a moderate-to-severe bladder pain flare.
Tampa, FloridaAges 18 years+ - NCT05773482Recruiting
Breathing and attention training for fibromyalgia pain
This study tests whether breathing and attention exercises can change how your body controls pain in people with fibromyalgia. It may help you learn non-medication ways to influence pain signals and improve comfort.
Gainesville, FloridaAges 18–70 - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
St. Petersburg, FloridaAges 12–17 - NCT06418958Recruiting
Heat from dental light on healthy teeth
This trial measures how much the temperature rises inside a healthy tooth when a dental curing light is used. It helps dentists understand if certain light wavelengths could be safer for teeth.
Gainesville, FloridaAges 21–35
Pain trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting pain studies listed above.
- University of Florida · 4 studies
- Conquest Research · 2 studies
- Louis J. Raso, MD, PA · 2 studies
- Mayo Clinic · 2 studies
- UF Health · 2 studies
- Absolute Medical Center, LLC
- Advanced Interventional Pain Management and Research Clinic, Inc.
- AdventHealth Orlando
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Florida?
- Yes. We're currently tracking 95 recruiting pain studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.