Clinical trials · Florida
Pain clinical trials in Florida
We’re tracking 89 recruiting pain studies with a site in Florida — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Florida
- NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT01719055Recruiting
Long-term follow-up for Boston Scientific pain nerve stimulation
This study looks at how well a Boston Scientific nerve stimulation device works over the long term for pain in everyday care. You may be able to join if you’re already being set up to use one of these approved systems and can reliably report your pain outcomes.
Clermont, FloridaAges 18 years+ - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Brandon, FloridaAges 18 years+ - NCT04305743RecruitingPhase 4
Compare pain after 5 vs 20 bladder botox injections
This study looks at how much discomfort you have after receiving bladder Botox injections, comparing a smaller (5) dose vs a larger (20) dose. It’s only for certain overactive bladder conditions and specifically when the procedure is done without sedation or special anesthesia.
Tampa, FloridaAges 18 years+ - NCT05504499Recruiting
Test a new implant for low back pain with mild narrowing
This trial studies a new spine implant placed between the bones to help relieve low back pain. You may be a candidate if imaging shows mild-to-moderate spinal narrowing and you’ve already tried non-surgical treatments for at least 3 months.
Jupiter, FloridaAges 18 years+ - NCT07645989Recruiting
Registry tracking long-term outcomes after MuseCell treatment
This registry follows patients who have received Dezawa MuseCells (a type of cell therapy) to understand how well the treatment works over 5 years. You'll complete online surveys about your health and progress periodically.
North Palm Beach, FloridaAges Up to 89 years - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Jacksonville, FloridaAges 18 years+ - NCT07500012Recruiting
Ear nerve stimulation for breast cancer pain
This study tests whether gentle electrical stimulation of a nerve in your ear (called taVNS) can help reduce pain and improve symptoms for breast cancer survivors. You would need to have finished your main treatments, have ongoing pain, and be willing to provide stool samples and undergo brain scans.
Tallahassee, FloridaAges 18–79 - NCT07506018Recruiting
MucoLock for mouth pain caused by stomatitis
This study tests a new mouth rinse, MucoLock, to see if it can help people with severe mouth pain (stomatitis). If you have burning or painful mouth sores that rate very high on a pain scale, this trial may offer a new treatment option.
Miami, FloridaAges 18 years+ - NCT07489937Recruiting
Arm exercise effects on the shoulder tendon
This study compares how two different arm exercises affect the shoulder tendon (supraspinatus) in people with and without shoulder pain. It may help find better ways to exercise without causing injury.
Gainesville, FloridaAges 18–45 - NCT07481630RecruitingPhase 3
Testing a new medicine for weight loss and knee pain
This study tests if a new medicine called NNC0487-0111 can help people with extra weight and knee osteoarthritis lose weight and reduce knee pain. If you have knee pain most days and are willing to stop pain relievers for short periods, you may be able to join.
Hollywood, FloridaAges 18 years+ - NCT07437469Recruiting
Binaural beats for pain and anxiety after surgery
This trial tests if listening to binaural beats (a type of sound therapy) after hip or knee replacement surgery can help reduce pain and anxiety. You would receive the sound therapy through headphones while in the recovery room.
Miami, FloridaAges 18–99 - NCT07401134RecruitingPhase 4
Pain relief study after vaginal surgery using witch hazel and spray
This trial tests a pain relief routine using witch hazel pads and a numbing spray after vaginal surgery. The goal is to see if using these products together helps with recovery and reduces the need for stronger pain medicine.
Miami, FloridaAges 18 years+ - NCT05254574RecruitingPhase 1
Acoustic therapy for ongoing joint pain from osteoarthritis
This Phase 1 study tests a sustained acoustic medicine device to help reduce pain from osteoarthritis (wear-and-tear arthritis) in joints like knees or hips. Because it’s early-stage research, you may be asked to follow strict rules about pain medicines and device use while the team monitors safety and comfort.
Tampa, FloridaAges 35–85 - NCT07353931RecruitingPhase 3
Study of eloralintide for knee osteoarthritis pain in people with overweight or obesity
This trial tests an investigational drug called eloralintide to see if it can reduce knee pain in people with osteoarthritis who also have overweight or obesity. You may be able to join if you have knee osteoarthritis, a BMI of 27 or higher, and have tried to lose weight with diet before.
Jacksonville, FloridaAges 18 years+ - NCT07298408RecruitingPhase 1/Phase 2
CBD for Diabetic Nerve Pain: A Pilot Study
This trial tests whether a daily dose of CBD (a cannabis compound) can help reduce nerve pain from type 2 diabetes. It's a small, early study to see if it's safe and effective.
Tallahassee, FloridaAges 40–70 - NCT07257029RecruitingPhase 2
Ketotifen Cream for Vulvar Pain
This trial tests a topical cream called ketotifen for treating a type of vulvar pain (secondary provoked vestibulodynia). The cream may help reduce pain at the vaginal opening, and you would apply it daily for several months.
Tampa, FloridaAges 18 years+ - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT07212036Recruiting
Ultrasound for elbow fractures in children
This study uses ultrasound, a sound-wave imaging tool, to diagnose elbow fractures in children. It aims to see if ultrasound works as well as X-rays, so your child might avoid radiation.
Orlando, FloridaAges Up to 18 years - NCT06977100Recruiting
Journaling study for jaw pain with other chronic pain conditions
This study tests if a journaling program can help people with jaw pain and at least one other chronic pain condition (like fibromyalgia, IBS, or migraines). You will write about your thoughts and feelings to see if it reduces pain and improves well-being.
Gainesville, FloridaAges 18–80 - NCT06965920Enrolling by invitation
Spinal pain and balance study using gentle chiropractic care
This study tests a gentle chiropractic technique called flexion distraction to see if it improves how well you move and balance while standing. It may help if you have spinal pain and can stand with mild to moderate pain.
West Palm Beach, FloridaAges 18–100 - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Daytona Beach, FloridaAges 45–80 - NCT06807866RecruitingPhase 4
Duloxetine for pain after hip replacement surgery
This trial tests if duloxetine, a medication that helps with nerve pain, can reduce pain after hip replacement surgery. It may help patients who are having a first-time total hip replacement.
Miami, FloridaAges 18 years+
Pain trials by city in Florida
Where these studies are running in Florida
Institutions with a site for the recruiting pain studies listed above.
- University of Florida · 3 studies
- Conquest Research · 2 studies
- Advanced Interventional Pain Management and Research Clinic, Inc.
- Advanced Res for Health Improve
- Ambros Clinical Trial Site
- Angels Clinical Research Institute
- Arrow Clinical Trials LLC
- Bioreset Medical
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Florida?
- Yes. We're currently tracking 89 recruiting pain studies with a site in Florida, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Florida?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Florida to take part?
- Not necessarily. These studies have a site in Florida, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Florida regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.