Clinical trials · Pennsylvania
Pain clinical trials in Pennsylvania
We’re tracking 67 recruiting pain studies with a site in Pennsylvania — including Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06559852Recruiting
Yoga for endometriosis pain relief study
This study tests whether a 12-week yoga program can reduce pain in women with endometriosis. It requires that your diagnosis was confirmed by surgery and that you’re not already doing yoga.
Hershey, PennsylvaniaAges 18–45 - NCT06539741Recruiting
Ibuprofen response study for wisdom tooth removal
This study looks at how people respond to ibuprofen after having one or more impacted wisdom teeth removed. It aims to understand why pain relief varies between individuals.
Philadelphia, PennsylvaniaAges 18 years+ - NCT02463266Recruiting
PACE/PACENET program outcomes study for people 65+
This study looks at how well the PACE/PACENET care program works for older adults over time. If you join, you’ll provide consent for a check-in about your outcomes about 3 months after the acute (most intense) phase of care ends, with follow-up around 6 months.
Philadelphia, PennsylvaniaAges 65 years+ - NCT06350409Recruiting
Opioid use after surgery in teens
This study looks at how teens aged 12–17 use opioids after a scheduled surgery. It aims to understand outcomes and help improve pain management.
Philadelphia, PennsylvaniaAges 12–17 - NCT02844751RecruitingPhase 2
Regenerative knee cell therapy for arthritis pain and swelling
This Phase 2 study tests a patient’s own (autologous) regenerative cell treatment to reduce knee pain and inflammation from osteoarthritis. It mainly looks at whether the treatment is safe and whether it can improve symptoms over time.
Grove City, PennsylvaniaAges 18–90 - NCT02844764RecruitingPhase 2
Cell therapy test for hip osteoarthritis pain and swelling
This trial tests an “autologous” regenerative cell treatment, meaning cells taken from you, to reduce hip osteoarthritis pain and inflammation. It checks safety first and looks for improvements in how you feel and move.
Grove City, PennsylvaniaAges 18–90 - NCT02844738RecruitingPhase 2
Cell therapy for shoulder osteoarthritis pain and inflammation
This trial tests a treatment using your own (autologous) regenerative cells to reduce pain and inflammation from shoulder osteoarthritis. It may help people with long-lasting shoulder pain, but you must meet several health and medication timing requirements.
Grove City, PennsylvaniaAges 18–90 - NCT06013878Recruiting
Testing a tool for caregivers who help with transfers
This study tests a special instrument to measure how caregivers help people with physical disabilities move from one place to another (transfers). It may help improve safety and technique for both caregivers and care recipients.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05991453Recruiting
Recovery after IV vs. inhaled anesthesia for non-cardiac surgery
This trial compares recovery after two types of general anesthesia: one given through an IV (propofol) and one inhaled as a gas. It aims to see which approach leads to a smoother recovery for people having non-cardiac surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT05722002RecruitingPhase 4
Compare pain-med plans after low-risk surgery
This study tests which pain-medication plan works best and has the fewest side effects after certain low-risk surgeries. You may be assigned to receive opioid-based, NSAID-based, or acetaminophen-based pain control depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05658575RecruitingPhase 2/Phase 3
Tablets to treat sudden gout flare pain
This trial studies dapansutrile tablets (OLT1177) to see how well they work for people in the first 4 days of an acute gout flare. It may help reduce pain and inflammation in the specific joint where your gout is flaring.
Duncansville, PennsylvaniaAges 18 years+ - NCT05437575RecruitingPhase 3
Testing pain medicine given before arrival to a trauma center
This study tests whether giving pain medicine soon after an injury (before you reach the trauma center) improves comfort and care. You might be eligible if you’re transported to a participating trauma center and meet specific shock and pain levels.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04984291Recruiting
Study of shoulder replacement implants for eligible adults
This trial looks at a specific shoulder replacement implant and follow-up care for people who need a shoulder arthroplasty (shoulder replacement) for certain joint problems or fractures. You may be a candidate if you can take part in required visits and your shoulder muscles and bone are suitable.
Philadelphia, PennsylvaniaAges 20 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Exton, PennsylvaniaAges 18 years+ - NCT04679844Recruiting
Test bone putty for back fusion versus bone graft alternatives
This study compares a ready-to-use bone putty to standard bone graft materials (with or without your own bone) during back fusion surgery for unstable lower back problems. It looks at whether the putty works as well or better to help the bones fuse and heal.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Hershey, PennsylvaniaAges birth–20 years - NCT03434392Recruiting
Testing pain-sensing to predict treatment response in chronic pancreatitis
This study uses a special pain-testing method to better predict how people with chronic pancreatitis-related pain (or similar conditions) will respond to treatment. It may help doctors choose therapies that work better for each person’s type of pain.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Danville, PennsylvaniaAges 18 years+
Pain trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting pain studies listed above.
- VivaTech International, Inc. · 3 studies
- Rothman Orthopaedic Institute · 2 studies
- Allegheny Health Network (AHN) Allegheny General Hospital
- Altoona Research
- Center for Interventional Pain & Spine
- Children's Hospital of Philadelphia
- Department of Psychiatry (Center for Psychotherapy Research), University of Pennsylvania
- Geisinger Medical Center
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Pennsylvania?
- Yes. We're currently tracking 67 recruiting pain studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.