Clinical trials · Texas
Pain clinical trials in Texas
We’re tracking 108 recruiting pain studies with a site in Texas — including Early Phase 1, Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT07632820RecruitingPhase 4
Nerve Block vs. Injection for Upper Back Muscle Pain
This study compares two ways to treat chronic muscle pain in the upper back: a nerve block (numbing injection near the spine) and trigger point injections (shots directly into painful muscle knots). The goal is to see which approach works better for long-lasting relief.
Houston, TexasAges 18–80 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT07538570RecruitingPhase 4
Pain Management After Knee Replacement Surgery
This study tests different pain treatments for patients undergoing total knee replacement surgery. The goal is to find the most effective way to manage pain after this common procedure.
Bellaire, TexasAges 18–80 - NCT07532070Recruiting
Exercise and Therapy for Chronic Pain and Sleep Problems
This study tests whether exercise, talk therapy for sleep problems, or both together can help people with long-term back, hip, or knee pain who also struggle with sleep. You'll attend video appointments and try one of these approaches for several weeks.
San Antonio, TexasAges 18 years+ - NCT07507422Recruiting
Post-market study of Inceptiv spinal cord stimulation
This study follows people receiving Inceptiv, a spinal cord stimulator from Medtronic, to see how well it works over time. It is for adults with chronic back or limb pain who have not tried spinal cord stimulation before.
Houston, TexasAges 18 years+ - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Austin, TexasAges 18 years+ - NCT06414356RecruitingPhase 4
Ketamine for nerve pain and PTSD in military personnel
This study tests whether ketamine infusions can help with ongoing nerve pain and PTSD symptoms. It's for active-duty service members, veterans, and retirees who have had moderate nerve pain for at least 3 months.
San Antonio, TexasAges 18–70 - NCT07231419RecruitingPhase 3
Study of suzetrigine for diabetic nerve pain
This trial tests an experimental pain drug called suzetrigine for people with diabetic peripheral neuropathy (nerve damage from diabetes that causes pain in the feet and legs). It aims to see if the drug can safely reduce pain over time.
Lewisville, TexasAges 18–80 - NCT07226258RecruitingPhase 3
Testing SL1002 for knee pain caused by osteoarthritis
This trial tests a study drug called SL1002 to see if it reduces knee pain from osteoarthritis. It may be an option for people with chronic knee pain who haven't found enough relief from current treatments.
Bellaire, TexasAges 40 years+ - NCT07197645RecruitingPhase 1
Samarium for pain from bone cancer
This trial tests a new radioactive drug (samarium) given once to reduce severe bone pain from cancer that has spread to the bones. It is for people whose pain is not controlled by current treatments and who cannot have standard radiation.
Houston, TexasAges 18 years+ - NCT07116109Recruiting
Brain Stimulation Plus Therapy for Pain and PTSD
This study tests whether a brain-stimulation headband (called tDCS) combined with a proven talk therapy for PTSD can help reduce both chronic pain and PTSD symptoms. It is for adults who have had chronic pain for at least 6 months and also have PTSD.
Houston, TexasAges 21 years+ - NCT07006675RecruitingPhase 3
NSAIDs for Tibia Fracture Pain and Healing Study
This study tests whether NSAID pain relievers (like ibuprofen) affect bone healing after a broken tibia and if they can help reduce the need for stronger painkillers. If you qualify, you could help doctors learn the safest way to manage pain after this common injury.
Houston, TexasAges 18–80 - NCT06968689Recruiting
Brain activity study for experimental and chronic pain
This study uses MRI and EEG to look at brain connections involved in pain. It may help us understand how the brain processes pain and could lead to better treatments.
Houston, TexasAges 18–60 - NCT06940063Recruiting
Music therapy for chronic low back pain
This trial tests whether an active music-based program can help reduce chronic low back pain. It is for adults aged 18 to 65 whose pain has lasted at least 3 months and has been present on most days.
Denton, TexasAges 18–65 - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06661850Recruiting
New imaging test to guide lower back surgery decisions
This study tests a new imaging tool called Nociscan to see if it helps doctors decide who will benefit from lumbar spine surgery for low back pain. It may help predict surgical outcomes and guide treatment.
Plano, TexasAges 18–70 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Dallas, TexasAges 18–80 - NCT06628908RecruitingPhase 3
Study of suzetrigine for painful diabetic nerve damage
This trial tests an experimental medicine called suzetrigine to see if it can safely reduce pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It might be an option if you have had daily pain in both legs and current treatments haven't worked well enough.
Dallas, TexasAges 18–80 - NCT06602271RecruitingPhase 3
Study of PF614 for Pain After Tummy Tuck Surgery
This study tests a new painkiller called PF614 for pain after tummy tuck surgery. It compares the study drug to a placebo (a pill with no medicine) to see how well it works and how safe it is.
Houston, TexasAges 18–75 - NCT06574269RecruitingPhase 2
Study on TLC590 for pain after surgery
This trial tests a new pain medicine, TLC590, for people having one of several common surgeries, like bunion removal, hernia repair, breast augmentation, knee replacement, or tummy tuck. The goal is to see if it helps manage pain after the procedure.
Bellaire, TexasAges 18–70 - NCT06559215RecruitingPhase 2
Pain management with Exparel after knee surgery in teens
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
Frisco, TexasAges 13–21 - NCT06536504Recruiting
Music before brain surgery for stress and pain
This study looks at whether listening to live or recorded music before brain or spine surgery can help reduce stress, improve mood, and lessen pain. You may be able to join if you are scheduled for neurosurgery and can hear and speak English.
Houston, TexasAges 18 years+ - NCT06354699Recruiting
Pain after surgery in children: a long-term study
This study looks at children who have certain types of surgery to understand who might have ongoing pain, what causes it, and how it affects them over time.
Dallas, TexasAges Up to 16 years - NCT06349772RecruitingEarly Phase 1
Pain relief after robotic sleeve gastrectomy: Zynrelef vs Exparel
This trial compares two long-acting pain medicines, Zynrelef and Exparel, to see which works better for pain control after robotic sleeve gastrectomy. The goal is to improve recovery and reduce the need for stronger painkillers.
Lubbock, TexasAges 18–65
Pain trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting pain studies listed above.
- Legent Orthopedic and Spine Hospital · 2 studies
- Methodist Dallas Medical Center · 2 studies
- San Antonio Clinical Trials · 2 studies
- The University of Texas Health Science Center at Houston · 2 studies
- The University of Texas MD Anderson Cancer Center · 2 studies
- Advanced Spine and Pain Center
- Amarillo Medical Specialists LLP
- Austin Orthopedic Institute
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Pain trials in other states
Common questions
- Are there pain clinical trials in Texas?
- Yes. We're currently tracking 108 recruiting pain studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.