Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06758973Enrolling by invitation
Turkish pain anxiety scale study
This study is testing a short Turkish questionnaire about how pain affects your emotions. If you have chronic pain (lasting at least 3 months) that happens 4 or more days a week and is at least a 3 out of 10 in intensity, you may be able to help.
Kırşehir, MerkezAges 18–65 - NCT06754111Enrolling by invitation
Can the birth environment help with pain and fear?
This study looks at how the birth environment (like a calm, comfortable room) affects pain, fear, how you give birth (vaginal or C-section), and how long labor lasts. It's for first-time mothers who are healthy and not high-risk.
Burdur, BucakAges 18–35 - NCT06721000Enrolling by invitation
Patient-controlled vs. standard epidural pain relief
This trial compares two types of epidural pain management during surgery. It tests whether letting you control your pain medication yourself works better than the standard method.
Karachi, SindhAges 19 years+ - NCT06715969Enrolling by invitation
Comparing two treatments for low back pain
This study compares two different hands-on treatments for low back pain. It may be a good fit if you have ongoing back pain and haven't had recent therapy or medication.
Gaziantep, sehitkamilAges 35–60 - NCT06689826Enrolling by invitation
Core Strength in Rotator Cuff Injury
This study looks at whether core muscle strength (the muscles in your belly and lower back) is affected in people with a partially torn rotator cuff in one shoulder. If you join, you will help researchers understand this connection, which might lead to better recovery programs.
Kırşehir, CentreAges 18–65 - NCT06677216Enrolling by invitation
Botox for jaw muscle pain study
This study tests if Botox injections can reduce pain in the jaw muscles caused by a jaw joint disorder (TMD). If you have this type of pain and are interested in Botox treatment, you may be able to join.
Utrecht, UtrechtAges 18 years+ - NCT06636331Enrolling by invitation
Pain relief after hip surgery: comparing two numbing methods
This trial compares two ways to numb the hip and thigh area after a specific type of hip surgery (cephalomedullary nailing). One method uses a continuous nerve block above the hip bone, and the other uses a continuous epidural. The goal is to find which offers better pain control.
Denpasar, BaliAges 18–65 - NCT06619340Enrolling by invitationPhase 4
Exparrel block for knee replacement pain relief
This trial tests a special numbing injection called an EXPAREL IPSA block to see how well it controls pain after knee replacement surgery. It is for people with knee arthritis who are having their first knee replacement under spinal anesthesia.
Germantown, TennesseeAges 18 years+ - NCT06603714Enrolling by invitation
Soft tissue massage at different muscle lengths study
This trial tests how soft tissue mobilization affects muscles when stretched compared to relaxed. It may help improve flexibility or recovery in healthy people.
Izola, PrimorskaAges 18–25 - NCT06601413Enrolling by invitation
Nerve block for pain after laparoscopic hysterectomy
This study tests a special type of nerve block (called M-TAPA) to manage pain after a laparoscopic hysterectomy. It aims to see if this block provides better pain relief than standard care.
AnkaraAges 18–65 - NCT06587919Enrolling by invitation
Brain training for pain after trauma
This trial tests a brain-training technique called EEG-neurofeedback to help people with ongoing pain after a traumatic event. It aims to retrain overactive brain networks to reduce pain and distress.
OdenseAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06576570Enrolling by invitation
Improving surgeon ergonomics with AI analytics
This trial uses AI to analyze surgeon posture and movements during acute care surgeries, with the goal of improving ergonomics and reducing physical strain. It may help identify better surgical practices for both surgeons and patients.
Gainesville, FloridaAges 18–99 - NCT06575010Enrolling by invitationPhase 4
Comparing pain relief methods for rotator cuff repair surgery
This trial tests two different pain relief methods for people having rotator cuff repair surgery. The goal is to see which one works better for managing pain after surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06571006Enrolling by invitation
Music therapy for pain relief during spinal tap in babies
This study tests whether playing gentle music during a lumbar puncture (a spinal tap) can help lower a baby's pain. It's for newborn infants who need this procedure and have normal hearing.
ErzurumAges 1 month–1 month - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT06550323Enrolling by invitation
Virtual reality for pain during chest tube removal
This study tests if using virtual reality can reduce pain, anxiety, and discomfort when a chest tube is removed after heart bypass surgery. If you are between 18 and 65 and have a chest tube after coronary artery bypass surgery, you may be able to join.
ErzurumAges 18–65 - NCT06465992Enrolling by invitationPhase 4
Liposomal bupivacaine with dexamethasone for foot surgery pain relief
This trial tests whether adding dexamethasone to liposomal bupivacaine in a nerve block provides better pain relief after foot or ankle surgery. If you're having foot or ankle surgery and are willing to answer a few surveys, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06402149Enrolling by invitation
Comparing two ways to numb the arm for surgery
This trial tests two different methods for numbing the arm (infraclavicular block) before upper extremity surgery. It aims to find out which approach works better to block pain.
AnkaraAges 18 years+ - NCT06337513Enrolling by invitation
Back pain study for early arthritis diagnosis
This trial looks at people with low back pain to find early signs of a spine arthritis condition. It may help diagnose the condition sooner and guide better treatment.
Sønderborg, Southern DenmarkAges 18–48 - NCT06275191Enrolling by invitation
Testing non-opioid pain relief after tooth extraction
This trial tests whether alternative pain treatments can replace opioid painkillers after wisdom tooth or other tooth removal in teens and young adults. It aims to find safer ways to manage dental pain without relying on opioids.
Lexington, KentuckyAges 12–25 - NCT06228755Enrolling by invitation
Study on group integrative care for chronic pain
This study looks at how well group medical visits that combine different treatments (like mind-body approaches) work for people with chronic pain. It aims to make these visits more available and helpful.
Chapel Hill, North CarolinaAges 18 years+ - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT06141902Enrolling by invitation
Herbal tea for stem cell donor well-being
This study tests whether a special herbal tea (Jing Si Herbal Drink) can help people who donate stem cells feel better physically and emotionally. It is for healthy stem cell donors who are willing to drink the tea as part of the study.
Hualien CityAges 20–55
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.