Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07053566Enrolling by invitation
Back muscle strengthening for rotator cuff tendinopathy
This study tests whether strengthening a back muscle (latissimus dorsi) helps people with rotator cuff tendinopathy. You may be able to join if you have had shoulder pain for at least 3 months and meet certain medical criteria.
AnkaraAges 18–50 - NCT07028151Enrolling by invitation
Massage versus standard care for teeth grinding
This study tests whether a classical massage can help relieve jaw tension and other symptoms of teeth grinding (bruxism) in college students, compared to standard treatments. If you grind or clench your teeth and are between 18 and 27, this might be a non-invasive option to explore.
Bartın, AnkaraAges 18–27 - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT07006389Enrolling by invitation
Shock wave therapy for plantar fasciitis follow-up study
This study looks at how well shock wave therapy works for people with plantar fasciitis that hasn't improved with other treatments. If you've already had shock wave therapy 3 to 6 months ago, your experience could help doctors understand what makes the treatment effective.
IstanbulAges 18 years+ - NCT07003802Enrolling by invitation
Understanding back muscle control in disc injury
This study looks at how the brain controls back muscles in people with chronic disc injuries. It compares patients before surgery or physical therapy to healthy controls to better understand muscle function.
La Jolla, CaliforniaAges 18–60 - NCT06997016Enrolling by invitationPhase 4
Recovery program for living donor kidney transplant
This trial tests a special recovery program (ERAS) for people who get a kidney from a living donor. The program aims to help you heal faster and feel better after surgery.
Fort Worth, TexasAges 18 years+ - NCT06989866Enrolling by invitationPhase 3
Testing if numbing injections reduce pain pill use after nose surgery
This trial tests whether a numbing injection (regional anesthesia) during nose surgery can reduce the need for strong pain pills afterward. It's for people having their first nose surgery at specific military hospitals.
Portsmouth, VirginiaAges 18 years+ - NCT06977958Enrolling by invitation
Gluteal enhancement trial for non-active women
This trial tests a program called NASM OPT to see if it can improve hip appearance in women who haven't exercised for the last 6 months. It might help you if you're looking to reshape your hips safely.
Ferdows, South Khorasan ProvinceAges 20–45 - NCT06977919Enrolling by invitation
New exercise method for chest firmness and shape
This trial tests a new technique (called NASM OPT) to help improve the shape and firmness of your chest. It is for women who have not been exercising and who want to enhance their chest appearance without using surgery.
Zahedan, Sistan and BaluchestanAges 20–45 - NCT06965920Enrolling by invitation
Spinal pain and balance study using gentle chiropractic care
This study tests a gentle chiropractic technique called flexion distraction to see if it improves how well you move and balance while standing. It may help if you have spinal pain and can stand with mild to moderate pain.
West Palm Beach, FloridaAges 18–100 - NCT06957990Enrolling by invitation
Music therapy during hernia surgery to reduce pain medication
This study tests if listening to music therapy before and during hernia surgery can lower the need for strong painkillers (narcotics). It may help you manage pain with less medication.
Cincinnati, OhioAges 18 years+ - NCT06945263Enrolling by invitation
Comparing two freezing methods for pain after appendix removal
This study compares two ways of numbing the belly during laparoscopic appendix removal in children. It aims to find which method gives better pain relief after surgery.
Vancouver, British ColumbiaAges 4–18 - NCT06936800Enrolling by invitation
Pinaverium Bromide to Prevent Pain After Shock Wave Treatment
This trial tests if a drug called pinaverium bromide can help prevent pancreatitis and reduce pain after a procedure that uses shock waves to break up large gallstones in the pancreas. It may be an option for people with chronic pancreatitis and stones that are at least 5 mm wide.
Jinan, Wenhuaxi RoadAges 18–85 - NCT06926322Enrolling by invitation
Treating dead baby molars with special medicines
This study tests different medicines to treat dead (necrotic) baby molars in children. The goal is to safely clean the infection and save the tooth so it can stay until it falls out naturally.
CairoAges 4–8 - NCT06924268Enrolling by invitation
Art therapy for mood and symptoms in palliative care
This trial tests whether a single art therapy session can improve mood and reduce symptom burden for patients in a palliative care unit. It aims to see if creative expression can help you feel better emotionally and physically.
Halifax, Nova ScotiaAges 18 years+ - NCT06919640Enrolling by invitationPhase 1
Psilocybin and brain implant study
This trial tests whether psilocybin (the active ingredient in magic mushrooms) affects brain activity in people who already have a brain-sensing device implanted. It may help researchers understand how psilocybin works in the brain.
San Francisco, CaliforniaAges 21–75 - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT06911437Enrolling by invitation
Knee pain relief with Chinese formula and massage
This study tests if combining a Chinese herbal formula called Xiaoyu Zhitong with a gentle drainage massage can reduce knee pain and swelling. It may help people whose knee symptoms are worse in cold, damp weather.
BeijingAges 25–70 - NCT06886633Enrolling by invitation
Breathing exercise and cold pack for wound cleaning pain
This study tests whether a simple breathing exercise and a cold pack can help reduce pain and anxiety while a wound is being cleaned (called sharp debridement). If you are having a wound cleaned and feel anxious about it, this may be a way to feel more comfortable.
Gaziantep, GaziantepAges Any age - NCT06880484Enrolling by invitation
Far-infrared socks for diabetic nerve pain
This study tests whether special far-infrared socks can help relieve nerve pain and improve nerve function in people with diabetic nerve damage. If you have mild to moderate nerve pain and live in Kayseri, you may be able to join.
Talas, KayseriAges 19 years+ - NCT06859697Enrolling by invitation
Herbal medicine for obesity with spine or joint pain
This trial tests whether herbal medicine can safely help with pain and weight loss in people who have both obesity (BMI 25 or higher) and back or joint pain. It aims to see if the treatment works and is safe.
Seoul, Gangnam-GuAges 19–69 - NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70 - NCT06800846Enrolling by invitationPhase 4
Pain relief after knee replacement: injection methods compared
This study compares two ways to give pain medicine during knee replacement surgery: one is injected into the bone, the other around the joint. Researchers want to see which works better and may help you recover with less pain.
Khlong Luang, Changwat Pathum ThaniAges 50–80 - NCT06777381Enrolling by invitation
Pain after root canal treatment in lower molars
This study compares how much pain people feel after a single root canal treatment on a lower back molar. It may help find a way to reduce discomfort after the procedure.
CairoAges 25–45
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.