Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05424198Recruiting
A new device for neck pain treatment compared to the standard one
This study tests a new device that uses heat to treat neck pain that has lasted at least 3 months. It compares the new device to the standard one to see if it works better or is safer.
Farmington, UtahAges 18 years+ - NCT07865325Enrolling by invitation
Light therapy for knee pain in teenage girls
This study tests whether a special light treatment can reduce knee pain in teenage girls. If it works, it could offer a drug-free way to ease discomfort and help you move more comfortably.
AmmanAges 14–18 - NCT07859111RecruitingPhase 3
YJ001 spray for diabetic nerve pain in the feet
This trial tests a spray called YJ001 for pain in the feet caused by diabetic nerve damage. It aims to see if the spray can reduce pain better than a placebo, and may offer a new way to manage this type of pain.
Beijing, Haidian DistrictAges 18 years+ - NCT07863960Recruiting
Light therapy for pain after cesarean section
This study tests a painless light treatment (photobiomodulation) applied to the cesarean incision to see if it reduces pain after surgery. It might help you recover with less discomfort.
Tegucigalpa, Francisco Morazán DepartmentAges 18–45 - NCT07855367Recruiting
Knee pain relief study for osteoarthritis patients
This study compares two procedures that use extreme cold or heat to target the nerves around the knee, with the goal of reducing pain from knee osteoarthritis. It is specifically for people with advanced knee osteoarthritis who also have bladder cancer.
CairoAges 40 years+ - NCT07855445Recruiting
Nerve pain and MRI findings in lumbar spinal stenosis
This study looks at how nerve pain relates to MRI results in people with lumbar spinal stenosis, a condition where the spinal canal narrows and presses on nerves. It aims to better understand the link between symptoms and imaging, which could help improve care.
Istanbul, IstanbulAges 18 years+ - NCT06217029Recruiting
MRI Study of Neck Pain in Adults
This study uses MRI scans to look at how neck pain affects young and middle-aged adults. It helps doctors understand the condition better and may guide future treatments.
Xi'an, ShaanxiAges 18–50 - NCT02753335Recruiting
Rehabilitation for complex regional pain syndrome
This study tests a comprehensive rehabilitation program for adults with complex regional pain syndrome (CRPS), a chronic pain condition usually affecting one arm or leg. It looks at how the program affects pain and brain function, aiming to improve daily life.
TromsøAges 18–70 - NCT07855380Recruiting
Ultrasound-guided pain block for chronic pain after cancer surgery
This study tests a pain-relieving injection placed near the belly muscles using ultrasound guidance, to see if it helps reduce long-term pain after abdominal surgery for cancer. It may offer a new way to manage pain without strong painkillers.
CairoAges 18–65 - NCT07853664RecruitingPhase 2/Phase 3
Dexamethasone and diclofenac gel for facial surgery pain
This study tests a gel containing two pain and swelling medicines applied to the skin after facial surgery or facial injury repair. The goal is to see if it provides better pain relief and less swelling than usual care.
DhamarAges Any age - NCT07854041Recruiting
Release techniques for kneecap pain
This study tests two hands-on therapies to ease kneecap pain. It may help if your pain has lasted at least three months and gets worse with stairs, running, or sitting for a long time.
Lahore, Punjab ProvinceAges 15–40 - NCT06287788Recruiting
Mouth soreness trial for nasopharyngeal cancer patients
This trial tests a new way to map mouth and throat sores caused by radiation therapy. It focuses on pain when swallowing to guide treatment, which may help reduce discomfort during cancer treatment.
Guangzhou, GuangdongAges 18 years+ - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06336447Recruiting
Virtual reality and nerve block for chronic knee pain
This study tests whether using virtual reality (VR) before a standard heat-based nerve block (radiofrequency ablation) can improve relief of long-term knee pain caused by arthritis. If you qualify, you'll receive the RFA procedure and may be randomly assigned to also use VR.
Chicago, IllinoisAges 18 years+ - NCT05968313Recruiting
Brain scan study of pain feelings in teens who self-harm
This study uses brain activity during a task to understand how teens who self-harm react to pain and empathy. It may help researchers learn what brain differences are linked with non-suicidal self-injury and guide better support for teens.
Chengdu, SichuanAges 15–18 - NCT06361485RecruitingPhase 1
Umbilical cord injection for chronic low back pain
This study tests whether a special injection made from umbilical cord tissue is safe and can help with long-term low back pain. It is for adults who have not had recent back procedures or certain health problems.
Scottsdale, ArizonaAges 20 years+ - NCT06333353Recruiting
Can brain stimulation reduce endometriosis pain?
This study tests whether a gentle, non-invasive brain stimulation technique (repetitive transcranial magnetic stimulation, or rTMS) can reduce ongoing endometriosis-related pain. If you have persistent pelvic pain that hasn't improved with other treatments, this trial may offer a new option to explore.
Ottawa, OntarioAges 18–60 - NCT06084520Recruiting
Pain questionnaire study for opioid and non-opioid patients
This study tests two questionnaires for people with long-term pain. Researchers want to see if the tools work well for both those taking opioids and those who are not. Your answers can help improve pain care.
Uppsala, UpplandAges 18–75 - NCT07853170Recruiting
Comparing 3 vs 5-needle knee nerve blocks for arthritis pain
This study compares two ways of numbing the nerves around the knee to see which gives better pain relief and improves quality of life for people with knee osteoarthritis. It might help you decide if a nerve block is a good option for your knee pain.
Tanta, El-GharbiaAges 18 years+ - NCT07845071RecruitingPhase 3
Cebranopadol for acute pain after surgery or injury
This study tests an investigational medication called cebranopadol to see if it safely and effectively relieves acute (short-term) pain after surgery or from a muscle or bone injury. It may offer a new option for people who need relief from moderate to severe pain.
Phoenix, ArizonaAges 18–75 - NCT07846163Recruiting
Pain assessment for chronic low back pain
This study looks at how the brain and nervous system process pain in people with long-lasting low back pain. It uses safe measurements inside a shielded room to compare chronic pain patients with healthy people, which may help improve pain treatments.
Thessaloniki, Central MacedoniaAges 18–45 - NCT07846722Recruiting
Comparing two medicines to reduce pain medicine use after laparoscopic hysterectomy
This study compares two drugs, esmolol and dexmedetomidine, to see which one better reduces the need for strong painkillers after laparoscopic hysterectomy. It may help you manage pain with fewer opioids.
AthensAges 20–70 - NCT07844395Recruiting
Stress ball for pain and anxiety during breast biopsy
This study tests whether squeezing a small ball (stress ball) during a breast biopsy can help reduce pain, anxiety, and changes in heart rate and blood pressure. If you are having your first breast biopsy, you may be able to participate and help learn if this simple technique improves comfort.
KayseriAges 18 years+ - NCT07848126Recruiting
Foam rolling after knee replacement surgery
This study tests whether using a foam roller after knee replacement surgery helps reduce pain and improve movement. If you are having your first knee replacement, this may help you recover faster.
Izmir, BalçovaAges 40 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.