Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,135 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT04512755Recruiting
AIMS medical outcomes study for new or established patients
This is an observational study where the AIMS team collects information from patients during a first visit or ongoing care. It helps the clinic understand patients’ experiences and outcomes, but it does not test a new medicine.
Seattle, WashingtonAges Any age - NCT05667090Recruiting
High-dose vitamin D3 to ease chronic pain in dialysis patients
This study tests whether taking a very high dose of vitamin D3 can reduce moderate to severe chronic pain in people on hemodialysis. It may help by improving vitamin D-related pathways that could affect pain, but you must also meet specific health and testing requirements.
TaipeiAges 20 years+ - NCT05679167Recruiting
Digital training program for long-lasting low back pain
This trial tests an online (phone/tablet/computer) training program for people with low back pain lasting more than 3 months. It may help you learn exercises and self-management steps through digital instructions.
VänersborgAges 18–50 - NCT05767619Recruiting
Digital tool to guide care for chest pain calls
This trial tests a digital decision-support tool that helps emergency teams manage people who call for help because of chest pain. It may improve how safely and consistently chest pain is assessed and treated in the ambulance setting.
Kungsbacka, Region HallandAges 18 years+ - NCT04706195Recruiting
Person-centered online rehab for chronic pain on sick leave
This trial tests an early, personalized (person-centered) rehabilitation program delivered through eHealth to help people living with long-term non-cancer pain. It may help reduce pain impact and improve function while you are on sick leave from work.
GothenburgAges 18–65 - NCT05922007Recruiting
Study of chronic pain effects on daily life
This study looks at how long-lasting pain and its treatment affect quality of life and physical activity. It asks people to complete questionnaires to understand what changes over time.
Ostrava, Moravian-Silesian RegionAges 18–65 - NCT05873894Recruiting
Testing pain changes during brain surgery under anesthesia
This trial studies how pain levels change during planned brain surgery while you are fully asleep, using special brain-monitoring recordings. The goal is to better understand acute pain signals during general anesthesia, which may help anesthesiologists manage pain more effectively.
ValenciaAges 18 years+ - NCT04189965Recruiting
Study of long-term memory of pain in healthy adults
This study looks at how people remember pain over time. It enrolls healthy adults so researchers can better understand the long-term effects of painful experiences.
BronAges 18–50 - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT06083558Recruiting
Pain and nausea after gallbladder surgery
This study looks at pain and nausea in adults who had their first gallbladder surgery between 2016 and 2025. It uses a national registry to understand recovery and help improve care.
Sundsvall, XAges 18 years+ - NCT03862365Recruiting
Study genetics in people with nerve pain
This study looks at genetic differences in people being checked for a common type of nerve problem called distal symmetric polyneuropathy (nerve damage that usually affects the hands and feet). By understanding genetics, researchers hope to learn more about why neuropathic (nerve) pain happens and how it may differ between people.
BergenAges 18–70 - NCT06094660Recruiting
Nerve blocking for knee arthritis pain
This study tests two treatments for knee arthritis pain when knee replacement isn't an option: a nerve block using heat (radiofrequency ablation) or a chemical injection (phenol), compared to standard care. It aims to find a better way to reduce pain and improve daily function.
Hoorn, North HollandAges 35–90 - NCT05757609Recruiting
Brain stimulation therapy for chronic low back pain
This trial tests whether a non-invasive brain stimulation treatment can improve physiotherapy results for people with long-lasting low back pain. You may be asked to do questionnaires and follow a treatment plan, and some people may be able to reduce pain or improve function.
GenevaAges 18–65 - NCT07867808Enrolling by invitation
Magnetic therapy versus water therapy for chronic pelvic pain
This study compares two non-drug treatments—pulsed electromagnetic therapy and hydrotherapy (warm water therapy)—to see which one better relieves long-term pelvic pain in men. If you have chronic pelvic pain from non-bacterial prostatitis, this trial could help you find a new way to manage your symptoms.
AmmanAges 42–52 - NCT02346396Recruiting
At-home brain stimulation trial for long-lasting nerve pain
This study tests a device that delivers mild electrical stimulation to the brain from home to help reduce chronic nerve pain. It focuses on people whose pain has not improved enough despite stable pain medicines.
BronAges 18–80 - NCT04853732Recruiting
Pain research registry for chronic low back pain
This study is a research registry that collects information from people with chronic low back pain (and some people without chronic pain). It may help researchers better understand pain patterns and guide future treatments.
Fort Worth, TexasAges 21–79 - NCT07868484Recruiting
Pain relief after chest surgery: comparing two numbing injections
This study tests two different numbing injections given before chest surgery to see which one controls pain better and improves recovery. It may help reduce discomfort after the procedure.
Denpasar, BaliAges 18–65 - NCT07864896RecruitingPhase 3
Study of a new pain medicine after knee replacement surgery
This trial tests a new oral pain medicine called suzetrigine for people who have a knee replacement. It aims to see if it helps control pain after surgery better or with fewer side effects than usual care.
New York, New YorkAges 18–80 - NCT06767566RecruitingPhase 1
Ketamine for depression and pain after cesarean delivery
This study tests whether ketamine, a medicine given during cesarean delivery, can help prevent or reduce postpartum depression and pain. It aims to find the best dose for new mothers.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06209346Recruiting
Remote physical therapy for chronic pelvic pain from endometriosis
This trial tests if a physical therapy program done at home through video calls can help reduce chronic pelvic pain in people with endometriosis. If you have ongoing pelvic pain and have already had medical or surgical treatment, this study may offer a new way to manage your pain.
Alcalà de Henares, MadridAges 18–55 - NCT06221709Recruiting
Radiofrequency for hip arthritis pain: a clinical trial
This trial tests whether a treatment called continuous radiofrequency can reduce pain from hip arthritis. It is for people with moderate arthritis in one hip who have had pain for more than six months.
Brasília, Federal DistrictAges 18 years+ - NCT06237075Recruiting
Brain imaging and mild stimulation for nerve pain
This study uses brain imaging (fMRI) and a mild electrical stimulation (tDCS) to understand and potentially help nerve pain. You may be eligible if you have nerve pain or numbness from peripheral neuropathy or a stroke, and can avoid caffeine/alcohol before visits.
TaipeiAges 20–90 - NCT05424198Recruiting
A new device for neck pain treatment compared to the standard one
This study tests a new device that uses heat to treat neck pain that has lasted at least 3 months. It compares the new device to the standard one to see if it works better or is safer.
Farmington, UtahAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,135 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.