Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06957158Recruiting
How calcium levels affect pain after abdominal surgery
This study looks at whether calcium levels in your blood can affect how much pain you feel after abdominal surgery. It may help doctors manage pain better after surgery in the future.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06960317Recruiting
Numbing injection for IUD placement pain
This study tests whether a numbing injection (lidocaine) in the cervix can reduce pain during IUD placement. It's for women who have never had a vaginal birth and are getting their first IUD.
La Jolla, CaliforniaAges 18–50 - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years - NCT06965452Recruiting
Embolization for back pain from worn-out facet joints
This study tests if a minimally invasive procedure, called trans-arterial embolization, can reduce low back pain caused by aging facet joints (facet arthropathy). It may help people who haven't found relief from other treatments like injections or nerve blocks.
Manhasset, New YorkAges 18–85 - NCT06968689Recruiting
Brain activity study for experimental and chronic pain
This study uses MRI and EEG to look at brain connections involved in pain. It may help us understand how the brain processes pain and could lead to better treatments.
Houston, TexasAges 18–60 - NCT06970028Recruiting
Sensation study in ADPKD patients
This study looks at how people with ADPKD (a kidney condition that causes cysts) sense touch and temperature on their skin. It will compare their results with those of healthy volunteers to better understand the condition and help future treatments.
LeuvenAges 12 years+ - NCT06973122Recruiting
Nerve blocks for pain after abdominal surgery
This study tests two different nerve-block methods to reduce pain inside the belly after surgery. It compares a block near the stomach nerves to a block in the abdominal wall, to see which works better for controlling deep pain.
AlexandriaAges 20–50 - NCT06975761RecruitingPhase 2
Comparing two root canal fillings for pain
This study compares two types of root canal filling materials to see which one is better at reducing pain after the procedure. If you have a painful lower back tooth that needs a root canal and you are a healthy man aged 20-40, you may be able to join.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06978816Recruiting
Ear pressure points plus pain meds for kidney stone relief
This study tests whether pressing specific points on the ear, along with pain medicine, can relieve kidney stone pain faster than pain medicine alone. It's designed for people with confirmed kidney stones and moderate to severe pain who haven't taken pain relievers recently.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT06983678Recruiting
Quitting smoking and pain sensitivity study
This study looks at how quitting smoking affects pain sensitivity in people who smoke, especially those with chronic low back pain. Researchers will use brain scans and daily surveys to understand these changes.
Durham, North CarolinaAges 21–65 - NCT06984939Recruiting
Handheld distraction tool for kids during needle procedures
This study tests a small handheld tool that may help distract children and teenagers during painful procedures like getting an IV, a blood draw, a dental needle, or if you have just been diagnosed with type 1 diabetes and need frequent blood checks and insulin shots. The tool is meant to make the experience less stressful.
Bergen, VestlandAges 8–15 - NCT06985849Recruiting
Gentle exercise for chronic low back pain
This study compares two gentle exercise programs (Feldenkrais and Otago) to see which one helps people with chronic low back pain and balance problems feel better and move more easily. It focuses on adults who have had pain for at least 3 months and have some trouble with balance.
LahoreAges 18–65 - NCT06991075Recruiting
TENS for pain relief during IUD placement
This study tests if a small device called TENS (which uses mild electrical pulses) can reduce pain when getting an IUD placed. If you are coming to MUSC Women's Health for an IUD insertion and choose a specific type, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06991205Recruiting
Web mind-body program for pain and substance use
This trial tests a web-based mind-body program to help people who have ongoing arm or hand pain and also use substances like alcohol or cannabis. It aims to improve resilience and reduce pain without requiring in-person visits.
Boston, MassachusettsAges 18 years+ - NCT06993922Recruiting
Scalp block with added sedative for brain surgery pain
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
CairoAges 18–65 - NCT06996561RecruitingPhase 2/Phase 3
How your genes affect pain relief after surgery
This study looks at how your genes might affect pain relief from a medication called nalbuphine after abdominal or pelvic surgery. It aims to personalize pain management based on your genetic makeup.
Karachi, SindhAges 18–70 - NCT06999772Recruiting
Combining brain stimulation with physiotherapy for chronic back pain
This study tests if adding a non-invasive brain stimulation technique to physiotherapy can help veterans with chronic low back pain. It aims to improve pain and function by targeting both the brain and the body.
Québec, QuebecAges 18–65 - NCT07002541Recruiting
Nerve block comparison for breast surgery pain
This study tests two different nerve-block methods (PECS-II and ESP) to see which better reduces painkiller use during breast surgery. A special monitor guides how much pain medicine you need. The goal is to help you recover with less opioid side effects.
IstanbulAges 18–80 - NCT07002853Recruiting
Nature walks for chronic back pain in older adults
This trial tests whether spending time in nature can help older adults with long-term low back pain feel better and move more easily. If you are 65 or older and have had back pain for at least three months, you may be able to join.
Saguenay, QuebecAges 65 years+ - NCT07002944Recruiting
Testing nerve treatment for shoulder pain after mastectomy
This study compares two types of pulsed radiofrequency (a minimally invasive treatment using radio waves) to see which better relieves shoulder pain in women who have had a mastectomy. It's for women who still have pain despite taking a high dose of tramadol.
CairoAges 18–65 - NCT07003113Recruiting
Blood flow therapy for knee and back pain
This study tests a treatment called ischemic preconditioning, which uses a blood pressure cuff to temporarily restrict blood flow to your leg. It may help reduce pain from osteoarthritis in the knee or chronic back pain.
Chicago, IllinoisAges 50 years+ - NCT07004881Recruiting
Comparison of two hand-on knee treatments for kneecap pain
This trial compares two gentle physical therapy techniques (Mulligan and Maitland mobilization) to see which works better for kneecap pain. If you have had knee pain for at least 2 months and it hurts with stairs, sitting, or squatting, this study may help find the best treatment for you.
IslamabadAges 18–40 - NCT07006675RecruitingPhase 3
NSAIDs for Tibia Fracture Pain and Healing Study
This study tests whether NSAID pain relievers (like ibuprofen) affect bone healing after a broken tibia and if they can help reduce the need for stronger painkillers. If you qualify, you could help doctors learn the safest way to manage pain after this common injury.
Indianapolis, IndianaAges 18–80
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.