Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06910644Recruiting
Pain relief after mastectomy: dexmedetomidine vs lidocaine
This trial tests whether adding dexmedetomidine or lidocaine to anesthesia during mastectomy helps reduce long-term pain after surgery. It's for women with breast cancer undergoing mastectomy with lymph node removal.
CairoAges 18–75 - NCT06913270Recruiting
Virtual reality for pain during burn dressing changes
This study tests whether using virtual reality (VR) during dressing changes can help reduce pain and anxiety for adults with burn injuries. If you have moderate to severe pain during dressing changes, this approach might offer extra comfort without extra medication.
CairoAges 18–65 - NCT06915662RecruitingPhase 2
A nerve cap for pain after finger amputation
This trial tests a small nerve cap, called Tulavi Allay, placed on the end of a cut nerve during finger amputation surgery. The cap is meant to reduce pain and protect the nerve ending. It is for people who have lost one or more fingers in an accident.
Boston, MassachusettsAges 22 years+ - NCT06917300Recruiting
Virtual reality to reduce pain and anxiety before spine surgery
This trial tests if using virtual reality before surgery can help reduce pain and anxiety in people having elective spine surgery. If you're scheduled for spine surgery and speak Polish, you may be able to participate.
Lodz, Łódź VoivodeshipAges 25–70 - NCT06917651RecruitingPhase 3
Study of a new pain medicine for arm or leg injuries in the ER
This trial tests a fast-acting pain pill (sufentanil) placed under the tongue for people with moderate to severe pain from a single arm or leg injury. It aims to see if it works well in the emergency room.
FranceAges 18 years+ - NCT06918470Recruiting
Do noise cancelling headphones help with pain after surgery?
This study tests whether wearing noise cancelling headphones after gynecologic laparoscopy can reduce pain. If you are a woman having this surgery, you may be able to participate.
Wuhan, HubeiAges 18–55 - NCT06921174RecruitingPhase 2
Pelvic pain relief after childbirth: massage vs device
This study compares two non-surgical therapies for postpartum perineal pain: traditional perineal massage versus a small silicone device used inside the vagina. If you have persistent pain after a vaginal birth and have not tried other treatments yet, this trial may help you find relief.
Murcia, MurciaAges 18 years+ - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT06924671Recruiting
GLA:D Back Canada program for chronic low back pain
This study tests a program called GLA:D Back Canada, which is designed to help people with long-lasting low back pain. It focuses on exercises and education to improve your back health and daily function.
Edmonton, AlbertaAges 18 years+ - NCT06927531Recruiting
Pilates ball and massage for reducing labor pain
This study tests whether using a Pilates ball and sacral massage during labor can help reduce pain, shorten delivery time, and improve your birth experience. It is for first-time mothers with a full-term, low-risk pregnancy.
Şehitkamil, Gazi̇antepAges 18–35 - NCT06928597Recruiting
GPR therapy for chronic low back pain
This study tests a physical therapy method called Global Postural Re-education (GPR) for people with long-term low back pain that is not caused by a specific disease. It aims to see if GPR can help reduce pain and improve function.
Salvador, Estado de BahiaAges 18–55 - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT06932432Recruiting
Psychological support study for young adults with chronic pain
This study tests a new approach to psychological support for young adults (ages 18-25) with chronic pain that started in childhood. It uses daily surveys on your smartphone to adjust support based on what you need day to day.
Seattle, WashingtonAges 18–25 - NCT06932887RecruitingPhase 3
Walking to reduce arthritis pain
This study tests a walking program to help reduce pain from osteoarthritis. It is designed for people with arthritis in their hips, knees, feet, or spine.
Salt Lake City, UtahAges 45 years+ - NCT06933303Recruiting
Distraction for pain in children with burns
This trial tests if using a kaleidoscope can help distract children aged 7-12 from pain during burn dressing changes, in a setting where pain medicine is not usually given. The goal is to see if this simple tool can reduce pain without extra medication.
Empangeni, KwaZulu-NatalAges 7–12 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65 - NCT06938568Recruiting
Personalized back training for low back pain
This study tests a personalized back exercise program for people with long-lasting low back pain that limits their daily activities. The goal is to see if it helps improve physical function and reduce pain.
Lucerne, Canton of LucerneAges 18–65 - NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT06943898Recruiting
Core and Breathing Exercises for Chronic Low Back Pain
This study tests if core and breathing exercises can improve balance and body awareness in people with chronic low back pain. The exercises are gentle and focus on strengthening the muscles that support your spine.
Sivas, MerkezAges 18–65 - NCT06946290Recruiting
Nerve block for pain relief after heart surgery
This study tests a nerve block, called an intertransverse process block, to see if it helps people feel better and recover faster after heart surgery. The block is given during surgery to reduce pain.
Hong KongAges 18 years+ - NCT06947122Recruiting
Mindfulness app for opioid use and chronic pain
This trial tests a mindfulness-based app (Mindful Journey) to help people with both opioid use disorder and chronic pain. You'll use the app daily for a short time to see if it reduces pain and supports your recovery.
Phoenix, ArizonaAges 18 years+ - NCT06948162Recruiting
Testing dental MRI for routine dental care
This study explores whether a dental-dedicated MRI can be used for routine dental imaging. It may help improve dental care by providing detailed images without radiation.
Minneapolis, MinnesotaAges 18 years+ - NCT06955117Recruiting
McKenzie vs manual therapy for low back pain
This study compares two physical therapy methods to see which works better for low back pain that has lasted more than 4 weeks. It could help you find a more effective treatment without surgery or strong medication.
Malakand, KPKAges 35–45
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.