Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,142 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06939257Recruiting
Hormone therapy and pain in gender diverse adults
This study looks at how gender-affirming hormone therapy affects pain in gender diverse (GM) adults. It may help understand whether these hormones change how you feel pain.
Kansas City, KansasAges 18–50 - NCT06937853Recruiting
Genes and painkiller response for tooth pain
This trial tests whether your genes affect how well a common painkiller (NSAID) works for tooth pain after a root canal procedure. It may help find the best pain relief for you.
Erzurum, ErzurumAges 18–65 - NCT06932406Recruiting
Personality and self-help for jaw pain
This study tests whether a self-management program for jaw and face pain works differently in people with different personalities. You will learn techniques to manage your pain at home.
Valencia, ValenciaAges 18–65 - NCT06932887RecruitingPhase 3
Walking to reduce arthritis pain
This study tests a walking program to help reduce pain from osteoarthritis. It is designed for people with arthritis in their hips, knees, feet, or spine.
Salt Lake City, UtahAges 45 years+ - NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT06893822Recruiting
Griffonia simplicifolia for pain in healthy volunteers
This trial tests if a natural supplement called Griffonia simplicifolia can change how your body processes pain. It is looking for healthy people to take part.
GrazAges 18–99 - NCT06854809Recruiting
Cognitive therapy vs. exercises for chronic shoulder pain
This study compares two non-surgical treatments for long-lasting shoulder pain: a new approach called cognitive functional therapy that combines movement with education, versus standard exercises. If you have chronic shoulder pain and are looking for a drug-free option, this trial may help you find which treatment works better.
São Carlos, São PauloAges 18–65 - NCT06924671Recruiting
GLA:D Back Canada program for chronic low back pain
This study tests a program called GLA:D Back Canada, which is designed to help people with long-lasting low back pain. It focuses on exercises and education to improve your back health and daily function.
Edmonton, AlbertaAges 18 years+ - NCT06928597Recruiting
GPR therapy for chronic low back pain
This study tests a physical therapy method called Global Postural Re-education (GPR) for people with long-term low back pain that is not caused by a specific disease. It aims to see if GPR can help reduce pain and improve function.
Salvador, Estado de BahiaAges 18–55 - NCT06925152RecruitingPhase 4
Nerve block for C-section pain in complex surgery history
This study tests a targeted numbing injection (a nerve block) in the belly wall during C-sections to improve pain control and recovery for people who have had multiple or complex abdominal surgeries. It aims to see if this approach reduces the need for strong pain medicines.
Memphis, TennesseeAges 18–50 - NCT06917651RecruitingPhase 3
Study of a new pain medicine for arm or leg injuries in the ER
This trial tests a fast-acting pain pill (sufentanil) placed under the tongue for people with moderate to severe pain from a single arm or leg injury. It aims to see if it works well in the emergency room.
FranceAges 18 years+ - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT06915662RecruitingPhase 2
A nerve cap for pain after finger amputation
This trial tests a small nerve cap, called Tulavi Allay, placed on the end of a cut nerve during finger amputation surgery. The cap is meant to reduce pain and protect the nerve ending. It is for people who have lost one or more fingers in an accident.
Boston, MassachusettsAges 22 years+ - NCT06811103Recruiting
How chronic pain patients make decisions about treatment
This study looks at what helps people with chronic pain make choices about their treatment. You will be asked some questions during your first pain clinic visit to see how your decision-making relates to how well treatments work.
Paris, ParisAges 18 years+ - NCT06894355Recruiting
Hydrotherapy for athletes with long-term back pain
This trial tests whether group hydrotherapy (water-based exercise) can help athletes with long-term low back pain. It may be a good fit if you are an active athlete, have had back pain for at least 3 months, and train frequently.
NetanyaAges 18 years+ - NCT06910982Enrolling by invitation
Yoga and Mindfulness for Chronic Low Back Pain
This study tests whether a combination of yoga and mindfulness exercises can help reduce chronic lower back pain. It compares this program to usual care, and may be a good fit if your pain is bothersome but you are not too afraid that moving will make it worse.
Karachi, SindhAges 25–45 - NCT06910540Recruiting
Acu-TENS for pain and stress in IVF
This trial tests if acu-TENS, a needle-free acupressure device, can reduce pain and stress in women before and during an embryo transfer procedure. It's designed for women going through IVF treatment.
Hong KongAges 18 years+ - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT06902233Recruiting
Brain stimulation for chronic low back pain
This trial tests if a non-invasive brain stimulation technique can help people with long-lasting low back pain. It uses mild electrical currents to adjust brain activity and may reduce pain and improve daily function.
Dunedin, OtagoAges 18–75 - NCT06418217Recruiting
Exercise and education for lateral hip pain
This study tests whether exercise and patient education can help people with long-term lateral hip pain (pain on the outside of the hip). If you've had hip pain for over 6 months and an MRI confirms the cause, you may be able to join.
Horsens, HorsensAges 18–75 - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT06891625Recruiting
Movement performance in people with chronic back pain
This study looks at how people with long-term back pain move. It aims to understand movement patterns in chronic back pain, which could help design better treatments.
HuddingeAges 18 years+ - NCT06888895Recruiting
Stretching for tight hamstrings in low back pain
This study compares two types of hamstring stretching techniques (passive vs. active-passive) to see which one improves flexibility more in people with chronic low back pain. It may help you if your hamstrings feel tight and your pain has lasted at least 3 months.
Cébazat, FranceAges 18–65 - NCT06129890Recruiting
Brain stimulation for nerve pain and depression
This trial tests whether a noninvasive brain stimulation technique (rTMS) can help people with long-term nerve pain who also have depression. It aims to see if this treatment can reduce pain and improve mood.
Saint-EtienneAges 18–85
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,142 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.