Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07765095Recruiting
Nerve block for pain after hip socket surgery
This study tests a numbing injection around the hip socket to see if it reduces pain after surgery to fix a broken hip socket. It may help you feel better and need less pain medicine after your operation.
San JuanAges 18 years+ - NCT07766720Recruiting
Eggshell membrane and turmeric supplements for exercise recovery
This trial tests whether taking eggshell membrane, curcumin (turmeric), or both together can help your muscles recover faster after intense exercise. It may reduce soreness and help you bounce back sooner.
College Station, TexasAges 18–40 - NCT07378735Recruiting
Back to Life: early rehab after spinal fusion surgery
This trial tests an early rehabilitation program for people having lumbar spinal fusion surgery to see if it helps them get back to daily life faster. It may be a good option if you live in Copenhagen or Frederiksberg and have had low back pain for more than three months.
Glostrup MunicipalityAges 18 years+ - NCT07763158Recruiting
Treatment for severe knee pain using artery embolization
This study tests a procedure that blocks tiny arteries in the knee to reduce pain from severe arthritis. It is for people who cannot have knee replacement surgery because of other health issues.
Jeddah, Mecca RegionAges 18 years+ - NCT07423039Recruiting
Ear acupressure for anxiety and pain during breast cancer surgery
This study tests if pressing on specific points on the ear (acupressure) can help reduce anxiety and pain during breast cancer surgery. It compares acupressure plus standard care to standard care alone, and may be a drug-free way to help you feel calmer before and after your procedure.
StuttgartAges 18–99 - NCT06618820Enrolling by invitationPhase 3
Extended tranexamic acid after knee replacement
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
Germantown, TennesseeAges 18 years+ - NCT07578324Recruiting
TENS to reduce pain during prostate biopsy
This study tests whether TENS (a gentle electrical stimulation applied to the skin) can help reduce pain when combined with numbing medicine during a prostate biopsy procedure. The goal is to see if this may make the biopsy more comfortable for patients.
Gdansk, Pomeranian VoivodeshipAges 40 years+ - NCT04094701Recruiting
Study of opioid needs after hip arthroscopy surgery
This study looks at how much pain medicine (opioids) people actually need after hip arthroscopy and what factors may affect it. It may help improve safer, more personalized pain control after surgery.
Chicago, IllinoisAges 18–80 - NCT07559006Recruiting
Shoulder Pain After Stroke and Its Effects on Arm Function
This study looks at how shoulder pain affects arm movement, balance, and daily activities in people who've had a stroke. Researchers want to understand the connection between shoulder pain and physical recovery after stroke.
Kütahya, KütahyaAges 18–80 - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT07659015Enrolling by invitation
Using a hand exercise tool during IV placement
This study tests if using a simple hand-extension rubber band during IV placement can help reduce pain or improve the procedure. It may be an option for right-handed adults getting an IV in specific arm veins.
Konya, MeramAges 18–65 - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+ - NCT07485517Recruiting
Deep vs Moderate Muscle Block for Hysterectomy
This study compares two levels of muscle relaxation (deep versus moderate) during hysterectomy surgery to see which may be better for recovery. If you are a woman scheduled for a planned hysterectomy and are in generally good health, you might be eligible.
Menoufia, Eg.mnAges 18–60 - NCT07324499Recruiting
Dexamethasone with nerve block for shoulder surgery
This trial tests if adding dexamethasone to a standard numbing medicine (bupivacaine) affects how much of the medicine stays in your blood. It may help improve pain relief after shoulder surgery.
SantiagoAges 18–90 - NCT06691269Recruiting
Light therapy for pain-free dental care in kids
This study tests a special light therapy called photobiomodulation to see if it can reduce pain during routine dental care in children. It may offer a safe, non-drug way to help kids feel more comfortable at the dentist.
Baltimore, MarylandAges 6–12 - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT07434895RecruitingEarly Phase 1
Can CBD Change How You Use Cannabis?
This study looks at how taking CBD (a cannabis compound that doesn't get you high) affects your cannabis use. It is for healthy adults who use cannabis for recreational reasons, not for medical treatment.
Lexington, KentuckyAges 18–55 - NCT07756203Recruiting
Comparing two hand-held treatments for shoulder pain
This study tests two non-surgical treatments for shoulder pain caused by shoulder impingement. Both treatments use hand-held tools to ease pain and improve movement.
IstanbulAges 40–60 - NCT06717308Recruiting
Testing a gentler adhesive drape for wound therapy
This trial compares a special adhesive drape (the switchable one) with the standard drape during negative pressure wound therapy (a treatment that uses suction to help heal wounds after surgery). The goal is to see if the new drape causes less pain when removed.
Los Angeles, CaliforniaAges 18 years+ - NCT07730216Recruiting
Ultrasound-Guided Knee Block Study for Knee Replacement
This study looks at whether using ultrasound to guide a numbing injection around the knee can improve pain control after knee replacement surgery. It aims to make recovery more comfortable.
Konya, KonyaAges 18 years+ - NCT07756918Recruiting
Shockwave therapy versus dry needling for jumper's knee
This study compares two non-surgical treatments for jumper's knee (pain at the front of the knee from overuse): extracorporeal shockwave therapy (using sound waves to stimulate healing) and dry needling (using thin needles to release tension). The goal is to see which one works better for reducing pain. If you're eligible, you might get one of these treatments, and your progress will be followed to see how well it works.
Lahore, Punjab ProvinceAges 18–35 - NCT07318688RecruitingPhase 3
Testing HMI-115 for endometriosis pain
This trial tests an experimental drug called HMI-115 to see if it reduces pain from endometriosis. If you have moderate to severe period pain and non-period pain, and you have a surgical diagnosis, you may be able to join.
Beijing, Beijing MunicipalityAges 18–49 - NCT07587931Recruiting
Concentric vs Eccentric Exercise for Partial Rotator Cuff Tears
This study compares two types of shoulder exercises—one where you shorten the muscle and one where you lengthen it—to see which works better for partial tears of your rotator cuff (the muscles that stabilize your shoulder). The goal is to reduce pain and improve shoulder function.
Elâzığ, MErkezAges 18–65 - NCT07524049Recruiting
Giving Children a Voice in Pediatric Anesthesia
This study listens to what children, their families, and doctors think about anesthesia care (the medication that puts you to sleep during surgery). Researchers want to understand how to make the experience better and less scary for kids having procedures.
Aarau, Canton of AargauAges 6 years+
Hear when a new Pain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.