Clinical trials
Pancreatic cancer clinical trials
Cancer that begins in the tissues of the pancreas. We’re tracking 706 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07230509RecruitingPhase 2
Glue injection to prevent pancreatic leaks after Whipple surgery
This study tests injecting a medical glue into the pancreas during a Whipple procedure to see if it can prevent leaks. It may help people with a soft pancreas and small pancreatic duct.
Minya, Minya GovernorateAges 18–75 - NCT07132541RecruitingPhase 1
New surgical glue technique for pancreas connection after Whipple surgery
This trial tests a new method using a surgical glue called N-butyl-2-cyanoacrylate to seal the pancreas after a Whipple procedure. It may help prevent leaks and improve recovery for patients with a soft pancreas and small pancreatic duct.
Minya, Minya GovernorateAges 18–75 - NCT06843551RecruitingPhase 2
Testing a new immunotherapy combo for advanced pancreatic cancer
This trial is testing two immunotherapy drugs (balstilimab and botensilimab) to see if they can shrink tumors in people with advanced pancreatic cancer that has worsened after at least one prior treatment. If you have microsatellite stable (MSS) disease, you may be eligible.
Miami, FloridaAges 18 years+ - NCT05939063Recruiting
Testing two surgery approaches for early left pancreatic cancer
This trial compares two ways of doing surgery in people with early, left-sided pancreatic cancer that can be removed. It may help find the approach with better outcomes while aiming to keep the operation safe and effective.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06159478RecruitingPhase 2
Testing binimetinib for BRAF fusion brain tumors and pancreatic cancer
This trial tests a targeted drug, binimetinib, for people with low-grade glioma (a type of brain tumor) or pancreatic cancer that has a specific genetic change called a BRAF fusion. The drug aims to block signals that help these tumors grow.
Kashiwa, ChibaAges 12 years+ - NCT06391892RecruitingPhase 3
Liquid biopsy guided treatment for early pancreatic cancer
This trial uses a liquid biopsy (a simple blood test that looks for cancer DNA) to decide whether you should have chemotherapy before surgery or go straight to surgery. It is for people with pancreatic cancer that has not spread beyond the pancreas.
Linz, Upper AustriaAges 18–99 - NCT07250100Recruiting
Study of gut bacteria in pancreatic cancer and precancer
This study looks at the bacteria living in your gut and pancreas to understand how they might affect pancreatic cancer and precancerous changes. It is for people who are already scheduled for an endoscopic procedure to look at or treat a pancreatic lesion.
Herlev, Capital RegionAges 18 years+ - NCT06585072Recruiting
Pancreatic cancer and diabetes risk after surgery
This trial studies how pancreatic cancer affects blood sugar and the risk of developing diabetes after surgery. Patients who have their pancreas removed will provide blood and tissue samples to help understand this link.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06307080Recruiting
Combined ablation and immunotherapy for pancreatic cancer with liver spread
This study tests a new treatment combining tumor destruction with heat/cold (ablation) and an immunotherapy drug (PD-1) for people whose pancreatic cancer has spread to the liver. The goal is to help the immune system fight the cancer better.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06069297Recruiting
Prehabilitation before pancreatic cancer surgery
This trial tests whether a pre-surgery program of exercise and nutrition (called prehabilitation) can help people with pancreatic cancer recover better after surgery. Participants will receive guidance on physical activity and diet before their operation.
Milan, LombardyAges 18 years+ - NCT06249321RecruitingPhase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9
This trial tests a combination of chemotherapy (mFOLFIRINOX) and radiation therapy for people with advanced pancreatic cancer that has stopped responding to chemotherapy and whose CA19-9 tumor marker levels are normal. The goal is to see if this approach can help when standard treatments are no longer working.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06662006RecruitingPhase 2
Nal-IRI chemo with immunotherapy and radiation for pancreatic cancer
This trial tests a combination of chemotherapy (Nal-IRI, 5-FU, leucovorin), an immunotherapy drug (PD-L1 inhibitor), and a targeted anti-angiogenic pill, with or without radiation (SBRT), as a second-line treatment for people with metastatic pancreatic cancer that has progressed after first-line therapy.
Nanjing, JiangsuAges 18–75 - NCT03492671RecruitingPhase 2
Two chemotherapy drugs plus radiation before pancreatic surgery
This trial tests whether giving two already-approved chemotherapy drugs and radiation before surgery works better for localized pancreatic cancer. It’s meant for people whose cancer looks removable by surgery and who haven’t had prior pancreatic cancer treatment.
Loma Linda, CaliforniaAges 18 years+ - NCT06173310Recruiting
MRI-guided chemo before surgery for pancreatic cancer
This study tests whether using a special MRI scan to guide chemotherapy can help people with pancreatic cancer that is on the edge of being removable. The goal is to shrink the tumor enough for successful surgery.
Indianapolis, IndianaAges 19 years+ - NCT05764720Recruiting
Personalized targeted radiation for borderline pancreatic cancer
This study tests a personalized form of stereotactic radiation therapy (high-precision radiation planned to fit your tumor) after you’ve had some chemotherapy. It aims to treat pancreatic tumors while limiting exposure to nearby healthy organs.
Birmingham, AlabamaAges 18 years+ - NCT05195281Recruiting
Study changes in pancreatic cancer during treatment
This study follows how pancreatic cancer changes over time while you’re receiving treatment before surgery. It may help doctors understand how the cancer evolves and guide better future treatment choices.
MilanAges 18 years+ - NCT03937453Recruiting
Pancreatic cancer screening for people with new or worsening diabetes
This study checks whether regular imaging can find pancreatic cancer earlier in people who recently developed diabetes or whose diabetes is getting worse. It may help detect pancreatic problems sooner when treatment options are likely better.
New Haven, ConnecticutAges 50 years+ - NCT01174121RecruitingPhase 2
Immunotherapy made from your tumor-fighting immune cells
This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for certain metastatic cancers. It’s designed for people whose cancer has not responded to standard treatments and who can safely provide a small tumor sample for cell-making.
Bethesda, MarylandAges 18–72 - NCT06340620Recruiting
Comparing a new ultrasound tool to the standard scope
This study compares a new, possibly easier-to-use ultrasound tool (EndoSound Vision System) to the standard echoendoscope for looking at organs like the pancreas, bile duct, or lymph nodes. If you are already scheduled for an endoscopic ultrasound, you may be able to join.
Orlando, FloridaAges 18–100 - NCT05005403RecruitingPhase 1
Testing azirkitug for lung, head/neck, and other solid cancers
This Phase 1 study tests how a new medicine (azirkitug) behaves in the body and how safe it is, given by IV infusion alone or with other cancer drugs. It may help people with several advanced solid tumor cancers, especially after standard treatments have stopped working.
Duarte, CaliforniaAges 18 years+ - NCT05837767Recruiting
Radiation study for tumors that spread to soft tissue areas
This study looks at how a planned form of palliative radiation therapy treats certain solid cancers that have spread outside the brain to larger soft-tissue areas. It may help shrink tumors and relieve symptoms, but it also asks you to meet specific safety and treatment-timing rules.
Basking Ridge, New JerseyAges 18 years+ - NCT06454448RecruitingPhase 1/Phase 2
Adebrelimab plus chemotherapy for advanced pancreatic cancer
This trial tests a combination of a targeted immune therapy (Adebrelimab) with three chemotherapy drugs for people with metastatic pancreatic cancer who haven't had any treatment yet. The goal is to see if this combination can shrink tumors and help people live longer.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT03556228RecruitingPhase 1/Phase 2
Tested medicine for tumors with TrkA changes, alone or with pembrolizumab
This early-phase study tests VMD-928, a targeted cancer medicine, for cancers that have TrkA-related tumor changes. It may be given by itself or with pembrolizumab to see if it can shrink tumors when standard treatments have not worked.
Santa Rosa, CaliforniaAges 18–80 - NCT05365581RecruitingPhase 1
Study drug for stomach and pancreatic cancers with lab-checked targets
This Phase 1 trial tests ASP2138 alone or with other cancer medicines in adults with stomach (including GEJ) or pancreatic cancer. You may be eligible if your tumor has a specific protein marker and your health tests and scan results meet safety requirements.
Orange, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for pancreatic cancer?
- Yes. Clin2 currently lists 706 recruiting pancreatic cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pancreatic cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pancreatic cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.