Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05854524Recruiting
Exercise program to protect the brain in Parkinson’s disease
This trial studies whether doing regular moderate aerobic exercise can help protect the brain in people with Parkinson’s disease. It also includes people without Parkinson’s to compare exercise effects, using fitness and safety screening to keep everyone safe.
Las Vegas, NevadaAges 30–85 - NCT07725562RecruitingPhase 2/Phase 3
VG081821AC tablets for early to mid-stage Parkinson's disease
This trial tests a new oral medication, VG081821AC, in people with early to mid-stage Parkinson's disease. The goal is to see if it can improve movement symptoms and slow the progression of the condition, and it may offer a new treatment option for those not yet on levodopa.
BeijingAges 18–80 - NCT07710625Recruiting
Heat sensitivity scale for Parkinson's disease
This study is testing a new questionnaire to measure how heat affects people with Parkinson's disease. If you have Parkinson's and notice changes with heat, this may help doctors better understand your symptoms.
Istanbul, TurkeyAges 40–85 - NCT07682532Recruiting
Theanine and Mediterranean diet for Parkinson's symptoms
This trial tests whether a supplement called L-theanine and a Mediterranean diet can improve sleep, digestion, and inflammation in early-stage Parkinson's disease. It may help if you are in stage 1 and live with a healthy partner.
IstanbulAges 50–80 - NCT06167681RecruitingPhase 1/Phase 2
Cell Therapy NouvNeu001 for Parkinson's Disease
This trial tests a new cell therapy called NouvNeu001 for Parkinson's disease. It involves a one-time brain surgery to deliver the treatment, and researchers will check if it's safe and helps with symptoms.
Beijing, Beijing MunicipalityAges 50–75 - NCT06710574RecruitingPhase 4
Probiotics for sleep problems in Parkinson's disease
This study tests whether taking probiotics can improve REM sleep behavior disorder (RBD) in people with Parkinson's disease. You will receive either a probiotic supplement or a placebo, and researchers will use brain scans to see how it affects your symptoms.
BeijingAges 40–85 - NCT06629389RecruitingPhase 2
Cannabidiol (Kanbis) for Parkinson's symptoms
This trial tests whether cannabidiol (CBD) can help with Parkinson's disease symptoms. Researchers want to see if it's safe and effective for people with mild to moderate Parkinson's who are already on stable medications.
Mendoza, Mendoza ProvinceAges 40–80 - NCT07572071RecruitingPhase 1
Cell transplant study for moderate Parkinson's disease
This trial tests whether transplanting specially grown cells (DopaCell) into the brain can safely help people with moderate Parkinson's disease whose symptoms aren't well controlled by medication. The cells are intended to produce dopamine, the chemical that Parkinson's affects.
ShirazAges 30–70 - NCT07543861RecruitingPhase 1
Standing Balance Training Study for Parkinson's Disease
This study tests a new way to help people with Parkinson's disease improve their balance and standing ability through guided exercises in a lab setting. Researchers want to see if this approach can safely help reduce balance problems and fall risk.
Ann Arbor, MichiganAges 50 years+ - NCT07518290Recruiting
Home brain stimulation for Parkinson's disease movement symptoms
This trial tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (TTIS) that you can use at home with remote supervision. It aims to improve movement problems like stiffness, tremor, and slowness in people with mild-to-moderate Parkinson's disease.
Shanghai, Shanghai MunicipalityAges 40–80 - NCT07488377Recruiting
Cognitive Self-Confidence in Parkinson's Disease
This study tests a new questionnaire to measure how confident people with Parkinson's feel about their thinking and memory. It may help doctors better understand and support cognitive changes in Parkinson's.
Istanbul, TurkeyAges 40–85 - NCT07465107Recruiting
Motor and cognitive exercise in Parkinson's
This study tests whether combining motor (physical movement) exercises with cognitive (thinking) exercises can help people with Parkinson's disease. It may improve both movement and thinking skills.
Copenhagen NVAges 18 years+ - NCT07427498Recruiting
How beliefs affect hallucinations in Parkinson's disease
This study looks at how your past experiences and expectations might influence visual hallucinations if you have Parkinson's disease. It involves cognitive tests and compares people with and without hallucinations, as well as healthy volunteers.
GrenobleAges 18–85 - NCT07424924Recruiting
Walking, activity, and sleep study for Parkinson's
This study looks at how walking, daily activity, and sleep are connected in Parkinson's disease. It compares people with Parkinson's to healthy volunteers to understand these links better.
IstanbulAges 40–75 - NCT07404241Recruiting
Brain activity linked to movement and mood swings in Parkinson's
This study looks at brain signals related to motor and psychiatric changes in people with Parkinson's who are scheduled for deep brain stimulation (DBS) surgery. The goal is to better understand why symptoms fluctuate and how DBS may help.
GenevaAges 18–80 - NCT07271927Recruiting
Light therapy for Parkinson's motor and thinking changes
This study tests whether shining light on the whole body (photobiomodulation) can help with movement and thinking problems in Parkinson's disease. It is for people in early to moderate stages who can walk independently.
Yangsan, Gyeongsangnam-doAges 40 years+ - NCT07277205Recruiting
Balance and thinking exercises for Parkinson's disease
This study compares two types of rehabilitation exercises for people with Parkinson's disease: one focusing on balance (vestibular) and one combining balance with thinking tasks (dual-task). It aims to see which is better at improving balance and daily function. If you are between 40 and 75, have mild to moderate Parkinson's, and can do cognitive tasks, you might be eligible.
Istanbul, MaltepeAges 40–75 - NCT06916260Recruiting
Light therapy study for people with Parkinson's disease
This study tests whether light therapy can help people with Parkinson's disease. Participants will receive light therapy sessions and have their symptoms checked before, after, and three months later.
Newark, DelawareAges 50–80 - NCT07213856Recruiting
Dietary help for constipation in Parkinson's disease
This study tests whether a special diet can help improve constipation symptoms in people with early-stage Parkinson's disease. It aims to see if changing what you eat can make bowel movements more regular and comfortable.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07166757RecruitingPhase 1/Phase 2
Study of XS411 for early-onset Parkinson's disease
This trial tests a new treatment called XS411 for people with early-onset Parkinson's disease (age 50 or younger at diagnosis). It is for those whose motor symptoms are not well controlled with standard medications and who may benefit from a neurosurgical procedure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07157735RecruitingPhase 2
Testing an anti-inflammatory drug for early Parkinson's disease
This trial tests whether the anti-inflammatory drug dapansutrile can help people with early Parkinson's disease. You would get either dapansutrile or a placebo (a pill with no active drug) to see if it slows the disease.
CambridgeAges 50–80 - NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT07110376Recruiting
Brain recordings during sleep with deep brain stimulation for Parkinson's
This study looks at brain activity during sleep in people with Parkinson's who have a deep brain stimulation (DBS) device. It aims to understand how different DBS settings affect sleep, which may help improve treatment.
Cleveland, OhioAges 18 years+ - NCT07102342RecruitingPhase 1/Phase 2
Cell therapy for Parkinson's disease
This trial tests a new cell treatment for Parkinson's disease. It involves injecting special cells into the brain to see if they can safely replace damaged cells and improve symptoms. It might help people who have had Parkinson's for several years and still respond well to medication.
New York, New YorkAges 30–75
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 315 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.