Clinical trials
Parkinson's Disease and Parkinsonism clinical trials
Below are recruiting parkinson's disease and parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06197698Recruiting
Parkinson's and gut-brain connection study
This study is looking at how the bacteria in your gut might affect your brain in Parkinson's disease. It involves two types of brain scans to see differences between people with Parkinson's and healthy volunteers.
DouliuAges 20 years+ - NCT04607174Recruiting
Test knee muscle activation in people with nerve or movement disorders
This study checks how well your knee muscles “turn on” during guided, controlled knee movements. It may help researchers understand movement problems and improve testing or therapies for neuromotor (nerve/movement) disorders.
Milan, MIAges 18–70 - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07640542RecruitingEarly Phase 1
Brain imaging study for Parkinson's and MSA patients
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Tübingen, Baden-WurttembergAges 50–75 - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT05995782RecruitingPhase 1
Testing safety of FB418 in healthy people
This trial studies a new drug called FB418 to see if it's safe and how the body handles it. It first tests single doses in younger healthy men, then multiple doses, and also includes an optional group for healthy older adults.
SeoulAges 19 years+ - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT07519096Recruiting
Home-Based Fall Prevention Program for Parkinson's Disease
This study tests a fall prevention program designed for people with Parkinson's disease and their care partners. It aims to help reduce falls and improve balance and safety at home.
Beachwood, OhioAges 18 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT06481540Recruiting
Smartphone app for cough training in Parkinson's
This trial tests a smartphone app called SpiroGym to help people with Parkinson's disease improve their cough strength. It aims to see if app-guided exercises can make coughing more effective for clearing the airway.
PragueAges 40–80 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT07400731Recruiting
Ear stimulation for Parkinson's symptoms
This study tests whether a device that stimulates the ear can improve Parkinson's symptoms during 'off' periods, when medication wears off. It compares how you feel before and after ear stimulation.
IstanbulAges 44 years+ - NCT07382674Recruiting
Exercise program for older adults with Parkinson's
This trial tests a fun exercise system designed for older adults with mild to moderate Parkinson's disease. It aims to help improve movement and well-being through engaging physical activities.
Atlanta, GeorgiaAges 40 years+ - NCT07384143Recruiting
Robotic arm rehab for cognitive recovery after stroke
This study tests whether robot-assisted arm exercises can help people recover both arm movement and thinking skills. It may be an option if you have arm weakness after a stroke or other neurological condition.
Messina, MaineAges 18–75 - NCT07355842Recruiting
Can slow brain waves slow Parkinson's?
This study tests whether playing soft sounds during deep sleep can slow down brain changes in people with REM sleep behavior disorder (a condition linked to Parkinson's disease). It is for people who have this sleep disorder or were recently diagnosed with Parkinson's, and are not yet on Parkinson's medications.
Zurich, Canton of ZurichAges Any age - NCT07360886Recruiting
Early detection of brain conditions in active drivers
This study looks at how well doctors can spot early signs of certain brain conditions in people who drive. You may join if you have a valid license, are between 18 and 85, and have one of the neurological diagnoses the study is focusing on.
Olomouc, Olomouc RegionAges 18–85 - NCT06296810Recruiting
Smart brain stimulation for Parkinson's during exercise
This study tests if a smart brain stimulator (deep brain stimulation, or DBS) can adjust itself during exercise to help people with Parkinson's disease move better. The goal is to improve how well the device works while you're active.
Aurora, ColoradoAges 20–70 - NCT07291687Recruiting
Test of tDCS for improving walking
This study tests whether a safe, non-invasive brain stimulation (tDCS) can improve movement and walking in people who have trouble with motor function. You can join if you're able to walk daily, with or without a walking aid, and don't have metal in your brain.
Toronto, OntarioAges Any age - NCT07284290RecruitingPhase 4
Brain imaging, thinking, and medication study for Lewy body dementia
This study looks at how brain changes affect attention and thinking in people with Lewy body dementia. It includes brain scans, an EEG, and a medication option to see if it helps with symptoms.
Richmond, VirginiaAges 50–89 - NCT07257861Recruiting
Apomorphine Pump for Late-Stage Parkinson's at End of Life
This trial studies whether a continuous apomorphine pump can help people with advanced Parkinson's disease who can no longer take oral medications and are receiving palliative care. The pump delivers medicine under the skin to manage symptoms when other treatments are no longer possible.
CrestAges 18 years+ - NCT07219927Recruiting
Patient experiences with pump-delivered Parkinson's drug
This study looks at real-world experiences of people with Parkinson's who are using ONAPGO, a medication given continuously under the skin through a pump. The goal is to understand how this treatment works in daily life.
Aliso Viejo, CaliforniaAges 18 years+ - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+
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Common questions
- Are there clinical trials for parkinson's disease and parkinsonism?
- Yes. Clin2 currently lists 723 recruiting parkinson's disease and parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson's disease and parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson's disease and parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.