Clinical trials · Minneapolis–St. Paul, MN
Parkinson’s disease clinical trials in Minneapolis–St. Paul
We’re tracking 21 recruiting parkinson’s disease studies with a site in or near Minneapolis–St. Paul — including Early Phase 1, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Minneapolis–St. Paul
- NCT07226284Recruiting
Testing a nerve stimulation device for leg movement in Parkinson's
This study tests if a device that stimulates the vagus nerve (a nerve in your neck) can improve leg muscle activity and walking balance in people with Parkinson's disease. You would participate in experiments while wearing the device to see how it affects your movement.
Minneapolis, MinnesotaAges 21–76 - NCT06405334Recruiting
Study on balance problems in Parkinson's disease
This study looks at how Parkinson's disease affects balance and the brain signals involved. It aims to understand why some people with Parkinson's have trouble with balance, and in part of the study, it will look at how deep brain stimulation (a device that sends electrical impulses to the brain) affects balance.
Minneapolis, MinnesotaAges 18 years+ - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT06998303Recruiting
Brain imaging study for Parkinson's DBS patients
This study uses MRI scans to look at brain activity in people with Parkinson's disease who have a Medtronic Percept DBS device. The goal is to better understand how deep brain stimulation works.
Minneapolis, MinnesotaAges 21 years+ - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Minneapolis, MinnesotaAges 18 years+ - NCT06506058Recruiting
Study on balance and brain in Parkinson's freezing of gait
This study looks at how the balance system and brain work together to cause freezing of gait in Parkinson's disease. By understanding these factors, researchers hope to find better ways to help people walk more steadily.
Minneapolis, MinnesotaAges 21–80 - NCT06848205Recruiting
Brain pacemaker study for freezing of gait in Parkinson's
This study looks at how a special brain pacemaker (called the Medtronic Percept device) affects walking problems like freezing of gait in people with Parkinson's. It aims to help understand and improve treatment.
Minneapolis, MinnesotaAges 21–75 - NCT04373317RecruitingPhase 4
Comparing two medicines for hallucinations in Parkinson's disease
This study compares two drugs, pimavanserin and quetiapine, to see which works better for hallucinations or delusions caused by Parkinson's disease. The goal is to help patients manage these symptoms more effectively.
Minneapolis, MinnesotaAges 40 years+ - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05934747Recruiting
Parkinson’s trial for people with implanted brain stimulators
This study tests an approach to improving Parkinson’s symptoms in people who already have deep brain stimulation (DBS) devices. It focuses on patients who are able to do walking tests safely and confirm they can understand and consent.
Minneapolis, MinnesotaAges 18–85 - NCT05656586Recruiting
At-home testing for Parkinson’s patients with a DBS device
This study checks how well people can do specific at-home movement tasks using their Medtronic Percept deep brain stimulation (DBS) system. It may help improve how DBS settings are tested and monitored outside the clinic, which could make care safer and more personalized.
Minneapolis, MinnesotaAges Any age - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT06692920Recruiting
Parkinson's brain signals study during DBS surgery
This study looks at brain signals in people with Parkinson's who are already scheduled for Deep Brain Stimulation (DBS) surgery. The goal is to better understand how certain brain pathways work, which could lead to improved treatments.
Minneapolis, MinnesotaAges 21–75 - NCT03021031Enrolling by invitation
Deep brain stimulation for Parkinson’s patients
This trial studies a type of brain stimulation to help reduce symptoms in people with Parkinson’s disease. You may be able to join if you have Parkinson’s and are being considered for this treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT06464029Recruiting
Balance and walking study in Parkinson's disease
This study looks at balance problems in people with Parkinson's disease. It uses simple tests to understand what causes trouble with standing and walking, which may help find better treatments.
Minneapolis, MinnesotaAges 45–80 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT03623672Enrolling by invitation
Study for early signs of Parkinson-related brain changes
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Minneapolis, MinnesotaAges 18 years+ - NCT04994015RecruitingTeam says not enrolling
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Golden Valley, MinnesotaAges 18 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Golden Valley, MinnesotaAges 40–80 - NCT06999330Enrolling by invitation
TMS for anxiety in Parkinson's disease
This study tests whether transcranial magnetic stimulation (TMS), a non-invasive brain treatment, can help reduce anxiety in people with Parkinson's disease. You may qualify if you have both Parkinson's and significant anxiety symptoms.
Saint Paul, MinnesotaAges 40–90
Hear when a new Parkinson’s disease trial opens near Minneapolis–St. Paul, MN
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Parkinson’s disease trials in other cities
Where these studies are running near Minneapolis–St. Paul
Institutions with a site for the recruiting parkinson’s disease studies listed above.
- University of Minnesota · 16 studies
- Minneapolis VA Health Care System · 2 studies
- Struthers Parkinson's Center - HealthPartners Park Nicollet · 2 studies
- HealthPartners Neuroscience Center
What taking part in a parkinson’s disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting parkinson’s disease studies in Minnesota.
Common questions
- Are there parkinson’s disease clinical trials near Minneapolis–St. Paul?
- Yes. We're currently tracking 21 recruiting parkinson’s disease studies with a site near Minneapolis–St. Paul, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a parkinson’s disease study near Minneapolis–St. Paul?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minneapolis–St. Paul to take part?
- Not necessarily. These studies have a site near Minneapolis–St. Paul, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New parkinson’s disease studies open near Minneapolis–St. Paul regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.