Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 739 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05908266Recruiting
Training control for reaching in Parkinson disease
This study tests a way to help people control reaching movements during a task. You may be able to join if you can understand the instructions and successfully perform the reaching task during the experiment.
Louvain-la-NeuveAges 18–99 - NCT05962489Recruiting
Sleep-focused DBS therapy study for Parkinson’s disease
This study looks at a sleep-focused approach to brain stimulation (DBS) in people with Parkinson’s disease. You may be able to join if you’re planning or scheduled for specific DBS surgery at the University of Minnesota and have the needed brain imaging.
Minneapolis, MinnesotaAges 21 years+ - NCT05997043RecruitingEarly Phase 1
Botulinum toxin for overactive bladder in Parkinson's disease
This trial tests if botulinum toxin A injections can help control overactive bladder symptoms in people with Parkinson's disease who haven't gotten enough relief from standard bladder medications. It aims to see if the treatment is safe and effective.
Guangzhou, GuangdongAges 25–80 - NCT05998772Recruiting
How sugar affects Parkinsons symptoms
This study looks at how sugar levels might change the way Parkinsons disease feels. If you have mild to moderate Parkinsons, you may be able to join and help researchers learn more about the role of food in your symptoms.
KielAges 50–80 - NCT06113640RecruitingPhase 2/Phase 3
Montelukast for Parkinson's disease
This study tests if montelukast, an asthma medicine, can help people with Parkinson's disease. It is for adults who are already taking levodopa and want to see if adding this drug improves their symptoms.
Al MansurahAges 18–70 - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT06203106Recruiting
NYSCF Scientific Discovery Biobank
This study collects blood, saliva, or skin samples from people with certain neurological conditions and from healthy volunteers to help researchers better understand and find treatments for these diseases.
New York, New YorkAges 4 weeks+ - NCT07695233Recruiting
Ultrasound brain stimulation for freezing of gait in Parkinson's
This trial tests a noninvasive ultrasound treatment targeting a brain area called the pedunculopontine nucleus to help reduce freezing of gait (a sudden inability to walk) in Parkinson's disease. If you have Parkinson's and experience freezing, you may be eligible to try this new approach.
Toronto, OntarioAges 18–90 - NCT06508801Recruiting
Blood flow restriction to improve balance in Parkinson's
This study tests whether gently restricting blood flow to your legs during exercise can help improve balance for people with Parkinson's disease. You will do simple leg exercises while wearing a special cuff, which may strengthen muscles and improve steadiness.
San Antonio, TexasAges 40–85 - NCT06582121Recruiting
Sleep disorders in early and advanced Parkinson's disease
This study looks at sleep problems in people with Parkinson's disease, people with REM sleep behavior disorder (a condition that causes acting out dreams), and healthy volunteers. The goal is to understand how sleep is affected in early and full Parkinson's disease.
Clermont-FerrandAges 18 years+ - NCT06588439Recruiting
Cognitive-motor training for Parkinson's
This study tests a type of training that combines thinking tasks with movement exercises to see if it can improve symptoms in people with Parkinson's disease.
TaipeiAges 40–80 - NCT06602544Recruiting
Robotic suit to prevent freezing in Parkinson's
This study tests a robotic suit designed to help prevent freezing of gait (a sudden feeling of being stuck) in people with Parkinson's disease. You'll attend 8 visits to see if the suit can improve your walking and reduce falls.
Allston, MassachusettsAges 18–90 - NCT06640673Recruiting
Brain Wave Study for Mild Memory Problems and Parkinson's Disease
This study uses a special brain wave test (high-density EEG) to learn more about mild memory problems and how they might be linked to Parkinson's disease. If you join, you'll help researchers understand brain activity patterns that could lead to better diagnosis and care.
Lido, ItalyAges 50–90 - NCT06679374RecruitingPhase 2
Can varenicline help reduce falls in Parkinson disease?
This phase 2 trial tests a medicine called varenicline (brand name Chantix) to see if it can reduce falls in people with Parkinson disease who also have a specific brain change (loss of a chemical called acetylcholine in the back of the brain) and mild cognitive problems. The study will help determine if this medicine is safe and effective for this group.
Ann Arbor, MichiganAges 45 years+ - NCT06680830RecruitingPhase 2
Testing NEU-411 for early Parkinson's with LRRK2 gene change
This trial tests an experimental drug called NEU-411 for people with early Parkinson's disease who have a specific genetic change (LRRK2). It aims to see if the drug can slow the disease progression.
Sun City, ArizonaAges 40–80 - NCT06705517Recruiting
Mediterranean diet study for Parkinson's disease
This trial tests whether a Mediterranean diet can help people with Parkinson's disease. You would either follow your usual diet or switch to a Mediterranean diet for six months and provide blood and stool samples.
Varese, VareseAges 40–85 - NCT07685873Recruiting
MAO-B PET imaging in Parkinson's and related diseases
This study uses a special type of brain scan (PET/CT) to look at a protein called MAO-B in people with Parkinson's disease or related conditions. The scan may help doctors understand more about the disease and could be part of your regular care.
Hefei, AnhuiAges 18–90 - NCT06730074Recruiting
Robotic exercise for Parkinson's motor and thinking skills
This study tests a new robotic system that combines movement and mental exercises for people with Parkinson's. It may help improve both your physical and thinking skills.
Ofakim, SouthAges 50–75 - NCT06785298RecruitingPhase 2/Phase 3
Fexofenadine as add-on treatment for Parkinson's disease
This trial tests whether adding fexofenadine, a common allergy medicine, to your current Parkinson's treatment can help improve symptoms. It's for people aged 50 or older who are already on dopamine replacement therapy.
TantaAges 50–70 - NCT06846658Recruiting
Finding early signs of Parkinson's and related diseases
This study looks at cells from the nose, blood, and urine to find early markers for Parkinson's disease, similar conditions, and memory problems linked to Lewy bodies. If you have one of these conditions, joining could help improve early diagnosis.
Sesto Fiorentino, FIAges Any age - NCT06852352Recruiting
Modified brain lymph surgery for Alzheimer's or Parkinson's
This study tests a new, less invasive surgery to improve lymph drainage from the brain. It may help clear harmful proteins linked to Alzheimer's or Parkinson's disease.
Hangzhou, ZhejiangAges 50–80 - NCT06856941Recruiting
Walking exercise study for Parkinson's mobility
This trial tests whether a new type of walking exercise (called CsDCS) can help improve your ability to move around and do daily activities. It is designed for people with Parkinson's who are already on medication and can walk independently.
Recife, PernambucoAges 40 years+ - NCT06859528Recruiting
Walking program for people with Parkinson's disease
This study tests a community-based walking program designed for people with Parkinson's disease. It aims to see if regular walking can help improve movement and overall well-being.
St Louis, MissouriAges 30–85 - NCT06869135Recruiting
Saliva testing for brain diseases
This trial is collecting saliva samples from people with Alzheimer's, Parkinson's, or other brain diseases to find new ways to diagnose them. It may help improve early detection.
Florence, FIAges 45 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 739 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.