Clinical trials
Pathophysiology clinical trials
Below are recruiting pathophysiology clinical trials, each written for real people, not researchers. We’re tracking 52 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04776642Recruiting
Biobank for heart rhythm disorders and conduction problems
This study builds a biobank (a secure collection of medical information and body samples) for people with certain heart rhythm problems. You may be able to contribute to research that helps improve understanding and treatment of these conditions.
AmsterdamAges 18 years+ - NCT07770126Recruiting
Stomach bacteria study for gastric conditions and precancer
This study looks for certain stomach bacteria (other than the common H. pylori) that might be linked to stomach diseases or early signs of cancer. If you have a stomach condition, your participation could help doctors understand these bacteria better.
EdegemAges 18 years+ - NCT03287193Recruiting
Study genes behind rare, genetic-looking illnesses
This study is trying to find the gene or body-process cause of rare diseases (or rare forms of common diseases) when the reason is not yet understood. If you qualify, you may be asked to give genetic and health information that could help doctors diagnose and understand the condition better.
DijonAges Any age - NCT03541525Recruiting
Study on red blood cell-related diseases in families
This study looks at how red blood cells work in people who have a related condition—or who have family members with one. It may help researchers understand causes of these diseases and improve future care.
CotonouAges Any age - NCT06079567Recruiting
Study of FSHD2 progression over 18 months
This study follows people with FSHD2 over 18 months to learn how the disease progresses and affects daily life. No new drugs are tested—just regular check-ups and an MRI scan.
LeuvenAges 18–75 - NCT07156422Recruiting
Study of sensitive scalp in women without skin disease
This study is for women who have a sensitive scalp — feeling itchy, burning, or uncomfortable — but no scalp disease like psoriasis. Researchers want to understand what causes this sensitivity so they can help people like you.
BrestAges 18 years+ - NCT06320158Recruiting
Understanding muscle loss and obesity in older adults
This study looks at the link between muscle loss (sarcopenia) and obesity in older adults. It aims to understand why some older people who are overweight or obese also lose muscle strength and function, and how this affects recovery after hip surgery.
MilanAges 65–99 - NCT06208904Enrolling by invitation
Gut hormone’s role in post-meal blood pressure drops
This study tests whether a gut hormone called GIP is involved in causing blood pressure drops after eating. It may help find better treatments for people who feel dizzy or faint after meals.
Copenhagen, HellerupAges 18–85 - NCT06234761Recruiting
Study on immune responses in nasal polyps
This trial looks at how the immune system reacts in people with nasal polyps. It may help doctors better understand and treat this condition.
GhentAges 18 years+ - NCT06935825Recruiting
Breathing muscles in severe lung disease
This study looks at how the breathing muscles work in people with very advanced COPD who are waiting for a lung transplant. It aims to understand the problems these muscles face and how that affects patients.
AmsterdamAges Any age - NCT03422614Recruiting
Study immune-system disorders in people with primary immune problems
This study looks at what is happening in the immune system for people with an inherited (primary) immune problem. It may help researchers better understand the disease and how it works.
ZurichAges Any age - NCT03510442Recruiting
Study of joint illness patterns and genes in juvenile and adult diseases
This study follows people with systemic juvenile idiopathic arthritis (sJIA), adult-onset Still’s disease (AOSD), and similar conditions to learn how the illness works over time. It also collects blood and family information to study genetics and explain what causes flare-ups, which may help future care.
Bethesda, MarylandAges 1 day–100 years - NCT03773003Recruiting
Study of fatigue caused by cancer or chronic fatigue
This study looks at why fatigue happens in people with cancer and, in some cases, in people with chronic fatigue conditions. It may help researchers better understand the causes of fatigue so future treatments can be improved.
Homburg, SaarlandAges 18–80 - NCT03981276Recruiting
Study aims to understand inherited walking stiffness disorders
This study looks at the causes and biology (“biomarkers”) of hereditary spastic paraplegias and related conditions. You may join as someone with the condition, a family member without symptoms, or a healthy person, to help researchers understand what’s happening in the nervous system.
InnsbruckAges Any age - NCT03998852RecruitingPhase 3
PET study of brain chemical changes in stroke apathy
This Phase 3 trial uses special brain scans (PET) to understand what brain chemical systems are involved in apathy after stroke. Your results may help researchers better understand the cause of apathy and guide future treatments.
BordeauxAges 18–75 - NCT04354649RecruitingPhase 2
Test triage and treatment for immune-related arthritis from immunotherapy
This trial studies how doctors assess and manage immune-related arthritis or joint pain that happens after PD-1/PD-L1 cancer immunotherapy (sometimes with CTLA-4). It may help people get faster, more targeted care while monitoring safety.
Edmonton, AlbertaAges 18 years+ - NCT04421846Recruiting
Studying the causes of severe seizures and immune brain swelling
This study looks at what causes severe seizure episodes (“status epilepticus”) and a related immune condition that affects the brain (“dysimmune encephalitis”). The goal is to better understand the disease process, which may guide future care.
ParisAges 2 years+ - NCT04717388Recruiting
Study brain and feelings in people with tinnitus
This study looks at how tinnitus affects the brain, thinking, and emotional well-being. It compares people with chronic tinnitus to people without tinnitus (including a group related to a specific type of epilepsy surgery).
ParisAges 18 years+ - NCT05122962Recruiting
MRI study of heart rhythm and exercise capacity after congenital surgery
This study looks at how blood flow and heart rhythm may affect exercise ability in people born with certain heart defects that have been repaired or treated. It uses a specialized heart MRI and ultrasound measurements to better understand these problems and their causes.
Rochester, MinnesotaAges 18 years+ - NCT05202210Recruiting
Biobank study for people with Noonan syndrome
This study collects biological samples to better understand what causes Noonan syndrome. If you qualify, your participation could help researchers learn how the condition works and guide future care.
ToulouseAges 18–99 - NCT05216770RecruitingEarly Phase 1
Brain-scan study of voice dystonia and tremor
This early study uses brain and voice-related testing to better understand what is happening in the brain in people with laryngeal dystonia or voice tremor. The results may help scientists learn more about these conditions and how they differ from healthy voices.
Boston, MassachusettsAges 18–80 - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT05663840Recruiting
Exercise program study for focal neck dystonia
This trial tests how a structured exercise program affects the brain and body changes behind focal cervical dystonia (a movement disorder that causes abnormal neck postures). It may help people who are still having symptoms despite best-available treatments like botulinum toxin injections or medicines.
Gainesville, FloridaAges 30–85 - NCT05859191Recruiting
Study of immune cell markers in people with lupus
This study looks at how certain immune cells (natural killer T cells) behave in people with systemic lupus, by measuring specific immune receptor markers in blood. It may help researchers better understand lupus and how it can connect with other conditions like antiphospholipid syndrome or Sjögren’s.
ToursAges 18 years+
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Common questions
- Are there clinical trials for pathophysiology?
- Yes. Clin2 currently lists 52 recruiting pathophysiology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pathophysiology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pathophysiology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.