Clinical trials
Pathophysiology clinical trials
Below are recruiting pathophysiology clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05989763Recruiting
Constipation study for people with systemic sclerosis
This study looks at why people with systemic sclerosis (a disease that can affect connective tissues) develop constipation. It will use special tests to measure how well the colon moves waste, and it may help doctors find better treatments.
Houston, TexasAges 18 years+ - NCT06068114Recruiting
Stomach function study in people with diabetes
This study looks at how diabetes affects stomach function by measuring stomach activity with special tests. It may help doctors better understand and treat stomach problems in people with diabetes.
OstravaAges 18–70 - NCT06111950Recruiting
Study of RNU4ATAC and RTTN gene conditions
This study looks at rare genetic syndromes caused by changes in the RNU4ATAC or RTTN genes. It aims to understand how these changes affect the body by studying patients, their parents, and fetal tissue.
BordeauxAges Any age - NCT06253754Recruiting
Study of headache after spinal tap
This trial looks at why some people get a headache after a spinal tap and how treatment might help. It may be an option if you are between 20 and 40 and have this kind of headache.
Umeå, Västerbotten CountyAges 20–40 - NCT06302933Recruiting
Negative HIV test in children treated early: a study
This study looks at why some HIV-positive children who started treatment early may have a negative HIV antibody test. It uses stored blood samples from children who were in the Pediacam III study to better understand the immune response.
DoualaAges Any age - NCT06420141Recruiting
Nerve pain after ankle fracture surgery
This study looks at why some people develop nerve pain (neuropathic pain) after breaking their ankle and having surgery. If you have an ankle fracture that needs surgery, you may be able to join and help researchers understand this type of pain better.
Indianapolis, IndianaAges 18–85 - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06435585Recruiting
Heart failure genetics and response study
This study looks at how genes affect heart failure treatment response. It uses blood samples to find new markers that may help predict who will benefit most from therapy.
StockholmAges 18 years+ - NCT06439173Recruiting
Study on bone marrow recovery after CAR-T therapy
This study is looking at why some people develop low blood cell counts after CAR-T therapy for a type of lymphoma. It aims to find ways to help the bone marrow recover and work better.
SalamancaAges 18 years+ - NCT06471374Recruiting
Circadian rhythm in delayed sleep-wake phase disorder
This study looks at how your body's internal clock works in people with delayed sleep-wake phase disorder, especially those living at high altitudes. It aims to understand the causes of this sleep problem and may help find better treatments.
Boulder, ColoradoAges 16–40 - NCT06593041Recruiting
Platelets in lupus and other autoimmune diseases
This study looks at how platelets (small blood cells that help with clotting) might play a role in autoimmune diseases like lupus. By understanding this, researchers hope to find new ways to treat these conditions.
Strasbourg, FranceAges 18–70 - NCT06692920Recruiting
Parkinson's brain signals study during DBS surgery
This study looks at brain signals in people with Parkinson's who are already scheduled for Deep Brain Stimulation (DBS) surgery. The goal is to better understand how certain brain pathways work, which could lead to improved treatments.
Minneapolis, MinnesotaAges 21–75 - NCT06797661Recruiting
Brain lesion blood flow study before surgery
This study looks at how blood flow in the brain changes when there is a mass that can be removed with surgery. You would join before any treatment, which helps doctors understand the link between the brain lesion and blood vessel function.
BrusselsAges 18–90 - NCT06840860Recruiting
EPIC study: testing for VMPX
This study tests people for VMPX to learn more about the condition and to understand how it affects the body. You can join if you are willing to be tested and can give permission.
Kinshasa, MasinaAges Any age - NCT06968442Recruiting
Obesity and severe COVID-19 study
This study looks at how obesity affects the body's response to severe COVID-19. It compares people with obesity to healthy-weight healthcare workers to understand differences in the immune system.
Rotterdam, South HollandAges 18–65 - NCT07052539Recruiting
Kidney disease in heart failure with obesity
This study looks at how kidney disease relates to a type of heart failure (called HFpEF) that often happens in people with obesity. It will help doctors understand this connection better.
Jackson, MississippiAges 18–75 - NCT07081880Recruiting
Understanding SAPHO syndrome: genetics and immune response
This study looks at the causes of SAPHO syndrome—a rare condition that affects the skin, bones, and joints. Researchers want to understand how genes and the immune system play a role, which may help improve future treatments.
ParisAges 18 years+ - NCT07100782RecruitingPhase 3
Estrogen & pain trial for endometriosis pelvic pain
This study tests whether a drug called relugolix CT can reduce pelvic pain from endometriosis. You'll have brain scans and pain tests to measure how your body processes pain. It might help if other treatments haven't worked well.
Ann Arbor, MichiganAges 18–49 - NCT07175051RecruitingPhase 2
Testing a kidney-protecting drug in sickle cell disease
This study tests whether empagliflozin, a medicine that protects the kidneys in people with diabetes, can also protect the kidneys in people with sickle cell disease. The goal is to see if it can reduce protein in the urine, which is a sign of kidney stress.
Chicago, IllinoisAges 18–60 - NCT06490770Recruiting
Understanding knee pain and function
This study looks at how your knee joint works when you have pain or limited function. It uses MRI and electrical stimulation to learn more about cartilage and meniscus damage, which might help improve future treatments.
BolognaAges 18–60 - NCT07260942Recruiting
Study of ferroptosis in lupus
This study looks at whether a type of cell death called ferroptosis plays a role in lupus. Participants with lupus or with rheumatoid arthritis or inflammatory bowel disease will be compared to understand more about how lupus works.
BordeauxAges 18 years+ - NCT07395076Recruiting
Study of immune causes of acute respiratory distress
This trial looks at how the immune system might cause severe breathing problems (ARDS). It may help doctors understand what happens in the lungs during this condition and find better ways to treat it.
ParisAges 18 years+ - NCT03280888Recruiting
Blood cells and chronic myelomonocytic leukemia study
This research study examines blood cells from patients with chronic myelomonocytic leukemia (CMML), a rare blood cancer, to better understand how the disease develops and progresses. By studying your blood cells, researchers hope to learn more about what causes CMML and how to treat it better.
NiceAges 18 years+ - NCT07556497Recruiting
Blood cells and inflammation in diabetic heart disease
This study looks at why people with type 2 diabetes develop heart problems. Researchers will examine special cells in your blood and inflammation markers to better understand these complications.
DohaAges 18 years+
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Common questions
- Are there clinical trials for pathophysiology?
- Yes. Clin2 currently lists 51 recruiting pathophysiology studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pathophysiology trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pathophysiology trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.