Clinical trials
Patient clinical trials
Below are recruiting patient clinical trials, each written for real people, not researchers. We’re tracking 14,165 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05684510Recruiting
Clear aligners vs braces for mild overbite in adults
This trial compares clear plastic aligners with fixed braces to improve mild overbite (Class II) in adults who have not had orthodontics before. It may help you understand which option works better for your bite and alignment while also checking fit and dental health needs.
Hama, Hama GovernorateAges 15–20 - NCT05700617RecruitingEarly Phase 1
Testing cardiac pumping strength in cardiogenic shock
This early study looks at how well the heart is pumping in people with cardiogenic shock, using measurements taken during a right-heart catheter (a small pressure-monitoring test). It may help doctors better assess heart function and guide next-step treatments like LVAD, heart transplant, or valve surgery.
Chicago, IllinoisAges 18 years+ - NCT05674643Recruiting
Gastric testing during children’s surgery
This trial studies how the stomach is working in children around the time of surgery. It may help improve how doctors assess and manage stomach function to make surgery safer and more comfortable.
Boston, MassachusettsAges 2–18 - NCT05679349Recruiting
Help your clinic improve lung cancer screening for smokers
This study helps primary care clinics reach people who have a long smoking history so they can get lung cancer screening at the right time. It may help you (and others) get reminders and outreach to make screening easier to schedule.
Philadelphia, PennsylvaniaAges 50–77 - NCT05676827Enrolling by invitation
Study pain and stress in people with long-term jaw muscle pain
This trial looks at how long-lasting jaw (masticatory) muscle pain relates to the nervous system and emotional stress. It may help researchers understand why symptoms persist and guide future treatments.
WroclawAges 18–80 - NCT05681702RecruitingPhase 4
Personalizing medicines to reduce bleeding after stent procedure
This trial studies ways to reduce bleeding in people after a stent procedure (PCI) who have been taking two anti-platelet medicines (aspirin plus prasugrel or ticagrelor) for a set amount of time. It may help find a safer plan for preventing blood clots while lowering bleeding risk.
Jacksonville, FloridaAges 18 years+ - NCT05702853RecruitingPhase 1/Phase 2
CAR T-cell therapy after CD34 selection for CD19 lymphoma or CLL
This Phase 1/2 study tests a customized type of immune cell treatment (CD19 CAR T-cells) for people with certain relapsed or hard-to-treat lymphomas or CLL/SLL. It aims to improve control of disease by targeting the CD19 marker on cancer cells.
Charleston, South CarolinaAges 18 years+ - NCT05674825RecruitingPhase 1/Phase 2
Personalized treatment using tumor test results for aggressive cancers
This early-phase study tests whether a personalized cancer treatment plan based on your tumor’s test results can help people with aggressive cancers that are hard to treat. It may be an option if standard treatments didn’t work, aren’t possible for you, or you have few treatment choices.
Milwaukee, WisconsinAges 18 years+ - NCT05677802Recruiting
Stress-reduction program for newly diagnosed triple-negative breast cancer
This study tests whether a structured stress-reduction program can help people with newly diagnosed triple-negative breast cancer (stages I–III). The goal is to see if the program is practical and beneficial for patients during treatment.
Cleveland, OhioAges 18 years+ - NCT05705492RecruitingPhase 2
Olanzapine to help cancer-related weight and appetite loss
This Phase 2 trial tests whether olanzapine can help people with advanced cancer who are losing weight and not eating enough. It looks for improvements in appetite and weight while you receive your first-line palliative cancer treatment.
Portland, OregonAges 18 years+ - NCT05704283RecruitingEarly Phase 1
3D ultrasound to check lymph nodes in breast cancer
This early-phase study tests a 3D ultrasound scan to see lymph nodes in people being evaluated for breast cancer. It may help doctors better image lymph nodes during routine care.
Rochester, MinnesotaAges 18 years+ - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT05704647RecruitingPhase 2
Nivolumab plus relatlimab for melanoma in the brain
This Phase 2 study tests whether nivolumab plus relatlimab can shrink or control melanoma that has spread to the brain. It may help by boosting the immune system to attack the cancer, including melanoma in brain areas that can’t be treated with prior focused radiation.
Houston, TexasAges 18 years+ - NCT05676450Recruiting
Test blood DNA to find lymphoma changes and leftover disease
This study checks a blood test that looks for small DNA fragments (“cell-free DNA”) to find cancer changes that could guide treatment in diffuse large B-cell lymphoma. It also looks for “minimal residual disease,” meaning tiny amounts of lymphoma that may remain after treatment, and whether this test works across community cancer centers in Texas.
Houston, TexasAges 18 years+ - NCT05688579Enrolling by invitationPhase 4
Testing an aldosterone-blocking medicine in hard-to-control hypertension
This trial studies whether a medicine that blocks aldosterone (called an MRA) can improve cardiovascular outcomes in people with high aldosterone levels and high blood pressure. You may be asked to take the study medicine and have blood pressure, heart, and lab tests monitored over time.
Ürümqi, XinjiangAges 30–75 - NCT05675722RecruitingPhase 1
Vaginal reconstruction implant test for women born without a vagina
This Phase 1 study tests a vaginal implant/reconstruction device for people born with a missing or closed-off vagina. The goal is to check safety and how well the implanted vaginal tissue construct works over follow-up visits.
Winston-Salem, North CarolinaAges 15–45 - NCT05708508RecruitingPhase 3
Immune-guided vs universal medicine to prevent CMV after kidney transplant
This study compares two strategies to prevent a viral infection called CMV after kidney transplant. It tests whether an “immune-guided” approach (using your immune test results) can prevent CMV as well as or better than giving preventive antiviral medicine to everyone.
RouenAges 18–75 - NCT05698524RecruitingPhase 1
Temodar plus an investigational pill for recurrent brain cancer
This Phase 1 study tests an investigational drug (PCI-24781) together with Temodar in people whose high-grade glioma (grade III/IV) has come back after prior treatment. It aims to find a safe dose and see how well the combination may work for recurrent disease.
Omaha, NebraskaAges 19 years+ - NCT05681780RecruitingPhase 1
CD40L-treated immune cells for advanced lung cancer with certain gene changes
This Phase 1 study tests a lab-made immune cell treatment (TIL) boosted with CD40L, plus nivolumab, for stage IV or returning non-small cell lung cancer with specific gene changes (EGFR, ALK, ROS1, or HER2). It aims to help your immune system attack the cancer after it has grown despite standard treatments.
Tampa, FloridaAges 18 years+ - NCT05684562Recruiting
Lung function and exercise capacity in Fontan patients
This study looks at how well the lungs and heart work together during exercise in people who have had the Fontan operation. The goal is to understand how lung function affects overall fitness, which can help improve care for Fontan patients.
AnkaraAges 8–55 - NCT05708352RecruitingPhase 2
Ketogenic diet vs usual diet guidance for newly diagnosed glioblastoma
This trial tests whether a very low-carb, high-fat ketogenic diet helps people with newly diagnosed glioblastoma when combined with standard cancer treatment. You would compare this special diet guidance to the usual anti-cancer diet guidance while receiving the same standard-of-care treatments.
Los Angeles, CaliforniaAges 18 years+ - NCT05692388Recruiting
Study social needs support for Black adults with kidney and diabetes
This study looks at health-related social needs—like barriers to food, housing, or care—in African American adults living with type 2 diabetes and chronic kidney disease. It uses a mixed-methods approach to understand needs better and what support may help.
Milwaukee, WisconsinAges 18 years+ - NCT05702749Recruiting
Vestibular physical therapy before treatment for acoustic tumors
This trial tests whether physical therapy focused on balance and dizziness before surgery or targeted radiation (SRS) can improve how people with vestibular schwannoma (an acoustic tumor) feel and function. It aims to help prepare your balance system before treatment begins.
Milwaukee, WisconsinAges 18 years+ - NCT05705804Recruiting
Comparing statins and ezetimibe for heart patients with metabolic syndrome
This trial tests if pitavastatin alone or with ezetimibe affects blood sugar differently than atorvastatin in people who have heart or blood vessel disease and metabolic syndrome but do not have diabetes.
SeoulAges Any age
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Common questions
- Are there clinical trials for patient?
- Yes. Clin2 currently lists 14,165 recruiting patient studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patient trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patient trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.