Clinical trials · Philadelphia, PA
Pediatrics clinical trials in Philadelphia
We’re tracking 112 recruiting pediatrics studies with a site in or near Philadelphia — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT03067181RecruitingPhase 3
Active surveillance and chemotherapy for germ cell tumors
This study looks at how to manage germ cell tumors in children and young adults using careful monitoring for some patients and chemotherapy for others. It aims to see whether these approaches can control the cancer while avoiding unnecessary treatment when possible.
Philadelphia, PennsylvaniaAges Any age - NCT05634369RecruitingPhase 1/Phase 2
NK cell and chemotherapy trial for relapsed soft tissue sarcoma
This early-phase trial studies a type of immune cell treatment (NK cells) made from donor cells, given with chemotherapy drugs gemcitabine and docetaxel. It’s for children and young adults whose bone or soft tissue sarcoma has come back or hasn’t responded to prior treatment.
Philadelphia, PennsylvaniaAges 2–40 - NCT05839379Recruiting
Targeted therapy study for children and young adults with brain tumors
This trial studies a targeted medicine approach for high-grade glioma (a fast-growing brain tumor) and some diffuse midline tumors, including DIPG. It may help by matching treatment to tumor biology using tumor testing done before or around starting standard therapy.
Philadelphia, PennsylvaniaAges 1–39 - NCT05096481RecruitingPhase 2
Vaccine for brain tumors in children and young adults
This trial tests a vaccine that may help the immune system fight brain tumors (medulloblastoma, high-grade glioma, and DIPG). It is for patients who have already had standard treatment and whose tumors are still present or have returned.
Philadelphia, PennsylvaniaAges 3–39 - NCT05835310RecruitingPhase 3
IV anifrolumab for active lupus in children
This study tests whether an intravenous medicine called anifrolumab can safely improve active systemic lupus (SLE) in children. If you qualify, you may receive the study treatment and be closely monitored for safety and lupus symptoms.
Philadelphia, PennsylvaniaAges 5–17 - NCT03684018RecruitingPhase 4
Testing two doses of Privigen for children with CIDP
This study tests whether two different dose levels of Privigen (a type of immune blood treatment) are safe and effective for children and teens with CIDP. It may help improve nerve-related symptoms in people whose CIDP has been confirmed or is being evaluated as likely.
Philadelphia, PennsylvaniaAges 2–17 - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Philadelphia, PennsylvaniaAges 6 months–17 years - NCT00674388Recruiting
Improving care for children during anesthesia
This study aims to improve how anesthesia care is delivered to children in participating hospitals. Because it includes all children having anesthesia, it may help ensure safer, better care during procedures.
Philadelphia, PennsylvaniaAges Up to 21 years - NCT07778823Recruiting
Augmented reality support for CPR in children
This study tests whether augmented reality (a headset that projects images) can guide nurses and technicians during CPR on children. You may be asked to perform chest compressions while using this technology to see if it helps improve performance.
Philadelphia, PennsylvaniaAges 18 years+ - NCT01696721Recruiting
Pediatric radiation therapy registry for children under 22
This study is a registry that collects information from children and teens who receive radiation therapy at participating hospitals. It helps researchers learn how radiation is used in pediatrics and may improve future care.
Philadelphia, PennsylvaniaAges Up to 21 years - NCT02418442Recruiting
Kid rheumatic disease registry study for follow-up care
This is an observational study that follows children and teens with rheumatic (joint/inflammatory) diseases to better understand how they develop and are cared for over time. You may help by letting the study contact your family in the future and by completing study tasks as needed.
Philadelphia, PennsylvaniaAges Up to 21 years - NCT05711667RecruitingPhase 3
Letermovir to prevent CMV after stem cell transplant in kids
This trial tests whether the medicine letermovir can prevent a common virus (CMV) from coming back after an allogeneic stem cell transplant in children. It may help lower the risk of CMV infection during the vulnerable period right after transplant.
Philadelphia, PennsylvaniaAges 2–18 - NCT07494045RecruitingPhase 2
Study of CTAP101 for kids with chronic kidney disease
This study tests a new extended-release capsule (CTAP101) for children aged 8 to under 18 with moderate to severe chronic kidney disease (CKD). The goal is to see how the drug works in the body, if it's safe, and if it can help control mineral and hormone levels that are often out of balance in CKD.
Philadelphia, PennsylvaniaAges 1 month–17 years - NCT04485559RecruitingPhase 1
Trametinib and everolimus for recurrent gliomas
This trial tests two drugs, trametinib and everolimus, for children and young adults with recurrent or progressive gliomas (a type of brain tumor). The goal is to see if this drug combination is safe and effective in treating these tumors.
Philadelphia, PennsylvaniaAges 1–25 - NCT04914507Recruiting
Tracking long-term results of spine tethering in growing teens
This study follows kids who have a surgery called anterior vertebral body tethering (AVBT) for growing-related, idiopathic scoliosis. It looks at how well the curve stays corrected over time and how the spine grows, which may help improve future care decisions.
Philadelphia, PennsylvaniaAges Up to 18 years - NCT02493478Recruiting
Improve safety during placing breathing tubes in children
This trial looks at ways to improve the safety and quality of emergency breathing tube placement in pediatric critical care and emergency settings. It may help reduce complications and improve how clinicians do these urgent procedures.
Philadelphia, PennsylvaniaAges Any age - NCT07517133RecruitingPhase 3
Mitapivat for Children With Non-Transfusion-Dependent Thalassemia
This study tests a medicine called mitapivat in children ages 1–17 with thalassemia who don't need frequent blood transfusions. The medicine may help their bodies make more healthy red blood cells and reduce anemia symptoms.
Philadelphia, PennsylvaniaAges 1–17 - NCT06910813RecruitingPhase 1/Phase 2
Gene therapy trial for children with cystinosis
This trial tests a new gene therapy called DFT383 for children aged 2 to 5 with nephropathic cystinosis. It aims to see if the treatment is safe and can help improve kidney function.
Philadelphia, PennsylvaniaAges 2–5 - NCT06173518RecruitingPhase 1
CAR T-cell therapy for children with B-cell leukemia or lymphoma
This trial tests a CAR T-cell therapy that targets CD19 on cancer cells. It is for children whose B-cell acute lymphoblastic leukemia or aggressive B-cell non-Hodgkin lymphoma has come back or not responded to other treatments.
Philadelphia, PennsylvaniaAges birth–18 years - NCT05642455RecruitingPhase 1/Phase 2
Study of a new treatment for certain childhood cancers
This Phase 1/2 study tests a new therapy for children and young adults with specific types of cancer that have been treated with chemotherapy before. It may help by targeting cancer features in the tumor and using your immune system in a controlled way.
Philadelphia, PennsylvaniaAges 2–21 - NCT04457154Recruiting
Registry for teens and young adults with OSA who can’t use CPAP
This study collects information in a registry to help doctors understand outcomes for young people with moderate-to-severe obstructive sleep apnea who cannot use CPAP and may use an implantable breathing stimulation device. You might qualify if you’ve tried and couldn’t tolerate CPAP and you’re able/willing to get and use the device and return for follow-ups and sleep tests.
Philadelphia, PennsylvaniaAges 18–21 - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
Philadelphia, PennsylvaniaAges Up to 24 years - NCT06994845RecruitingPhase 3
Testing iptacopan for children with IgA nephropathy
This study tests a new medicine called iptacopan to see if it helps children with IgA nephropathy (a kidney disease). Kids who join will receive the study treatment and be monitored for safety and effectiveness.
Philadelphia, PennsylvaniaAges 2–18 - NCT04276870RecruitingPhase 2
CD19 gene-modified cells for high-risk B-cell leukemia
This Phase 2 trial studies CD19 “redirected” cells made from your own blood to treat certain high-risk or relapsed B-cell acute lymphoblastic leukemia (B-ALL). It may help by targeting cancer cells that carry a protein called CD19.
Philadelphia, PennsylvaniaAges birth–29 years
Hear when a new Pediatrics trial opens near Philadelphia, PA
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Pediatrics trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting pediatrics studies listed above.
- Children's Hospital of Philadelphia · 19 studies
- Alfred I duPont Hospital for Children · 2 studies
- Saint Christopher's Hospital for Children · 2 studies
- Abramson Cancer Center at the University of Pennsylvania
- Asplundh Cancer Pavilion
- Children's Hospital of Philadelphia (Recruiting Cohort 0 and 1)
- Children's Hospital of Philedephia
- Hospital of the University of Pennsylvania
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pediatrics studies in Pennsylvania.
Common questions
- Are there pediatrics clinical trials near Philadelphia?
- Yes. We're currently tracking 112 recruiting pediatrics studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.