Clinical trials · Philadelphia, PA
Pediatrics clinical trials in Philadelphia
We’re tracking 110 recruiting pediatrics studies with a site in or near Philadelphia — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT06994845RecruitingPhase 3
Testing iptacopan for children with IgA nephropathy
This study tests a new medicine called iptacopan to see if it helps children with IgA nephropathy (a kidney disease). Kids who join will receive the study treatment and be monitored for safety and effectiveness.
Philadelphia, PennsylvaniaAges 2–18 - NCT07159841RecruitingPhase 2/Phase 3
Study of a new drug for children with classic CAH
This study tests a new medication for children with classic congenital adrenal hyperplasia (CAH). It aims to see if the drug helps better control hormone levels and reduce the need for high doses of current steroid medicines.
Philadelphia, PennsylvaniaAges 1–17 - NCT07019922RecruitingPhase 3
A study of elsunersen for children with SCN2A-related epilepsy
This trial tests an experimental drug called elsunersen in children with a specific type of epilepsy caused by changes in the SCN2A gene. It aims to see if the drug can reduce seizures and be safe for children.
Philadelphia, PennsylvaniaAges 1 day–18 years - NCT07108374Enrolling by invitation
Improving blood transfusion practices in children's ICUs
This study tests whether a new set of guidelines can help doctors and nurses give red blood cell transfusions more consistently in pediatric intensive care. It aims to make transfusion decisions safer and more uniform for children in the ICU.
Philadelphia, PennsylvaniaAges Any age - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT06934967RecruitingPhase 3
Iptacopan study for children with PNH
This trial tests an oral medication, iptacopan, for children with paroxysmal nocturnal hemoglobinuria (PNH), a rare blood condition. It aims to see how well the drug works in kids who have not tried anti-C5 therapy or who are switching from it.
Philadelphia, PennsylvaniaAges 2–18 - NCT03827694Recruiting
Testing a noninvasive scan for serious lung mold infections in kids
This study uses noninvasive breathing/relates imaging (MRI or CT) to help diagnose mold infections in the lungs in children and young adults. It may help doctors find these infections sooner, especially in people with weakened immune systems.
Philadelphia, PennsylvaniaAges 4 months–21 years - NCT06276621Enrolling by invitation
Family Bridge Program for pediatric hospital support
This study offers a program to help families of children admitted to the hospital connect with support services. It focuses on families who may face extra challenges, such as those with public or no insurance.
Philadelphia, PennsylvaniaAges Any age - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Philadelphia, PennsylvaniaAges 6–17 - NCT05966311Recruiting
Ultrasound-guided feeding tube placement for children
This study tests a new way to place a feeding tube directly into the stomach using ultrasound instead of an endoscope. It may be a safer and less invasive option for children who need help getting nutrition.
Philadelphia, PennsylvaniaAges birth–21 years - NCT06458036RecruitingPhase 2
Selpercatinib before radioactive iodine for RET-positive thyroid cancer
This study tests whether a targeted drug called selpercatinib, taken before radioactive iodine therapy, can help treat thyroid cancer in children and young adults who have a specific genetic change (RET fusion or mutation). The drug may make the cancer more sensitive to the radioactive iodine treatment that follows.
Philadelphia, PennsylvaniaAges 2–25 - NCT07582211Recruiting
BPAP breathing support for severe asthma attacks in children
This study tests whether a special breathing mask (BPAP) can help children ages 5–17 who come to the emergency room with severe asthma attacks. The mask gently pushes air into the lungs to help them breathe more easily.
Philadelphia, PennsylvaniaAges 5–17 - NCT06173518RecruitingPhase 1
CAR T-cell therapy for children with B-cell leukemia or lymphoma
This trial tests a CAR T-cell therapy that targets CD19 on cancer cells. It is for children whose B-cell acute lymphoblastic leukemia or aggressive B-cell non-Hodgkin lymphoma has come back or not responded to other treatments.
Philadelphia, PennsylvaniaAges birth–18 years - NCT05861999RecruitingPhase 4
Risdiplam for young children with SMA after gene therapy plateau
This trial studies whether risdiplam is safe and helpful for children under 2 with spinal muscular atrophy (SMA) whose function has leveled off or declined after gene therapy. It may be an option if you saw benefits from gene therapy but then noticed a stop or setback in key abilities.
Philadelphia, PennsylvaniaAges 3 months–2 years - NCT06412666RecruitingPhase 2/Phase 3
Aficamten for teens with obstructive hypertrophic cardiomyopathy
This trial tests a new medicine called aficamten for teenagers with a heart condition that makes the heart muscle too thick and blocks blood flow. The medicine may help make the heart pump more easily and improve symptoms like shortness of breath or chest pain.
Philadelphia, PennsylvaniaAges 12–17 - NCT06582693Recruiting
Tobacco treatment for families through children's hospital
This study offers proactive, personalized help to stop smoking for adults who smoke and have a child who is a patient at Children's Hospital of Philadelphia. It aims to see if this approach works better than usual care.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04796012RecruitingPhase 1/Phase 2
Atezolizumab plus chemo for children with recurrent solid tumors
This trial tests whether a cancer immunotherapy medicine (atezolizumab) given together with chemotherapy can shrink or control solid tumors that have come back or did not respond to prior treatment. It focuses on children and young adults, including a special subgroup for rhabdomyosarcoma.
Philadelphia, PennsylvaniaAges 6 months–30 years - NCT05975671Recruiting
Survey in pediatric ICU to reduce upfront vancomycin use
This study is a survey and quality-improvement effort in participating children’s intensive care units. It aims to understand and change how doctors decide to start vancomycin (an antibiotic) when sepsis is suspected, to improve care and avoid unnecessary use.
Philadelphia, PennsylvaniaAges Any age - NCT05432648Recruiting
Fiber food introduction for children with short bowel syndrome
This trial tests if slowly adding fiber to the diet helps children with short bowel syndrome. It looks at how fiber affects digestion and overall health.
Philadelphia, PennsylvaniaAges 4 months–18 years - NCT07071298Recruiting
AERA pediatrics registry study
This registry tracks children who have a procedure called endoscopic transforaminal balloon dilation (ETBD) using the AERA device. The goal is to learn more about how this treatment works for young patients.
Philadelphia, PennsylvaniaAges Up to 18 years - NCT07080385RecruitingPhase 2/Phase 3
Study of encaleret in children with a rare calcium disorder
This trial tests a medicine called encaleret in children with a rare genetic condition that causes low calcium levels. The goal is to see if it safely helps control calcium and reduce symptoms.
Philadelphia, PennsylvaniaAges birth–17 years - NCT06739122RecruitingPhase 3
A study of dulaglutide for children with type 2 diabetes
This trial tests if a weekly injection of dulaglutide (Trulicity) can help children with type 2 diabetes control their blood sugar when used together with metformin and/or insulin. It may be an option for kids who are overweight.
Philadelphia, PennsylvaniaAges 10–17 - NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Philadelphia, PennsylvaniaAges 3–18 - NCT05024929Recruiting
Test targeted drugs to help radioactive iodine reach thyroid cancer
This study looks at whether certain cancer “targeted therapy” medicines can make radioactive iodine (RAI) therapy work better for thyroid cancer that has spread to the lungs. It also involves taking special whole-body scans to measure how much radioactive iodine gets taken up by the cancer.
Philadelphia, PennsylvaniaAges birth+
Hear when a new Pediatrics trial opens near Philadelphia, PA
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Pediatrics trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting pediatrics studies listed above.
- Children's Hospital of Philadelphia · 22 studies
- Alfred I. duPont Hospital for Children
- Children's Hospital Of Phildelphia
- Clario
- Praxis Research Site
- St. Christopher's Hospital for Children
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pediatrics studies in Pennsylvania.
Common questions
- Are there pediatrics clinical trials near Philadelphia?
- Yes. We're currently tracking 110 recruiting pediatrics studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.