Clinical trials · Philadelphia, PA
Pediatrics clinical trials in Philadelphia
We’re tracking 111 recruiting pediatrics studies with a site in or near Philadelphia — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT05127954Enrolling by invitationPhase 3
Long-term migraine tablet study for kids and teens ages 6–17
This study follows kids and teens who already took part in an earlier migraine medication study to check long-term safety and comfort with oral ubrogepant tablets. It may help families understand whether this migraine tablet is safe to keep using over time.
Philadelphia, PennsylvaniaAges 6–17 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Philadelphia, PennsylvaniaAges 2 days–17 years - NCT05509777RecruitingPhase 3
Mirikizumab for children with active Crohn’s disease
This study tests mirikizumab to reduce inflammation and symptoms in children with Crohn’s disease that is currently active. It may help if your Crohn’s has not improved enough (or stopped working) with at least one other Crohn’s medicine.
Philadelphia, PennsylvaniaAges 2–17 - NCT05371613RecruitingPhase 2/Phase 3
Testing tividenofusp alfa vs idursulfase for MPS II
This trial compares a new treatment (tividenofusp alfa) to the current standard treatment (idursulfase) in children and young adults with MPS II. It’s looking to see which option works better and is safe, especially based on age and whether the disease affects the brain.
Philadelphia, PennsylvaniaAges 2–25 - NCT05634369RecruitingPhase 1/Phase 2
NK cell and chemotherapy trial for relapsed soft tissue sarcoma
This early-phase trial studies a type of immune cell treatment (NK cells) made from donor cells, given with chemotherapy drugs gemcitabine and docetaxel. It’s for children and young adults whose bone or soft tissue sarcoma has come back or hasn’t responded to prior treatment.
Philadelphia, PennsylvaniaAges 2–40 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Philadelphia, PennsylvaniaAges Up to 21 years - NCT01893710Recruiting
Collecting children and adult belly fluid and tissue for kidney care research
This study collects samples from the belly (related to the peritoneal lining) to build a “biobank” for future research. It may help patients and families by improving understanding of kidney disease and kidney dialysis-related health issues.
Narberth, PennsylvaniaAges 1 day–90 years - NCT05294302Recruiting
Online support program for cancer parents in English or Spanish
This trial tests an online (e-health) counseling and support program for parents of children with cancer. It may help you feel better supported and more informed while caring for your child.
Wilmington, DelawareAges Any age - NCT03509961RecruitingPhase 2
Reducing total body radiation for children with leukemia transplants
This study looks at whether some children and young adults with B-ALL can safely get a transplant without total body irradiation (TBI), based on special leukemia test results. It’s meant to help lower radiation-related risks while keeping leukemia control strong.
Wilmington, DelawareAges 1–25 - NCT03401398RecruitingPhase 3
Hydrocortisone for children with septic shock in the ICU
This Phase 3 trial tests whether giving stress-dose hydrocortisone can improve outcomes for children with septic shock in the pediatric intensive care unit (PICU). It is designed for children who are already receiving strong medicines to support blood pressure because of a serious infection.
Wilmington, DelawareAges 1 month–17 years - NCT07552766RecruitingPhase 4
Lidocaine infusion to reduce opioid use in arm fracture surgery
This study tests whether giving a pain-relieving medication called lidocaine through an IV during arm fracture surgery can reduce how much opioid pain medication (like morphine) children need after surgery. The goal is to help manage pain better while using fewer opioids.
Wilmington, DelawareAges 3–18 - NCT04065438Recruiting
Study of a blood-filter treatment for FSGS not responding to meds
This study looks at how well a specialized blood-filter device (the LIPOSORBER® LA-15) works for people with primary FSGS—especially when standard steroid and other medicines don’t work or can’t be tolerated. It may help reduce disease activity, particularly in people with kidney function that is still moderate or in those after kidney transplant.
Wilmington, DelawareAges Up to 75 years - NCT05865301Recruiting
Outcomes after approved immunotherapy for young blood cancer patients
This study looks at the real-world results of treating certain B-cell blood cancers in children and young adults with commercially available immunotherapy. It may help doctors better understand how these treatments work for patients after relapse or when they need additional therapy.
New Castle, DelawareAges Up to 26 years - NCT05544019RecruitingPhase 1
Testing an investigational drug for mature B-cell cancers
This early (Phase 1) study tests SGR-1505, an experimental treatment, in people with certain mature B-cell cancers. It’s mainly designed to see how the drug works in the body and to check safety, and it may offer an option if standard treatments aren’t enough.
Newark, DelawareAges 18 years+ - NCT07627971RecruitingPhase 1/Phase 2
Gene therapy for GJB2-related hearing loss in young children
This study tests an experimental gene therapy (SKY-GJB2) designed to treat hearing loss caused by mutations in the GJB2 gene. The therapy is given directly to children ages 9 months to 7 years who have significant bilateral hearing loss, and researchers will monitor safety and whether hearing improves.
Allentown, PennsylvaniaAges 9 months–7 years
Hear when a new Pediatrics trial opens near Philadelphia, PA
We’ll email you when one opens near Philadelphia, PA — at most once a week, no account needed, unsubscribe anytime.
Pediatrics trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting pediatrics studies listed above.
- Children's Hospital of Philadelphia · 6 studies
- Alfred I. duPont Hospital for Children · 5 studies
- Christiana Care Health System-Christiana Hospital
- CVS HealthHUB - Runnemede
- Hunterdon Neurology
- Lehigh Valley Hospital-Cedar Crest
- Nemours Children's Hospital
- The Children's Hospital of Philadelphia
What taking part in a pediatrics study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pediatrics studies in Pennsylvania.
Common questions
- Are there pediatrics clinical trials near Philadelphia?
- Yes. We're currently tracking 111 recruiting pediatrics studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pediatrics study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pediatrics studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.