Clinical trials
Pediatrics clinical trials
Below are recruiting pediatrics clinical trials, each written for real people, not researchers. We’re tracking 1,375 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07216638Enrolling by invitation
Better mental health care for kids in primary care
This trial studies how to better integrate mental health care into pediatric primary care clinics across Indiana. It involves surveys, interviews, and looking at patient records to understand and improve care for children.
Indianapolis, IndianaAges 5 years+ - NCT07172100Enrolling by invitationPhase 2
Papaya Leaf Extract for Kids with Dengue and Low Platelets
This trial tests if papaya leaf extract can help raise low platelet counts in young children with dengue fever. It may offer a natural way to reduce the risk of bleeding.
KarachiAges 2–12 - NCT05610787Enrolling by invitation
Testing a device that helps move an EXCOR pediatric heart pump
This trial studies an “active driving” system that controls the EXCOR pediatric heart pump. It’s meant for children who need a heart pump as a bridge to heart transplantation, to help the pump work more safely and effectively.
Los Angeles, CaliforniaAges Up to 21 years - NCT03541785Enrolling by invitation
Using NGAL to guide fluids and start kidney-filtering in children
This study tests whether measuring a urine protein called NGAL can help doctors choose the right fluid amount and decide when to start a kidney-filtering treatment called CRRT in critically ill children with kidney injury. If it works, it may help treat kidney problems sooner and more safely.
Cincinnati, OhioAges 3 months–25 years - NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT07203001RecruitingPhase 2
MAS825 for Still's disease in children and adults
This trial tests a new drug called MAS825 for people with Still's disease that is still active despite other treatments. It aims to see if the drug can reduce symptoms like fever, rash, joint pain, or a serious complication called macrophage activation syndrome.
Cincinnati, OhioAges 1 year+ - NCT06303193RecruitingPhase 1/Phase 2
Testing a kinase inhibitor drug for MDS and MDS/MPN in adults and teens
This trial tests a drug called pacritinib in people with myelodysplastic syndromes (MDS) or MDS/myeloproliferative neoplasms (MDS/MPN). The drug targets several proteins that may help control the disease, especially for those who have not responded to other treatments.
Bethesda, MarylandAges 12–120 - NCT07482345Recruiting
Fasting strategies and anxiety in children having surgery
This study looks at whether different fasting instructions before surgery can help children be more comfortable and less anxious. It involves children having groin or penis surgery and will check their stomach with ultrasound to see how fasting affects them.
Bursa, BursaAges 2–12 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT07770490Recruiting
Food support for families with young children
This study provides free healthy food and nutrition help to families with children aged 2-6 who receive Medicaid and sometimes worry about having enough food. It aims to see if this support improves children's health and well-being.
Buffalo, New YorkAges 18 years+ - NCT07770659Recruiting
Using MRI to detect early heart transplant rejection
This study tests whether a heart MRI can detect early signs of organ rejection after a heart transplant. If successful, it could reduce the need for frequent biopsies.
Little Rock, ArkansasAges 6–25 - NCT04485559RecruitingPhase 1
Trametinib and everolimus for recurrent gliomas
This trial tests two drugs, trametinib and everolimus, for children and young adults with recurrent or progressive gliomas (a type of brain tumor). The goal is to see if this drug combination is safe and effective in treating these tumors.
Birmingham, AlabamaAges 1–25 - NCT07727538RecruitingPhase 3
Olezarsen for children with familial chylomicronemia syndrome
This trial tests a drug called olezarsen in children with a genetic condition that causes extremely high triglycerides. It aims to lower triglyceride levels and prevent pancreatitis.
Birmingham, AlabamaAges 2–17 - NCT05948943RecruitingPhase 2/Phase 3
Alpelisib for lymphatic malformations with a PIK3CA change
This trial tests alpelisib (a targeted medicine) for people who have lymphatic malformations (LyM) that cause symptoms and have a PIK3CA mutation. It may help shrink or control these lesions when other procedures are delayed until after the first 24 weeks.
Oakland, CaliforniaAges birth–100 years - NCT07582211Recruiting
BPAP breathing support for severe asthma attacks in children
This study tests whether a special breathing mask (BPAP) can help children ages 5–17 who come to the emergency room with severe asthma attacks. The mask gently pushes air into the lungs to help them breathe more easily.
New York, New YorkAges 5–17 - NCT07220785RecruitingPhase 3
Testing mibavademab for generalized lipodystrophy in adults and children
This trial tests a new drug called mibavademab for people with generalized lipodystrophy, a condition where the body can't store fat properly, leading to problems like diabetes and high triglycerides. It aims to see if the drug safely improves these metabolic issues.
Ann Arbor, MichiganAges 2 years+ - NCT06997588RecruitingPhase 2
Alpelisib for pediatric and adult PROS
This trial tests a drug called alpelisib for children and adults with a rare overgrowth condition called PROS that is caused by a PIK3CA gene change. It aims to see if the drug can safely shrink overgrowth and improve symptoms.
St Louis, MissouriAges 2–100 - NCT07766941Recruiting
Disaster protection at children's hospitals in Germany
This study looks at how well children's hospitals in Germany are prepared for emergencies or disasters. Your participation would help the researchers understand current practices and improve safety for children.
HeidelbergAges Any age - NCT07432880Recruiting
Study of children with severe MMA linked to the MMUT gene
This study is for children up to 16 years old with a severe form of methylmalonic acidemia (MMA) caused by a specific gene change (MMUT). It aims to better understand the disease and may lead to future treatments. Both children who have had a liver transplant and those who have not can join, as long as certain criteria are met.
Philadelphia, PennsylvaniaAges Up to 16 years - NCT06812130Recruiting
Surviving the pediatric intensive care unit
This study looks at how children and their healthy siblings cope after a stay in the pediatric intensive care unit (PICU). It may help doctors and families better understand what support is needed during recovery.
Singapore, SingaporeAges 4 weeks–16 years - NCT07765979Recruiting
Diet plans for teenage hives
This study tests two diets — a Mediterranean diet and a low-histamine diet — to see if they help reduce hives in teenagers with chronic spontaneous urticaria. If your child qualifies, they will follow one of these diets for a period and we will monitor their symptoms.
IstanbulAges 12–18 - NCT06458959Enrolling by invitation
Web-based care planning guide for parents in early intervention
This study is testing a new web-based guide to help parents and caregivers make care plans for their child in early intervention. If you join, you'll use the guide and share your feedback to see if it's useful.
Chicago, IllinoisAges 18 years+ - NCT07306832RecruitingPhase 1
Study of IV Pivekimab Sunirine for Children with Relapsed AML
This study tests an experimental IV drug called pivekimab sunirine for children whose acute myeloid leukemia (AML) has returned or not responded to previous treatments. The drug targets a specific marker on leukemia cells (CD123) to try to kill them.
Palo Alto, CaliforniaAges 6 months–17 years - NCT07187245Recruiting
Reality PAWS Program for Kids in Hospital Isolation
This study tests a virtual reality program called Reality PAWS to help children in isolation feel more connected and less bored. If your child is between 8 and 21, speaks English, and has typical development, they may be able to join.
Los Angeles, CaliforniaAges 8–21
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Common questions
- Are there clinical trials for pediatrics?
- Yes. Clin2 currently lists 1,375 recruiting pediatrics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatrics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatrics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.